IntroductiontotheCourseof Introduction to the Course of EndocrineandMetabolism

AtifHassanKhirelsied,B.Sc.,M.Sc.,Ph.D.f FacultyofMedicine y InternationalUniversityofAfrica,Khartoum,Sudan

Courseintroduction Course introduction

Theimportanceofendocrinesystem
Functionalcoordinationofbodysystems. Communication among various parts of the body Communicationamongvariouspartsofthebody. Conservationofhomeostasis. Adaptationtoenvironmentalchanges.

Courseintroduction
Number: Title: Coordinator: Duration: Credithours: Course Course committee FMHS511 EndocrinologyandMetabolism Dr.AtifH.Khirelsied(phone:0122169743) 6Weeks 6hrs Dr.AtifH.Khirelsied,Dr.Fatma Elsmani,Dr.Ibtisam Ali, NutritionalBiochemistry,Introductiontothestudyofdiseases, N tritional Biochemistr Introd ction to the st d of diseases ManandEnvironment,GrowthandDevelopment,Gastro intestinaltract. Lectureroom(150students),computerandmultimedia projectors,dissectionroom, museum,libraryandlaboratory.

Prerequisites

Facilitiesand Requirements

Introduction
Thiscourseprovidesanoverviewofthebasic This course provides an overview of the basic characteristicsoftheendocrinesystemand elaboratesonthemorphology,biochemistry, physiologyandpathologyofvariousglands associatedwiththecommonclinicaldisordersofthe associated with the common clinical disorders of the endocrinesystem.

Course

GeneralObjectives

CourseObjectives Course Objectives

Uponsuccessfulcompletionofthiscourse,the Upon successful completion of this course the studentsshouldbeableto;
1. Describetheoverallorganizationoftheendocrine systeminthehumanbody,andidentifythemajor glandsandtheirlocations.

CourseObjectives Course Objectives

Uponsuccessfulcompletionofthiscourse,the p p , studentsshouldbeableto; 2. Outlinetheroleofhormonesinthecontrolof bodyfunctioninganddescribetheimportance ofhormonesinhealthanddiseases.

CourseObjectives Course Objectives

Uponsuccessfulcompletionofthiscourse,the studentsshouldbeableto; 3. Identifydifferentclassesofhormonesand hormonereceptors,anddescribetheprinciples ofmolecularsignalingatcellularlevel. f l l i li t ll l l l

CourseObjectives Course Objectives

Uponsuccessfulcompletionofthiscourse,the studentsshouldbeableto; 4. Describethemajormetabolicpathwaysof carbohydrates,lipids,proteinsandnucleotides metabolism,andexplainhowthesepathways arecoordinatelyintegratedbytheendocrine are coordinately integrated by the endocrine system.

CourseObjectives Course Objectives

Uponsuccessfulcompletionofthiscourse,the Upon successful completion of this course the studentsshouldbeableto; 5. Identifytheimportantclinicalconditions associatedwithhormonalandmetabolic disorders,andlearnhowtoevaluateendocrine disorderscommonlyseeninprimaryhealth di d l i i h lth care. care

CourseObjectives Course Objectives

Uponsuccessfulcompletionofthiscourse,the Upon successful completion of this course the studentsshouldbeableto; 6. Describetheimportantexperimentalmethods 6 Describe the important experimental methods commonlyusedinhormonalassays.

Course

specificLearningObjectives

Specificlearningobjectives Specific learning objectives

1.Identify theorgansandtissuesoftheendocrine systemanddescribetheirgeneralmorphologicaland functionalcharacteristics. functional characteristics

2.Define thevariousformsofcellularcommunication andsignalingsystems(i.e.,endocrine,paracrine, autocrine).

Specificlearningobjectives Specific learning objectives

3. Describethevariousclassesofhormonesbothin termsoftheirstructuresandphysicochemical propertiesaswellasmechanismsofaction.

4. Recognize thetypesofcellularresponsestohormones anddefinepositiveandnegativefeedbackand describetheirroleinregulatingbloodlevelsofvarious hormones.

Specificlearningobjectives Specific learning objectives

5. Identify thetarget,representativeactions,andsecretory controlofthehormonesofthe;
5. hypothalamus, 5 hypothalamus 6. pituitarygland, 7. pancreas, 8. thyroid gland, thyroidgland, 9. parathyroidglands, 10. adrenalcortexandmedulla, p g , y , , 11. pinealgland,thymus,ovaries,andtestes.

Specificlearningobjectives Specific learning objectives

5. Define generalprincipleofgenesexpressionandpeptide hormonesynthesis,andrelatethesetocontrolof hormonesynthesisandsecretion.

6. Discuss howhormonescoordinateandintegratethe overallbodymetabolism. overall body metabolism

Specificlearningobjectives Specific learning objectives

7. Describe the specific effect of hormones action on the thespecificeffectofhormonesactiononthe majormetabolicpathwaysofcarbohydrates,lipid,amino acidandnucleotidemetabolism.

8. Defineprostaglandins,whataretheymadeof,andwhat aretheireffects?

Specificlearningobjectives Specific learning objectives

9. Recognize thecausesofdwarfism,giantism,acromegaly, diabetesinsipidus,diabetesmellitus(Type1andType ), , y , , p g , 2),cretinism,myxedema,Grave'sdisease,simplegoiter, andCushing'ssyndrome.

10. 10 Identify the common methodologies of hormone asssay thecommonmethodologiesofhormoneasssay andendocrinefunctiontests.

Specificlearningobjectives Specific learning objectives

11. Recognize theendocrinefunctionofthe; kidneys Gastrointestinaltract Gastrointestinal tract Heart Adiposetissues

Course

PBLSessions

ProblembasedLearningActivities Problem based Learning Activities

1.Hypothyroidism. 1 Hypothyroidism 2.Cushingssyndrome. 3.Diabetesmellitus. 4.Primaryinfertility. 5.5th problem to be added (discuss with Dr. problemtobeadded (discusswithDr. Elwathig)

Studentresponsibility Student responsibility

1. Studentsareexpectedtoattendlectures,tutorialsand practical/studygroupsessions.

2. Failuretomeettheminimalattendancerequirements(75%of thecourseactivities ) th ti iti )mayresultinyoubeingdeemedineligible lt i b i d d i li ibl forassessment.

3. Studentswhomissmorethan25%ofthecourseactivities 3 Students who miss more than 25% of the course activities withoutexcusewillnotbeallowedtositforthefinalexamand willbedeemedfail.

Studentresponsibility Student responsibility

1.Readandfamiliarizehim/herwiththecontentsofthe coursesyllabus.

2.Participateincourseactivitiesviaclassattendance, p discussion,andnotetaking,seminarpreparationand presentation.

3.Readandstudyassignedreadingspriortobeingtested overthematerial.

Course

Assessment

Studentassessment Student assessment

Finalexamination: accountsfor(70%)ofthetotalpoints consistsofMCQs(40%),shortnotes(20%),OSPE(10%) i f MCQ (40%) h (20%) OSPE (10%)

Thecontinuousassessments: accountsfor30%ofthetotalpoints Include mid coursetest,reports,andPBLactivities. Include midcourse test, reports, and PBL activities.

Studentassessment Student assessment

Studentsscoreswillbegradedaccordingtothefollowing scale. Score S Grade
00 00 49 F 50 50 59 C 60 60 69 B 70 70 79 B+ 80 80 100 A

Courseevaluation Course evaluation

Studentsfeedback(questionnaire). Facultycommentsandobservations. Analysisofexaminationresults.

Course

Timetable

Textbooksandresources: Text books and resources: Davidson'sPrinciplesandPracticeofMedicine20thedition(2006).NicholasA. Boon,Nicki R.Colledge andBrianR.Walker.ChurchillLivingstone. Boon Nicki R Colledge and Brian R Walker Churchill Livingstone HarpersIllustratedBiochemistry,28th edition(2009).RobertK.Murray,Victor W.Rodwell,DavidBender,KathleenM.Botham,P.AnthonyWeil,PeterJ. Kennelly.LANGEBasicScience,McGrawHill. K ll LANGE B i S i M G Hill Biochemistry:ACaseOrientedApproach,6thEdition(1990).RexMontgomery, Spector andThomasW.Conway.MosbyYearBook. BaileyandLove'sShortPracticeofSurgery24edition(2007).R.C.G.Russell, NormanWilliamsandChristopherJ.K.Bulstrode .OxfordUniversityPress. ReviewofMedicalPhysiology,22ndEdition(2005).WilliamF.Ganong.LANGE BasicScience,McGrawHill. AnAidtoClinicalSurgery,6th edition(1998).PeterR.Scott(Author),B.P. Waxman(Editor),RobinC.N.Williamson(Editor).ChurchillLivingstone. ( ), ( ) g McMinn's ColorAtlasofHumanAnatomy,4thedition(1998).P.H.Abrahams, R.T.Hutchings,S.C.Marks.MosbyYearBook.

contacts
atifkhirelsied@gmail.com
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