NURS 2516 Clinical Medications Worksheets

(You will need to make additional copies of these forms)

Generic Name Trade Name Classification Dose Route Time/frequency:

metronidazole Flagyl Anti-infectives, 500 mg/100mL IVPB Q 8 hrs
antiprotozoals, NS Rate of Administration (IV):
antiulcer agents Dose Range: Infuse over 60 min.
Anaerobic
infections--
Initial dose 15
mg/kg, then 7.5
mg/kg q 6-8 hr
or 500 mg q 6-8
hr (not to exceed
4 g/day).
Peak Onset Duration For IV meds
End of infusion rapid 6-8 hrs. Compatibility with IV drips and /or solutions:
Flagyl IV RTU is prediluted and ready to use (5 mg/ml).
Prefilled plastic minibags should not be used in series
connections; air embolism may result. Crystals may form
during refrigeration but will dissolve when warmed to room
temperature
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Mechanism of action and indications
(Why med ordered)
Disrupts DNA and protein synthesis in susceptible
organisms. Acute Diverticulitis.
Interactions with other patient drugs, OTC or herbal
medicines (ask patient specifically)
Manufacturer recommends discontinuing primary IV
during metronidazole infusion, Disulfiram-like reaction
may occur with alcohol ingestion
Nursing Process- Assessment
(Pre-administration assessment)
Assess patient for infection (vital signs;
appearance of wound, sputum, urine, and
stool; WBC) at beginning of and throughout
therapy, Obtain specimens for culture and
sensitivity before initiating therapy. First dose
may be given before receiving results.
Nursing Implications (what to focus on)
Contraindications/warnings/interactions
Hypersensitivity, Prefilled plastic minibags should not be used in
series connections; air embolism may result, reconstitution
requires very specific process, venting of CO2 gas may be
required.
Common side effects
Seizures, dizziness, headache, abdominal pain, anorexia, nausea
Lab value alterations caused by medicine
May alter results of serum AST, ALT, and LDH tests
Be sure to teach the patient the following about this
medication
Caution patient to avoid intake of alcoholic beverages or
preparations containing alcohol during and for at least 1 day
after treatment with metronidazole, including vaginal gel.
May cause a disulfiram-like reaction (flushing, nausea,
vomiting, headache, abdominal cramps), Inform patient that
medication may cause an unpleasant metallic taste, Advise
patient that frequent mouth rinses, good oral hygiene, and
sugarless gum or candy may minimize dry mouth. Notify
health care professional if dry mouth persists for more than 2
wk, Inform patient that medication may cause urine to turn
dark, Advise patient to consult health care professional if no
improvement in a few days or if signs and symptoms of
superinfection (black, furry overgrowth on tongue; vaginal
itching or discharge; loose or foul-smelling stools) develop
Assessment Evaluation
Why would you hold or not give Check after giving
this med? Resolution of the signs and
Monitor neurologic status during symptoms of infection. Length of
and after IV infusions. Inform time for complete resolution
physician if numbness, depends on organism and site of
paresthesia, weakness, ataxia, or infection
seizures occur, hypersensitivity