CONTENTS

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T
T
MHC
T

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44 93-97
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32
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Rapid Review
Dental
Microbiology and
Immunology

Owner

34 93-97

14
15
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17 93-97

U l`WWLL ver09.0320

2
Type of Defense Mechanisms
A. ()
1.

2.


3.

IgM IgG -

4.
1st 2nd
B. ()

1.
2.
3.

4./(
tolerance)

A.
1.
a. C3a C5a



b. bradykinin

c.1st 2nd

2.
a. IL-1TNF-
IL-6
(pyrogens)
b. IL-12 TH (
)

B.

c. C9 MACC5b6789n

* C9 Tc
2.

C3bC4b

C3aC5a

C3aC5a

C3 C5 C3b
(membrane-attack complex; MAC)

A.
B
C3d

1.IgM IgG - B.

1.C1
2.(
)
B.
1.MAC
C.
a.MAC C5 C5
b. C6C7C8 C5b C5b678

2.C3 C5 DAFH I
* decay accelerating factor
3. C3a C5a

1. C1 C4
2. C5 C9

A.
1.(opsonins)

a.C3b C4b CR1

b.IgM IgG Fc

2.
3.

a.

b.

B.

C.

2.eosinophils
a.
b.
3.basophils mast cells
a.
b. IgE
c.

B.

1.
a.()
b. MHC CD4TH
c.(P.02)
d
e.
2.()

A.
1.neutrophils;PMNs (*polymorphonuclear)
a.
b.

T NK

C. dendritic cells
1. ex:IL-12
2. Langerhans
3. CD4TH CD8TC

6
D. (nature killer cellNK cell)

* MHC
(large granular lymphocytes;
* MHC
LGLs) B T
antigen-presenting cellsAPCs
1.NK
T
MHC T

A.
2.NK
MHC nave T
a.
1.TCR VDJ
* Tc perforin
* NK
TCR
MHC Tc MHC
b. antibody-dependent cellular cytotoxicity
* ADCC
NK Fc
E.
1.B
2.T T (TCR)
MHC
a.helper T cells; THCD4 MHC
b.cytolytic T cells; TcCD8 MHC
* major histocompatibility complex; MHC
MHC MHC
T

T TCR

2.

B. - nave T cell T

A. T cell receptor; TCR

1.Major MHC

a.TCR APCs -MHC

1. T cell TCR
b.CD4 CD8 APCs MHC
2.TCR MHC
2. MHC
3. TCR CD3 T

cell
a. T
B. T T
b.T APCs
1.CD4 CD8 T
(exCD28:B7 )
a.CD4 TH APCs MHC
b.CD8 Tc MHC
2. exCD2
T APCs T
3. exCD28CTLA-4
T
MHC
A. ( MHC)
1.
2.CD8 T
B. ( MHC)
1.
2.CD4 T

8
T

A. CD4 T
1.TH0

3.TH2 IL-4IL-5IL-6IL-10
a.()
b.
c.(IgE)
B. CTL
CD8 Tc cytotoxic T lymphocytes

1. CTL
a. perforin ( C9)
b.
apoptosis
2.CTL Fas Fas

MHC
A.
1.

a.IL-12 TH1
b.IL-4 TH2
2.TH1 IL-2
a. B.

b.
C.
c.()

2.10 T
CTL
3.
Graft-versus-host disease; GVHD

HLA mixed lymphocyte reaction; MLR


A.
B (antigen)

1. VL CL
2. VH CH1CH2
3.()
B. Fab Fc
1.Fab VLVH
2.Fc Fc

3. B

Fc

PMNs Fc

PMNsNK
Fc

IgE Fc

Fc

IgA Fc

(C1)

10
IgM
a. IgM()
1.
2. J
3.
4.(rheumatoid factor)()
b. IgM
B
IgA
(ex)
1. J
2.
3.

IgG
()
1.
2.
3.
4.IgG1

IgD
1. B
2. B
B

IgE
1.()
2.
3. Fc

A. B
A.
nave B (P.05)
B. -
1.naveB B.
CD4 TH

(IgM )
2.B B
C. -
1. TH B
C.

1.
2.
IgM
1.
2.
3.ABO
4.

2.

A.
B. (IgG)(P.04)

1. ELISA
* enzyme-linked immunosorbent assay
RIA
2. EIA

C.
D.
E.
F.

(IgG IgM)
(IgM)
IgGE A
IgA

* enzyme immunoassay

G. -

11

12

A.
1.
2.NK
3.
4. IL-1IL-6TNF
5.APCs
B.
1.nave CD4 TH APCs MHC
2.nave B ++TH
IgM

A. (immediate)
IgE

3. CD4 TH TH1TH2
4.CD8 Tc (
MHC )
5.B
()()
a.TH1 IgG1
b.TH2 IgG IgE IgA
6.
7.
8.(TH1)
C.
B

1. Fc
IgE(*slow-reacting substance of anaphylaxis)
2. SRS-A
3. -
()
4. IgG IgE

B.
C.
1.
1.-
2.
2.
a.-
MAC
3.
a. or
b. NK Fc

3.
b. 1-2
a.
c.
b.

D. (delayed-type)
c. RBC (Rh )
1. CD4TH1 IL-2 TNF
d.
2.
a.

b.CD8 Tc MHC

3.

13

14


A.
1.
2.AB

c.TH Tc
(extype I DM; insulin-dependent)
C. HLA
* human leukocyte antigens

B.
a.
b.

c.DNA

A.
1.
2.
3.
B.

MHC

1.
(exGraves disease; myasthenia gravis)
2.
a.
ADCC (P.06)
b.
(exsystemic lupus erythmatous ;SLE)

IL-1

IL-2

TH1

IL-3

TH

IL-4

TH2

IL-5

TH2

IL-6

TH2 endothelial cell

IL-10

TH2

IL-12

IFN-

TH1 NK

TNF-

TNF-

TH1 Tc

TGF-

T B

15

16

59. secretory IgA

(A)C-chain (B)light chain (C)secretory component (D)J-chain
60. classical pathway
(1)IgG (2)IgM (3)IgA (4)IgD (5)IgE

(A)
(C)

(A)(2)(4)(B)(3)(5)(C)(1)(2)(D)(1)(4)
61.Atopic dermatitisallergic eczema
(C)
(A)IgG (B)IgM (C)IgE (D)IgA
63. B B B hepatitis B (D)

(A) (B) HBIGhepatitis B immunoglobulin

(C) HBIGhepatitis B immunoglobulin
(D) HBIGhepatitis B immunoglobulin B
54.immunoglobulinplacenta
(C)
(A)IgA (B)IgE (C)IgG (D)IgM
55. AIDS
(A)
(A)CD4 (B)CD8 (C)CD12 (D)CD16
60.salivagingival crevicular fluid
(A) IgAsecretory IgA IgG
(B) lactoferrin
(C)
(D) pH6.757.25 pH7.27.4
61. T
(A) (B) (C) (D)

(B)

(D)

17

18
62.dental pulp periapical granuloma

(B)

(A) bone resorption IL-5 (B) prostaglandin

(C) transferrin
(D) lysozyme
55. B development
(A) (B)

(C)

(C) (D) B
56. J J chainimmunoglobulin (A)

(A)IgA (B)IgD (C)IgE (D)IgG

57.natural killer cell
(A)
(A) (B)
(C)
(D)adaptive immune response
55.
(D)
(A) T-helper osteoclast activating factorbone resorption
(B) T lymphokines B (C) T-suppressor
(D) Th2
56.
(A)Ouchterlonys test (B)immunoelectrophoresis
(C)immunoprecipitation
(D)cytotoxicity

(D)

63. lactoferrin
(A) (B) (C) (D)
64.neutrophil
(A) myeloperoxidase (B) lysozyme (C) defensins (D) IFN-

(A)
(D)

54. 7075%
(A) IgM (B) IgG (C) IgA (D) IgE
55.cytokine T
(A) IL-1 (B) IL-3 (C) IL-6 (D) IL-9

(B)
(A)

60.PCR (C)
(A)
(B)
(C) (D)
62.delayed type
(D)
(A) IL-1 (B) IL-2 (C) IL-6 (D) IL-10
63. IL-1interleukin-1
(D)
(A)macrophage
(B)osteoclast
(C)receptor (D)osteoblast
57.antigen presenting cell T T (B)
T-cell receptor T
(A) ClassMHC antigen (B) ClassMHC antigen (C) IgE (D) LFA-1
60. natural killerNK
(A) B lymphocyte (B) cytotoxic T lymphocyte
(C)
(D)
61.saliva

(D)

(B)

(A)salivary glandplasma cells AIgA

(B)lactoferrin
(C)polymorphonuclear leukocytes
(D)complement

19

20
54. IL-2 T lymphokines

(D)

(A)tumor necrosis factor-TNF-

(B)B-cell growth factorBCGF
(C)B-cell differentiation factorBCDF (D)macrophage activation factorMAF
56.professional antigen-presenting cells (A)
MHC class II major histocompatibility complex antigen
(A)B B cells (B)T T cells(C)natural killer cells (D)mast cells
61.immune responseinteraction T cell-macrophage (A)

(A)T cell macrophage class I MHC (B)macrophage partial degradation

(C) MHC
(D)macrophage costimulatory signal T-cell
62. GIgG 4 subclassIgG1IgG2IgG3 IgG4
(A)
(A)IgG1 (B)IgG2 (C)IgG3 (D)IgG4
54.Hapten-proteincarrierconjugate anti-hapten
(B)
(A)helper T hapten
(B)helper T proteincarrier
(C)B suppressor T (D)B proteincarrier
46.
(A)
(A)salivary pellicle (B)lactoferrin (C)sIgA (D)peroxidase
58.Chronic granulomatous disease
(A)phagocytosis (B)B cell deficiency (C)T cell deficiency (D)defects in complement system

(A)

45.Natural killer cell

(1) lymphocyte CD3
(2) granule
(3) MHC-I

(B)

(4)(opsoinized)
(A)(1)(2)
(B)(2)(4)
(C)(2)(3)
(D)(2)(3)(4)
54.Dendritic cell
(A) (B) B (C) T (D)
55. immunoglobulin
(A)IgM (B)IgD (C)IgE (D)IgG
57. chemokine
(A)
(B)
(C) cellular matrix
(D) chemokine
63.periapical bone
lymphotoxin (B)TNF- (C)osteoclasts (D)IL-10
59. (immunodeficient)
(A) (killed bacteria)
(B) (attenuated live vaccine)
(C) (subunit vaccine) (D) (inactivated virus)

(A)
(A)
(A)

(D)
(B)

21

22
A.
1.nucleoid
a. DNA
(histone)

b.
2.

3.PLASMIDS
DNA
B.

G(+)

G(-)

G(+)cell wall

G(-)cell wall

G(+) cell wall

G(+)
A.
1.
2.
B.
1.
2.
G(-)
C.

D.
1.
2.
3. EDTA

G(-) cell wall

E.
(ex:
-lactamase)
Gram stain(+)=
Gram stain(-)=
ex:

A. mycolic acids
B.
Corynebacterium, Nocardia mycolic acid
C. mycolic acid acid-fast
stains

23


A.

B.
1.
a. obligate aerobes
b. anaerobes
c. facultative anaerobes
2.
a.
b.
A.
C.
1. DNA
1.DNA (replication origin)
2.operon
2. septum
a.

polycistron operons
D.
b. RNA
G(+)
c.lac

24

B.
F. exotoxin G(+) G(-)
1. plasmids DNA

G(-)
G(+)G(-)

2. bacteriophages

a. lytic phages

b. lysogenic phages

TNFIL-1IL-6

cAMP
()

3. transposons

DNA DNA

()

G. evasion
A.
1. encapsulation
B.
C.
D. ( bacteremia)
E. endotoxin= LPS G(-) cell wall
1.G(-)
2.
mediator

2.
3. IgA
4.IgG
5.G(-) O
6. DNA
a.
b.
c.

25

26

Gram-Positive Cocci
A. Staphylococcus

1.S. aureus
2.S. epidermidis
3.S. saprophyticus
B. Streptococcus
agar plate
1.S. pyogenes
2.S. agalactiae
3.Viridans group
4.S. penumoniae penumococcus
C. Enterococcus faecalis
Enterococcus faecium

B. Clostridium
()
1.C. perfringens
2.C. tetani
3.C. botulinum
4.C. difficile
C. Corynebacterium diphtheriae

Gram-Positive Toxigenic Rods

A. Bacillus

1.B. anthracis
2.B. cereus
3.B. subtilis
4.

27

28

Gram-negative Rods
A. Lactose-Fermenting Enterobacteriaceae

1.Escherichia coli Septicemia

2.Klebsiella pneumonia
3.Enterobacter
4.Citrobacter
5.Serratia
B. Non-Lactose-Fermenting Enterobacteriaceae

1.Salmonella
2.Shigella
3.Yersinia pestis
4.Yersinia enterocolitica
5.Proteus mirabilis

B. Bordetalla pertussis
pertussis whooping cough
C. Heamophilus

1.H. influenza
2.H. ducreyi
D. Legionella pneumoplila
Gram-Negative, Oxidase-Positive Motile Rods
A. Pseudomonas aeruginosa
1.
2.
3.PseudomonasMycobacterium Legionella

B. Vibrio

1.V. cholerae
Gram-Negative Cocci and Coccobacilli
2.V. vulnificans

A. Neisseria
C. Campylobacter and Helicobacter
N. meningitidis N.gonorrhoeae
1.C. jejuni

N.
1.N. meningitidis
2.N. gonorrhoeae

2.H. pylori

29

A. pellicle
B. proliferation and aggregation

30

A. 10hrs supragingiva plaque G(+)S. mitior

B. 3-8hrsStreptococcus S. mitior
C. supragingival plaque G(+) rods

Pellicle

1.A. viscous 2.A. naselundii 3.A. odontolyticus

A.
D. supragingival plaque 3hrs
1. splint
1.
A. israelliG(-) rod
2. bacterial colonization
2.
VillonellaG(-) rod
3. bacterial colonization pellicle
3.:
bacteria intercellular matrix
S. mutansS. SanguisLactobacillus spA. Viscosus
4.pellicle
E. supragingivalG(+) saccharolytic
B. Pellicle G(+)streptococci

electrostatic
F. subgingivalG(-) saccharolytic and proteolytic
C. main componentglycoproten
D. pellicle Ca++
G.
E. dental plaque activity and component
1.oral bacteria H.
2.
3.oral bacteria dextranase(GTF)
a. plaque
b. adherencecell-cell
F. plaque pH 5.0 aciduric
S. mutans L. casei ()

1. G(-)
2.Actinomyces
S. salivariusS. Salivarius
dentaogingival margin
1. cocci
2.
G(-) motile species

A.
1.dental plaque

Periodontitis
A. Adult periodontitis
1. P. Gingivalis Ab
2. immunological complex

3. gingival bacteria immediate hypersensitivity

2.Calculusphysical stimulation gingibal bleeding

cell-mediated immunity
3.bacterial component or products
4.gingivaalveolar bonePDL
a.spore
B. ANUG
b.endotoxin hyaluronidase

1.
c.productpolysaccharide and polypeptides

a.Bacteroides intermedius 8-15%
d.capsule
abscess formation
b.unnamed intermediate spirochetes

no abscess
2.ANUG
e.extracellular polysaccharide
a.Bacterial zone
most superficial
B.
*small intermediate size rods
1.Bacteroides intermedius
*large spirochete
2.Actinobacillus actinomycetemcomitans
5%-10%CO2
3.Porphyromonas gingivalis IL-8 PMNs
4.Fusobacterium
5.Spirochetes
6.Lactobacillus
*B. Intermedius pregnancy gingivitis
estradiol progesterone

b.Neutrophil
rich zone
*numerous spirochetes
*Rod shaped bacteria interspersed between PMNs
c.Necrotic zone
*necrotic tissue
*spirochetesrods
d.Zone of spirochetal infiltration (deepest area)
C. A. a serotype b

31

Streptococcus mitis
Streptococcus snaguis
Staphylococcus epidermidis
Rathia dentocariosa
Actinomyces viscosus
Actinomyces naeslundii
Small spirochetes
A.
B.
C.
D.

32
6.enamel cariesS. mutans(in plaque)
Lactobacilli(in saliva)
7.pulpitisperiapical periodontitisAnachoresis
8.Nocardia

A. anaerobes G(-)Bacteroides

B. endodontalis periapical infection

B. anaerobes
G(+) cocci total flora 2/3
1.
filamentous formssmall spirochetesfusiform
2.
motile rods
C. Periapical infection of endodontic origin
G(-)
1.acuteacute apical periodontitis
gingival crevice fluid
acute alveolar abscess

1.spirochetes black-pigmented bacteroides

2.IgG

A. caries : Streptococcus mutans

1.Pit and fissure cariesS. mutansLactobacillus sp.
2.smooth surfaceS. mutans
3.dental cariesLactobacillus sp.
4.root cariesActinomyces viscosusA. naeslundii
5.deep caries lesionLactobacillus acidophilus

2.chronicperiapical granuloma
periapical cyst
3. LPS endotoxinlipopolysaccharide
type II collagen

 Mycobacteria

A. Rickettsia
(acid-fast stain)
1.R. rickettsii

A. Mycobacterium Tuberculosis
Rocky mountain spotted fever
1.

2.R. typhi

endermic/murine typhus
2.
B. Brucella
3.(tubercles)
C. Francisella tularensis tularemia
4. TH1 D. Listeria monocytogenes

1.
B. Atypical Mycobacteria
a.
C. Mycobacterium leprae
b.()
1.TH1
(tuberculoid)
2.
2.TH2
(lepromatous)
Chlamydia

A. C. trachomatis
B. C. psittaci
C. C. pneumoniae

a.granulomatosis infantiseptica

b.
2-3

()

33

34
53.Streptococcus pyogenespharyngitis

(C)

TuberculosisDiphtheria(C)Scarlet fever(D)Chicken pox

54.epidemic typhus
(A)Rickettsia(B)Mycoplasma(C)Spirochetes(D)Chlamydiae

(A)

55.macrophagesmultinucleated giant cells (B)

(A)Streptococcus pneumoniae(B)Mycobacterium tuberculosis
(C)Treponema pallidum
(D)Mycoplasma pneumoniae
57.ANUG
(B)
(A)Fusobacterium nucleatum Tannerella forsythensisBacteroides forsythus
(B)Prevotella intermedia spirochetes
(C)Porphyromonas gingivalis Capnocytophaga spp.
(D)Actinobacillus actinomycetemcomitans
58. (A)
(A)Neisseria
(B)Staphylococcus aureus
(C)Propionibacterium
(D)Lactobacillus
62.
(C)
(A)20 (B)40 (C)70 (D)95
64. Legionella
(A)Streptococcus and Pseudomonas
(B)Fusobacterium and Micrococcus
(C)Micrococcus and Mycobacterium
(D)Pseudomonas and Mycobacterium

(D)

53.mutation
(A) DNA
(B) X-ray thymine dimers
(C)Ethidium bromide DNA

(B)

(D)suppression
59. progressive periodontitis
(B)
(A)Mitsuokella
(B)Tannerella forsythensisBacteroides forsythus
(C)Prevotella oralis
(D)Eikenella corrodens
64.biological indicator (A)

(A)Bacillus
(B)Staphylococcus
(C)E. coli
(D)Clostridium
53.
(B)
(A)
(B) pyrimidine dimer DNA
(C)
(D)enzyme
54.operonoperon

(A)

(A)operon
(B) lac operon lactoseoperator
(C)lac operon attenuation
(D) lac operon repressor

35

36
61.

(A)

(A) (B)T (C) (D)B

62.
(A) (B)63145.430

(B)
(C) 12120

63.autoclave
(A)121C3 (B)121C15 (C)160C3 (D)160C15
58. Streptococcus pneumoniae colonization
(A) (B) (C) (D)
60. 5% -10% CO2
(A) Actinobacillus actinomycetemcomitans
(B) Prevotella intermedia
(C) Porphyromonas gingivalis
(D) Fusobacterium nucleatum
61. pH 5.0
(A) Streptococcus salivarius
(B) Actinomyces viscosus
(C) Streptococcus mitis
(D) Lactobacillus casei
62. Porphyromonas gingivalis
(A)
(B) negative trypsin-likeBANAactivity
(C)black-pigmented Bacteroides
(D)collagen

(D)
(B)
(C)
(A)

(D)

(B)

56.
(A)Yersinia enterocolitica
(B)Campylobacter jejuni
(C)Salmonella typhi

(D)

(D)Helicobacter pylori
58.Streptococcus 19
(A) (B) (C) DNA (D)
59.Actinobacillus actinomycetemcomitans
(A) T
(B) B
(C)leukotoxin (D)cytokine
61.acute necrotizing ulcerative gingivitis
(A) P. intermedia spirochetes
(B)

(B)
(C)

(C)

(C)necrotic zonespirochetes
(D) HIV
53.
(B)
(A)capsule
(B)lipoteichoic acid
(C)lipopolysaccharide (D)
54. 25 12
(A)
(A)
(B)
(C)
(D)

Streptococcus pyogenes
Clostridium difficile
Salmonella enteriditis
Shigella dysenteriae

37

38
55.

(B)

(A)pellicle (B)dental plaque(C)calculus (D)leukoplakia

59.
(A) IgA (B) IgG (C) IgM (D) IgD

(B)

63.

(B)

(A) Staphylococcus epidermidis (B) E. coli (C) Fungi (D) Micrococcus luteus
64.
(A) (B) (C) (D)
55.replicon
(A)plasmid (B)phage(C)chromosome (D)transposon
57.exotoxin
(A) (B)
(C)
(D)high immunogenic
58.periodontopathic organisms
(A)Capnocytophaga chemotaxis of neutrophils
(B)P. gingivalis immunoglobulin and complement proteins
(C)association
(D)P. micros invasion
59.plaquepellicle
(A)gram-negative Streptococcus
(B)gram-positive Streptococcus
(C)gram-positive rods
(D)filamentous bacteria

(A)
(D)
(C)

(D)

(B)

64.rubber dam
(A)plaque bacteria (B)salivary bacteria (C)dental unit water bacteria (D)periodontal bacteria
55.exotoxin
(A)toxic shock syndrome (B)scarlet fever
(C)typhoid fever

(C)
(C)

(D)botulism

56.flagella
(B)
(A)(B)(C)(D)
57.hemin
(A)
(A)Porphyromonas gingivalis
(B)Treponema denticola
(C)Capnocytophaga
(D)Streptococcus mutans
(A)
59.maturation
(A)colonization
(B)
(C)filamentous
(D)crevicular fluidhemin
61.hippurate
(A)Fusobacterium nucleatum (B)Fusobacterium periodonticum
(C)Fusobacterium alocis
(D)Fusobacterium sulci
63.collagenasecollagen

(B)

(B)

(A)Eikenella corrodens
(B)Porphyromonas gingivalis
(C)S. sanguis
(D)Lactobacillus

39

40
64. Peptostreptococcus microsP. micros P. micros (B)

(1) blood agar hemolytic

(2)
(3)alkaline phosphatase
(4)strictly anaerobic
(A)(1)(2)(3)
(B)(2)(3)(4)
(C)(3)(4)(1)
(D)(4)(1)(2)
44. oral streptococci alpha hemolytic
(A)S. mutans (B)S. salivarius (C)S. mitis (D)S. intermedius

45. obligate anaerobe

(A)P. gingivalis (B)F. nucleatum(C)A. actinomycetemcomitans (D)Treponema denticola
47.
(A)Bacillus subtilis
(B)Mycobacterium tuberculosis
(C)Bacillus stearothermophilus (D)Enterococcus faecalis

(A)
(B)
(C)
(D)
(C)
(C)

49.
(B)
(A)Clostridium difficile (B)Helicobacter pylori(C)Salmonella typhimurium (D)Listeria monocytogenes
50.pharyngitis
(A)
(A)Streptococcus pyrogenes (B)Mycoplasma pneumoniae(C)Hemophilus influenzae (D)Legionella pneumophila

52.Septicemia
(A)Escherichia coli (B)Streptococcus oralis (C)Staphylococcus aureus (D)Bacteroides fragilis
53.dentin
(A)Lactobacillus (B)Actinomyces (C)Streptococcus (D)Veillonella

(A)

54.initiation

(A)

(A)Streptococcus mutans (B)Actinomyces naeslundii(C)Lactobacillus acidophilus (D)Veillonella

56.
(A)Anaerobic streptococci
(B)Mycobacterium smegmatis
(C)Lactobacillus acidophilus (D)Mycoplasma pneumoniae
59.Legionnaires disease
(A) (B) (C) (D)
60.
(A)Acute necrotizing ulcerative gingivitis (B)Hormone induced gingivitis
(C)Chronic marginal gingivitis
(D)Desquamative gingivitis

(A)

(B)
(C)
(A)

(A)
(A)
(B)
(C)

(D)
42. (dental plaque) (glucan) glucan (B)

(A)fructosyltransferase (B)glucosyltransferase (C)sucrase (D)dextranase

43. Streptococcus mutans
(A) DNA AT GC
(B) Mitis-salivarius
(C) (D) IgA

(C)

41

42
44. Treponema

(C)

(1)
(2) Streptococcus
(3) flagella
(4)
(A)(1)(2)(3)
(B)(2)(3)(4)
(C)(1)(3)(4)
(D)(1)(2)(4)
46.
(A) bacteria peptidoglucan
(B) bacteria chromosome (circular form)
(C)bacteria cell membrane ATP
(D)bacteria
48. mutans streptococci
(A)Streptococcus rattus
(B)Streptococcus mutans

(B)

(B)

(C)Streptococcus cricetus (D)Streptococcus downei

49.subsurface demineralization
(A)
(B)white-chalky

(D)

(C) (D)
50. Actinobacillus actinomycetemcomitans (A.a)
(A)A.a serotype a (B)A.a serotype b (C)A.a serotype c (D)A.a serotype d

(B)

51.
(B)
(A)Streptococcus mutans (B)Streptococcus salivarius (C)Streptococcus sanguis (D)Streptococcus mitis
52.
(A)
(A)Veillonella spp.(B)Eikenella corrodens(C)Campylobacter rectus(D)Actinobacillus actinomycetemcomitans
53.Porphyromonas gingivalis (host response)
(1) (capsule)
(2)(leukotoxin)
(3)catalase (protease)
(A)(1)(2)
(B)(1)(4)
(C)(2)(4)
(D)(2)(3)
56.
(A)Actinobacillus actinomycetemcomitans
(B)Prevotella intermedia

(B)

(B)

(C)Bacteroides forsythus
(D)Fusobacterium nucleatum

43

44
93-97
56.thrushdenture stomatitis
(A)Human herpesvirus 1(B)Coxsackievirus
(C)Candida albicans
(D)Treponema pallidum

(C)

4.blastomycosis

(B)

(A) (B) (C) (D)

56.German measles
(A)measles virus (B)mumps virus (C)rubella virus (D)cytomegalovirus
57.HerpanginaHand-foot-and-mouth Disesase
(A)varicella-zoster virus (B)human herpesvirus
(C)Epstein-Barr virus
(D)Coxsackievirus
59.Prion mad cow disease prion
(A) RNA RNA genome
(B)
(C) formaldehyde prion (D)spongiform encephalopathy
60.high levels ofparasitism
(A)Plasmodium malariae (B)Plasmodium vivax (C)Plasmodium falciparum (D)Plasmodium ovale

(C)
(D)

(D)

(C)

64. HIV infection

(A)CD4 T lymphocyte
(B)CD4 T lymphocyte
(C) Kaposis sarcoma
(D)phagocyte

(D)

54.sexual intercoursetransplacental
(A)cytomegalovirus
(B)rubella virus
(C) B hepatitis B virus (D)mumps virus

(D)

57.
(A) Microsporum canis
(B) Trichophyton schoenleinii
(C) Epidermophyton floccosum (D) Aspergillus flavus

(D)

59.human immunodeficiency virusvirion

(C)

(A) 2 RNA positive-strand RNA genome

(B)integrase DNA
(C)reverse-transcriptase mRNA cDNA
(D) gp120
53.
(A) glutaraldehyde 2 iodophors 2
(B) H2O2 3 iodophors 2
(C) H2O2 3 quaternary ammonium compounds 2
(D) 70 1
64.
(A)
(B)
(C)
(D)
58.Epstein-Barr virus
(A)
(B)
(C)
(D)

(B)

(B)

(D)

infectious mononucleosis
Burkitts lymphoma
oral hairy leukoplakia
Kaposis sarcoma

45

46
62. B

(C)

(A)
(B)
(C)high risk group
(D) B
60.angular cheilitis
(A)
(A)Candida albicans
(B)Capnocytophaga sputigena
(C)Actinomyces viscosus (D)Lactobacillus caseii
53. yeast
(B)
(A) chitin ergosterol (B) ascospores
(C) nuclei mitochondria
(D) endotoxin exotoxin
58. 6 X
(B)
(A)Parainfluenza virus (B)Rotavirus
(C)Adenovirus
(D)Respiratory syncytial virus
60. 20 CD4+ 120/mm3 (B)
300-1,200
(A)Influenza A virus
(B)Mycobacterium pneumonia
(C)Mycoplasma pneumonia (D)Chlamydia pneumonia
62.genomem RNA
(A)Double-stranded DNA viruses
(B)Double-stranded RNA viruses
(C)Plus-stranded RNA viruses
(D)Minus-stranded RNA viruses

(C)

41. B
(A)1-3% (B)5-10% (C)15-20% (D)30-50%
42. B
(A)C (B)D (C)E (D)G

(B)

43 .Kaposis sarcoma HIV

(C)

(A)Epstein-Barr virus
(B)Cytomegalovirus
(C)Herpesvirus 8 HHV-8(D)Candidiasis
48.
(A)Hepatitis B
(B)Mycobacterium tuberculosis
(C)Bacillus subtilis (D)Creutzfeldt-Jakob disease particle

(D)

51.AIDS fungal pneumonia

(A)Blastomycosis (B)Histoplasmosis (C)Cryptococcosis (D)Pneumocystis carinii
55.
(A)Mumps virus (B)HIV (C)Actinomyces (D)Mycobacterium tuberculosis
57. HIV HIV
(A)30% (B)10% (C)3% (D)0.3%
41. SARS
(A)double stranded DNA (B)single stranded DNA (C)single stranded RNA (D)double stranded RNA
47. (interferon)
(A)
(B)

(B)

(D)
(A)
(D)
(C)
(C)

(C)
(D)

47

48
58. (herpes virus)

(A)

(A) (cytomegalovirus)
(B) (varicella zoster virus)
(C)EB
(D)A (hepatitis A virus)
60. (common cold)
(A) (mumps)
(B) (influenza virus)
(C)EB
(D) (rhinovirus)

(D)

^^
by