Scribd Upload a Document

Basic design is fermentor

Search Documents

Explore

Documents

Books - Fiction Books - Non-fiction Health & Medicine Brochures/Catalogs Government Docs How-To Guides/Manuals Magazines/Newspapers Recipes/Menus School Work + all categories Featured Recent

People

26

Authors Students Researchers Publishers Government & Nonprofits Businesses Musicians Artists & Designers Teachers + all categories Most Followed Popular Sign Up | Log In / 42

Search w ithin document...

Download this Document for Free

Dynamic oxygen balance

his method contains three versions:

y

Addition of lethal agent

y

The gassing out method

y

T
y

Frequency response technique Therefore,

KL

a can be calculated as: K

L

a = Qo
2

X/C* CL
2

This method based upon oxygen balance in inlet & outlet gas streams around a fermenter. oxygen balance for the sparged air yields
y

no
2.T =1

/VL

(n o
2.i

no

2.o

)
Where

no DIRECT METHOD DIRECT METHOD

.
T = rate of oxygen transfer
VL=volume of fermentation broth

The dissolved & saturated oxygen conc.

,
CL & C*, need to be

measured experimentally in order to determine

K
L

a
C*

can be calculated from the partial pressure of oxygen in the exit gas stream in small scale fermenter
.

,(C* CL)log.mean, between the inlet & outlet of the fermenter should be used in the following equation determining ont
.
y

ut in large scale fermenter, the assumption of a perfectly mixed gas stream may not be valid
. S

o, the log
.

mean of the driving force i

.

e
. C
KL

a,
KL

a =
2

no

.
T

/ (C* C
L

)
log.mean

Yo
y

The rate of oxygen transfer can be related to the growth rate of microorganism using the Oxygen yield coefficient according to the following eq
.

no
2.T

= uX/Yo
2
y

Where
U

= specific growth rate of microorganism

X=

cell conc
.

OXYGEN YIELD COEFFICIENT OXYGEN YIELD COEFFICIENT METHOD METHOD

2=

yield coefficient of oxygen

no
2

.T= oxygen transfer rate

Onceno
2

.T

is determined by this equation then equation

1.

) can be used to calculate the

KL

a provided that the dissolved ox

yg

en conc
.

is measured
.

y y

Efficient heat transfer is important in controlling

the temperature during sterilization operations

y

Heat generated in the fermentor needs to be dissipated by cooling

y

Optimum temp. should be maintain in the fermentor

HEAT TRANSFER HEAT TRANSFER

This can be achieved by:
E

xternal jackets
I

nternal coils
E

xternal surface heat exchanger

Transport of reactants to & from phase to the biological component has a significant impact on the performance of the reactor.
y

TRANSPORT OF NUTRIENT TRANSPORT OF NUTRIENT

y

It is affected if the rate of the transport of

the limiting nutrients is slower than the rate of utilization by the cells.
Fermenter Design
Download this Document for FreePrintMobileCollectionsReport Document This is a private document.

Info and Rating

Follow PHR NIKHIL

Share & Embed Related Documents

PreviousNext

1.

p.

p.

p.

2.

p.

p.

p.

3.

p.

p.

p.

4.

p.

p.

p.

5.

p.

p.

p.

6.

p.

p.

p.

7.

p.

p.

p.

8.

p.

p.

p.

9.

p.

p.

p.

10.

p.

p.

p.

11.

p.

p.

p.

12.

p.

p.

p.

13.

p.

p.

p.

14.

p.

p.

p.

15.

p.

p.

p.

More from this user

PreviousNext 1.

42 p.

38 p.

Recent Readcasters

Add a Comment
9064a65b0df56cbb87d81021993c802b1c25e6c9

Submit Characters: 400

document_comment_errors 4gen

You Must be Logged in to Download a Document

Use your Facebook login and see what your friends are reading and sharing. Other login options Login with Facebook

I don't have a Facebook account Send me the Scribd Newsletter, and occasional account related communications. Discover and connect with people of similar interests. Publish your documents quickly and easily. Share your reading interests on Scribd and social sites.

Already have a Scribd account? Email address:

Submit Upload a Document

Basic design is fermentor

Search Documents

Follow Us! scribd.com/scribd twitter.com/scribd facebook.com/scribd About Press Blog Partners Scribd 101 Web Stuff Support FAQ Developers / API Jobs Terms Copyright Privacy

Copyright 2011 Scribd Inc. Language: English