Generic name: Simethicon Brand name: Disflatyl Classification: GIT regulators, antiflatulents and anti-inflammation Suggested Dose: 1 tab

TID PO Mode of action: By its defoaming action, drug disperses or prevents formation of mucus surrounded gas pockets in the GI tract. Indications:

To relief of painful symptoms and pressure of excess gas in digestive tract.

Contrindications: Patients hypersensitive to drug Treating infant colic

Drug Interaction: No known drug interaction Side Effects/Adverse Effects:

GI: Nausea, vomiting, diarrhea, constipation, belching, passing of flatus

Nursing Responsibility Check the chart if the patient is hypersensitive to the drug Give the drug after meal Tell the patient to chew tablet before swallowing Advise patient to change position often and walking will help pass out flatus Report if any of the adverse effects is present

Springhouse. 2007. Nursing 2007 DRUG HANDBOOK. Philippines. Lippincott William and Wilkins. 27th edition

Generic name: dinoprostone Brand name: cerviprime Classification: oxytocin Suggested Dose: Administer entire contents of syringe into the cervical canal Mode of Action: A prostaglandin that produces strong, prompt contractions of uterine smooth muscle, possibly mediated by calcium and cAMP. Indications: F or pre-induction cervical ripening & dilatation in pregnant women at or near term w/ unfavorable induction features Contraindications: Hypersensitivity to prostaglandins. Previous caesarean section or major uterine surgery, major degree of cephalopelvic disproportion, preexisting fetal distress & difficult/traumatic labor; grand multipara, hyperactive/hypertonic uterine patterns, obstet emergencies. Placenta previa or unexplained vag bleeding during pregnancy. Vasa previa or herpes genitalia. Drug Interaction: May increase action of other oxytocic drugs but avoid using together Side Effects/Adverse Effects: Nausea, vomiting, diarrhea, intrapartum fetal heart change, uterine rupture & uterine contractile abnormalities w/ or w/o fetal distress.

Nursing Responsibility: Explain use of administration of drug to patient and family Provide privacy during administration The patient should remain recumbent for at least 30 min after administration

Advise the patient to avoid drinking alcohol since it may inhibit effectiveness of dinoprostone with high doses Treat dinoprostone inuced fever with water sponging and increased fluid intake, not with aspirin Report if any side or adverse effect is noted

http://www.mims.com/Philippines/drug/info/Cerviprime/Cerviprime%20topical%20gel

Generic name: Metoclopramide hydrochloride Brand dame: Apo-Metoclop (CAN), Maxolon, Metazolv ODT, Nu-Metoclopramide (CAN), Octamide PFS, Reglan Classification: Antidopaminergic, GI stimulant Suggested dose: 1 amp 1 hour prior to OR IVTT Mode of action: Stimulates motility of upper GI tract, increases lower esophangeal sphincter tone, and blocks dopamine recetors at the chemoreceptor trigger zone. Indication: Contraindication: Patients hypersensitive to the drug and in those with pheochromocytma or seizure disorder Patients for whom GI motility might be dangerous ( those with hemorrhhage, obstruction or perforation)

Drug interaction: Anticholinergics, opioid analgesics may antagonize GI motility effects CNS depressants may cause additive CNS effects Levodopa and metoclopramide have opposite effects on receptors; avoid using together MAO inhibitors may increase release of catecholamines in patients with hypertension Phenothiazines may increase risk of extrapyramidal effects

Adverse reaction: CNS: restlessness, anxiety, drowsiness, fatigue, lassitude, fever, depression, akathisia, insomnia, confusion, suicide ideation, seizures, neuroleptic malignant

syndrome, hallucinations, headache, dizziness, extrapyramidal symptoms, tardive dyskinesia, dystonic reactions CV: transient hypertension, hypotension, supraventricular tachycardia, bradycardia GI: nausea, bowel disorder, diarrhea GU: urinary frequency, incontinence Hematologic: neutopenia, agranulocytosis Skin: rash, urticaria Other: prolactin secretion, loss of libido

Nursing Responsibility Monitor bowel sounds Tell patient to avoid activities that require alertness for 2 hours after doses Urge patient to report persistent or serious adverse reactions promptly Advise patient to avoid drink alcohol during therapy

Springhouse. 2007. Nursing 2007 DRUG HANDBOOK. Philippines. Lippincott William and Wilkins. 27th edition