6th Congress, Beijing, China

May 5-7, 2012

General Information
Welcome to the AOHUPO 6th Congress. All congress activities and exhibit booths are in the Convention Area of the China National Convention Center. Registration and Information The registration desk is located on the 4th floor of the Convention Area (Entrance C1 of the CNCC). Opening Time: May 4 08:30 - 21:00 May 5 08:30 - 18:50 May 6 08:30 - 17:40 May 7 08:30 - 18:20 Registered Delegates are Entitled to: Opening Ceremony, Welcome Reception/Banquet and Closing Ceremony Attendance to Sessions Entrance to Exhibition All Congress Documents Coffee Breaks Forbidden City Tour Name Badges and Tickets For security purposes, delegates and exhibitors must wear their name badges at all times during the congress. Entrance to the meeting room will be limited to badge holders only. Tickets for social events and excursions will be issued to delegates who have booked for these events. Please present your tickets at these events and excursions. Abstracts The abstracts are available on a USB stick which is included in the registration package for registered delegates. Co ng r es s I n f o r m a t io n Program Changes The organisers cannot accept liability for any changes in the program due to external or unforeseen circumstances. Oral Presentations Only LCD computer projectors are used for oral sessions. The congress session computers are running Windows XP and PowerPoint 2007. Speakers must go to the Speaker Ready Room at least one day prior to their talks to load their powerpoints onto the congress computers. The Speaker Ready Room is Room 409, 4th Floor. The room will keep opening with a technician present during the following time slots: May 4 14:30 - 17:30 May 5 08:30 - 18:50 May 6 08:30 - 17:40 May 7 08:30 - 12:10 Poster Presentations Refer to the poster numbers in this program for board assignments. Authors are expected to supply scotch tape to mount

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their posters. Posters must be in place by 16:30 on May 5 at the Poster Area and removed at 17:40 on May 7. To assure all attendees to have time for viewing posters, please do not remove posters ahead of the designed time. All the posters have the opportunities to join the competition of the AOHUPO 2012 Excellent Poster Award. 30 posters will be awarded in the Closing Ceremony. Each award will equal RMB 500. Poster presentation time: May 6 12:10 - 14:00 May 7 12:10 - 14:00 Duplication, Recording Without permission from authors, taking photographs, audio-taping, video-recording, digital taping and any other form of duplication are strictly prohibited in the session rooms and poster areas. Mobile Phones Participants are kindly requested to turn off their cell phones or keep the cell phones in vibration state when entering the congress rooms and in the poster area. Smoking Policy In the China National Convention Center, smoking is prohibited. Smoking is only permitted in a few designated areas outside the building. Internet Access A free Internet room will be opened during the congress hours in the Plenary Hall A-Po. Catering Some specified meal tickets are included in the registration package for registered delegates. Please refer to the table below for the location and times. Please note that our generous sponsors will also provide meals at the Industry Workshops on May 6-7 with pre-assignment at their booths. May 5 Lunch Dinner At delegates own expense Ballroom A, 1st Floor 19:00 - 21:00 --May 6 Exhibition Hall 6, B1 Floor 12:10 - 13:30 Nine Dynasty Restaurant 17:40 - 20:00 (Invited) L4 Lobby, 4th Floor Coffee Break 09:50 - 10:10 16:00 - 16:20 STAFF Brigade A team of enthusiastic students will be at your service. During the congress hours, they will provide hospitality support and steward services. They will also serve in most of the meeting rooms as technical assistants and can be easily recognized by their shirts of STAFF. Time Beijing is 8 hours ahead of Greenwich Mean Time. May 7 Exhibition Hall 5, B1 Floor 12:10 - 13:30 Co ng r es s At delegates own expense L4 Lobby, 4th Floor 09:50 - 10:10 16:00 - 16:20

I n f o r m a t io n

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6th Congress, Beijing, China

May 5-7, 2012

Weather May is the best month for weather condition in Beijing. Typically, it is neither hot nor cold just the perfect time to stay and visit in Beijing and elsewhere in China. The average temperature in Beijing in May is 20.The average highest temperature is 25 and the average lowest temperature is 17. Water It is not recommended to directly drink the water from the tap in your hotel room or at the congress area. If you want to drink cold water, it is best to order or buy bottled water, mineral or distilled water. Hotels generally provide an electrically heated kettle to boil water from the tap in your room. Some hotels also provide a special tap in the lavatory that delivers a flow of purified water for drinking. This advice also applies to your pre-congress or post-congress travel in other cities in China. Voltage, Socket and Plugs The electrical current in China is 220-volts, 50HzA/C. Hotels generally provide wall sockets in every room, accommodating both the standard Flat blade attachment plug (Type A)and common Oblique flat blades with ground(inverted V) plug (Type I) as well as the not-so-common Round pin attachment plug (Type C)as shown in following photographs.

Wall socket Currency

Type A plug

Type I plug

Type C plug

The local currency is the RMB. Visa and MasterCard are accepted at the Registration Desk. Foreign currency will not be accepted. You are requested to pay with cash in RMB or credit card. The amount debited from your account will vary due to fluctuations in the exchange rate. There is normally a 4% additional bank charge. Participants can exchange their currencies at airports, major hotels and banks in China. The exchange rate will be given daily by the Bank of China. Currently, 1USD can be exchanged for about 6.3 RMB yuan. All currency exchange receipts should be saved in case participants want to exchange RMB back to their own currency. Banks may demand to see the original exchange receipt. Emergencies If you or any other delegate is unwell, an accident or any other emergency occurs, while at the China National Convention Center, please contact the Registration Desk or any staff member. Lost Property If you see any unattended parcel, please report to one of the congress staff members. If you lose anything at the China National Convention Center, please enquire at the Registration Desk. Insurance The congress organisers recommend participants to posses travel, property medical or other necessary insurances before coming to China. The 6th AOHUPO Congress Organisers cannot be held responsible for the costs resulting from personal accidents or property loss during the congress. Co ng r es s I n f o r m a t io n

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Hotlines Phone number 110 Police 114 Local Telephone Number Inquiry 117 Time Inquiry 119 Fire 120 Ambulance 121 Weather Forecast 122 Traffic Police How to Reach the China National Convention Center Address: No.7 Tianchen East Road, Chaoyang District, Beijing China Subway line 8 Olympic Green direct entrance CNCC (Exit ADE), about 26km to Beijing Capital International Airport, 25 minutes. Bus: 328484628630419913379 get off at Walinankou Station. A) Beijing Railway Station - China National Convention Center Subway line 2: Beijing Station-Yonghegong L a m a Te m p l e S t a t i o n , t r a n s f e r l i n e 5 t o Huixinxijie Nankou Station, transfer line 10 to Beitucheng Station, finally transfer line 8 to Olympic Green Station. B) Beijing West Railway Station - China National Convention Center Subway line 1: Military Museum-Fuxinmen Station, transfer line 2 to Yonghegong Lama Temple Station, transfer line 5 to Huixinxijie Nankou Station, transfer line 10 to Beitucheng Station, finally transfer line 8 to Olympic Green Station. C) Beijing South Railway Station - China National Convention Center Subway line 4: Fuxinmen Station, transfer line 10 to Beitucheng Station, finally transfer line 8 to Olympic Green Station. Co ng r es s I n f o r m a t io n

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6th Congress, Beijing, China

May 5-7, 2012

Place Card

Please take me to the China National Convention Center

Please take me to the China National Convention Center Grand Hotel

Co ng r es s I n f o r m a t io n

Please take me to the InterContinental Beijing Beichen

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Congress Agenda
Time Program Venue

May 4, 2012
08:30-21:00 08:30-17:20 Registration International Interactome Initiative (I3) Workshop L4 Olympic Green Foyer Room 401

May 5, 2012
08:00-09:50 08:30-16:30 09:15-16:15 10:00-16:15 16:30-17:00 17:00-18:20 18:20-18:50 19:00-21:00 2nd AOHUPO hESC-MPI Workshop Registration 5 C-HPP Consortium Workshop Education & Training Workshop Opening Ceremony Plenary Lecture 10 Anniversary for CNHUPO & Release of Special Book Liver Proteome Welcome Reception/Banquet Ballroom A
th th

Room 401 L4 Olympic Green Foyer Room 402AB Room 301AB

Plenary Hall A

May 6, 2012
08:30-09:50 09:50-10:10 10:10-12:10 Plenary Lecture Coffee Break Plenary Lecture Industrial Workshop: ThermoFisher 12:10-14:00 The Impact of High-Performance Mass Spectrometry in Biology Research Posters Exhibitions 12:30-13:30 AOHUPO Council Meeting Parallel Sessions Session 1: Advancement of Biomarkers Research for Disease and Drugs 14:00-16:00 Session 2: Biomarkers of Disease and Personalized Medicine Session 3: Proteomics of Model Organisms and Other Plants & Microorganisms Session 4: Chemical Proteomics and Drug Discovery 16:00-16:20 16:20-17:40 17:40-20:00 Coffee Break Plenary Lecture Expert Hospitality Dinner (INVITED ONLY) Plenary Hall A Auditorium Room 402AB Room 301AB L4 Lobby Plenary Hall A Nine Dynasty Restaurant Plenary Hall A L4 Lobby Plenary Hall A Auditorium Plenary Hall A-Po L4 Lobby Room 401

Co ng r e ss P r o gr a m s & Ev e n t s

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6th Congress, Beijing, China

May 5-7, 2012

Congress Agenda
Time May 7, 2012
08:30-09:50 09:50-10:10 Plenary Lecture Coffee Break Parallel Sessions 10:10-12:10 Session 5: Post-translational Modifications Session 6: Glycoproteins and Glycans: Structure, Function and Applications Session 7: Proteomics and Clinical Application Industrial Workshop: AB SCIEX Plenary Hall A Auditorium Room 402AB Auditorum Plenary Hall A-Po L4 Lobby Plenary Hall A L4 Lobby

Program

Venue

12:10-14:00

Pushing the Limits in Proteomics Workflows Posters Exhibitions Parallel Sessions

14:00-16:00

Session 8: Quantitative and Targeted Proteomics and System Biology Session 9: Proteomics: New Approaches and Novel Techniques

Plenary Hall A Auditorium Room 402AB L4 Lobby Plenary Hall A

14:00-16:05 16:00-16:20 16:20-17:40 17:40-18:10

Session 10: Bioinformatics: Databases, Post-translation Modifications, Quantification and Validation Coffee Break Plenary Lecture Closing Ceremony

May 8, 2012
08:30-12:10 Tour Forbidden City

Co ng r e ss P r o gr a m s & Ev e n t s

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Plenary Lecture Program

Time Speaker and Title

May 5, 2012
Chair: Fuchu He, Beijing Proteome Research Center; Beijing Institute of Radiation Medicine, China 17:00-17:40 Aaron Ciechanover Faculty of Medicine, Technion-Israel Institute of Technology, Israel Title: Why Our Proteins Have to Die so We shall Live or the Ubiquitin Proteolytic System - From Basic Mechanisms thru Human Diseases and onto Drug Development 17:40-18:20 Xiaodong Wang National Institute of Biological Sciences, China Title: Understanding Cell Death

May 6, 2012
Chair: Kazuyuki Nakamura, Yamaguchi University Graduate School of Medicine, Japan 08:30-09:10 Daniel W. Chan Johns Hopkins Medical Institutions, USA Title: Translating Proteomics into the Clinical Laboratory: The Future Is Now 09:10-09:50 Kunliang Guan Fudan University, China; University of California, San Diego, USA Title: Protein Lysine Acetylation in Metabolism Regulation Chair: Yukui Zhang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China 10:10-10:50 Leroy Hood Institute for Systems Biology, USA Title: Systems Biology, Transformational Technologies and the Emergence of Proactive P4 Medicine 10:50-11:30 Ruedi Aebersold ETH Zurich and University of Zurich, Switzerland Title: Mass Spectrometry Based Proteomics and Systems Biology 11:30-12:10 Pierre Legrain Ecole Polytechnique, France Title: From Genes and Proteins to Human Being: Can We Revisit the Role of Heredity? Co ng r e ss P r o gr a m s & Ev e n t s

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6th Congress, Beijing, China

May 5-7, 2012

Plenary Lecture Program

Time
May 6, 2012
Chair: Richard J. Simpson, La Trobe University, Australia 16:20-17:00 Gilbert S. Omenn University of Michigan, USA Title: Role of the HUPO Human Proteome Project in Advancing the Field of Proteomics 17:00-17:40 Young-Ki Paik Yonsei Proteome Research Center, Korea Title: A Chromosome-Centric Human Proteome Project to Characterize the Sets of Proteins Encoded in the Genome

Speaker and Title

May 7, 2012
Chair: Zihe Rao, Tsinghua University, China 08:30-09:10 Tom L. Blundell University of Cambridge, UK Title: The Structural Proteome and Drug Discovery: Chemical Tools for Targeting Protein Networks 09:10-09:50 John R. Yates The Scripps Research Institute, USA Title: Protein Quantitation Using Stable Isotope Labeling in Mammals Chair: Young-Ki Paik, Yonsei Proteome Research Center, Korea 16:20-17:00 Guangbiao Zhou Institute of Zoology, Chinese Academy of Sciences, China Zhu Chen Shanghai Jiao Tong University School of Medicine; Minister of Health, China Title: Synergistic Targeting Therapies against Oncoproteins for Acute Myeloid Leukemia 17:00-17:40 Denis Hochstrasser Geneva University Hospital, Switzerland Title: Clinical Mass Spectrometry & Proteomics Co ng r es s P r og r a m s & E ve n t s

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Parallel Session Programs

14:00-16:00, May 6, 2012 Plenary Hall A Session 1: Advancement of Biomarkers Research for Disease and Drugs
Chairs: Maxey C.M. Chung & Terence C.W. Poon

Time
14:00-14:20

Speaker and Title

Maxey C.M. Chung National University of Singapore, Singapore Title: Mining the Gastric Fluid and Gastric Secretome for Potential Diagnostic Markers for the Detection of Early Gastric Cancer

14:20-14:40

Gyrgy Marko-Varga Lund University, Sweden Title: Biomarker Diagnostics Developments for Targeted Drug Treatments

14:40-15:00

Terence C.W. Poon The Chinese University of Hong Kong, Hong Kong SAR, China Title: Serum N-Glycomic Fingerprint for the Diagnosis of Liver Fibrosis and Liver Cirrhosis in Patients with Chronic Hepatitis B Infection before and after Antiviral Treatment

15:00-15:20

Siqi Liu Beijing Institute of Genomics, Chinese Academy of Sciences, China Title: The Cascade Changes of Functional Molecules in Gastric Cancer Cells: Mutation Linkage of Genomics and Proteomics

15:20-15:40

Chan-Wha Kim Korea University, Korea Title: Transgelin Promotes Migration and Invasion of Cancer Stem Cells

Co ng r es s

15:40-16:00

Canhua Huang West China Hospital, Sichuan University, China Title: Proteomic Annotation of the Metabolic and Oxidative Stresses in Tumor Initiation and Progression

P r og r a m s & E ve n t s

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6th Congress, Beijing, China

May 5-7, 2012

Parallel Session Programs

14:00-16:00, May 6, 2012 Auditorium Session 2: Biomarkers of Disease and Personalized Medicine
Chairs: Mark Baker & Jisnuson Svasti

Time
14:00-14:20

Speaker and Title

Mark Baker Macquarie University, Australia Title: Membrane Proteomics: Peeking into the Pandoras Box of Cancer Metastasis

14:20-14:40

Xuemin Zhang National Center of Biomedical Analysis, China Title: The Mechanistic Linkage between Inflammation and Tumorigenesis

14:40-15:00

Kazuyuki Nakamura Yamaguchi University Graduate School of Medicine, Japan Title: Disease Biomarker Discovery: HSP27 for Diagnostics and Therapeutics of Pancreatic Cancer

15:00-15:20

Dacheng He Beijing Normal University, China Title: Chronological Protein Expression in Liver Regeneration

15:20-15:40

Guangyan Cai Chinese PLA General Hospital, China Title: Characterization of Glomerular Diseases Using Proteomic Analysis Methods

15:40-16:00

Xianchun Wang Hunan Normal University, China Title: Identification and Validation of Rab3A as a New Interacting Partner of Synaptotagmin I: Implications in the Regulation of Synaptic Vesicle Exocytosis

C on gr es s Pr ogr am s & Ev en t s

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14:00-16:00, May 6, 2012 Room 402AB Session 3: Proteomics of Model Organisms and Other Plants & Microorganisms
Chairs: Ravi Sirdeshmukh & Ghasem Hosseini Salekdeh

Time
14:00-14:20

Speaker and Title

Ghasem Hosseini Salekdeh Royan Institute for Stem Cell Biology and Technology, Iran Title: Quantitative Proteome and Transcriptome Analysis of Human Embryonic Stem Cells Differentiation to Neural Cells

14:20-14:40

Yhong-Hee Shim Konkuk University, Korea Title: Proteomic Analysis of Sperm Proteins Controlled by IFE-1, A germline-specific Isoform of eIF4E, in C. elegans

14:40-15:00

Xuanxian Peng Yat-sen Sun University, China Title: Proteomics Mechanisms of Bacterial Antibiotic Resistances

15:00-15:20

Vengatesen Thiyagarajan The University of Hong Kong, Hong Kong SAR, China Title: Marine Environmental Proteomics and Its Applications for Climate Change

15:20-15:40

Jahanbakhsh-Godehkahriz University of MohagheghArdabili, Iran Title: Proteomic Analysis of Porphobilinogen (PBG) Deaminase& 3-oxoacyl-[acyl-carrier-protein] Synthase I (KAS I) in Cheyenne Winter Wheat under Prolonged Low temperature C on gr es s

15:40-16:00

Yingchun Wang Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China Title: Proteomic Identification of Slr0110-regulated Proteins that are Necessary for Heterotrophic Growth of Synechocystis sp. PCC6803

Pr ogr am s & Ev en t s

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6th Congress, Beijing, China

May 5-7, 2012

Parallel Session Programs

14:00-16:00, May 6, 2012 Room 301AB Session 4: Chemical Proteomics and Drug Discovery
Chairs: Ho Jeong Kwon & Qingyu He

Time
14:00-14:25

Speaker and Title

Guoqiang Chen Shanghai Jiao Tong University School of Medicine, China Title: Natural Product Adenanthin Specifically Targets Peroxiredoxin I/II for Its Anti-leukemic Activities

14:25-14:50

Ho Jeong Kwon Yonsei University, Korea Title: Chemical Proteomics Based Target Identification of a Natural Anti-angiogenic Small Molecule

14:50-15:15

Qingyu He College of Life Science and Technology, Jinan University, China Title: Mitochondria Are a Major Target of the Anti-Cancer Agents Derived from Traditional Chinese Medicine (TCM)

15:15-15:30

Lixin Zhang Institute of Microbiology, Chinese Academy of Sciences, China Title: Bioprospecting Natural Products for Potential Anti-Infective Drugs

15:30-15:45 C on gr es s Pr ogr am s & Ev en t s

Lianghai Hu College of Life Science, Jilin University, China Title: Chemical Proteomics-based Approach for Drug Target Discovery in Living Systems

15:45-16:00

Fuyi Wang Institute of Chemistry, Chinese Academy of Sciences, China Title: Organometallic Ruthenium Complexes Inhibit the Enzymatic Activity of Protein Tyrosine Phosphatase 1B via Coordination to and Subsequently Induced Oxidation of the Active Thiols

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10:10-12:10, May 7, 2012 Plenary Hall A Session 5: Post-translational Modifications

Chairs: Hisashi Hirano & Jun Qin

Time
10:10-10:30

Speaker and Title

Hisashi Hirano Yokohama City University, Japan Title: Functional Analysis of Co- and Post-translational Modifications in Large Protein Complexes

10:30-10:50

Jun Qin Beijing Proteome Research Center, China Title: Building a Proteomics Research Facility in China

10:50-11:10

Peipei Ping University of California at Los Angeles, USA Title: PTM Analyses of Functional Proteomes: Linking Molecular Modifications to Cardiac Phenotypes

11:10-11:30

Jiarui Wu Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China Title: Molecular Bases for Population Variation: from SNP to SAP

11:30-11:50

Yu-Ju Chen Institute of Chemistry, Academia Sinica, Chinese Taipei Title: A Simple Label-free Strategy towards Comprehensive Tissue Membrane Proteomics and Post-translational Modificome C on gr es s

11:50-12:10

Shimin Zhao Fudan University, China Title: Meatbolites Regulate Epigenetics and Signaling

Pr ogr am s & Ev en t s

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6th Congress, Beijing, China

May 5-7, 2012

Parallel Session Programs

10:10-12:10, May 7, 2012 Auditorium Session 6: Glycoproteins and Glycans: Structure, Function and Applications
Chairs: Hisashi Narimatsu & Haojie Lu

Time
10:10-10:30

Speaker and Title

Hisashi Narimatsu Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology, Japan Title: Large-scale Identification of N-glycosylated Proteins of Mouse Tissues and Construction of a Glycoprotein Database, GlycoProtDB

10:30-10:50

Hyun Joo An ChungNam National University, Korea Title: Human Cell Surface Glycan Mapping Using Mass Spectrometry

10:50-11:10

Kay-Hooi Khoo Institute of Biological Chemistry, Academia Sinica, Chinese Taipei Title: Technical Developments towards Realizing Shotgun Glycoproteomics for Protein Site-specific Glycosylation Mapping

11:10-11:30

Yinkun Liu Fudan University, China Title: Glyco-biomarker Screening and Further Application in Hepatopathy

11:30-11:50

Wonryeon Cho Wonkwang University, Korea Title: Targeted Glycoproteomics for Cancer Biomarker Discovery

C on gr es s Pr ogr am s & Ev en t s

11:50-12:10

Wan Huang The Fourth Military Medical University, China Title: Modulation of the CD147-Induced Matrix Metalloproteinases Activity: The Role of CD147 N-Glycosylation

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10:10-12:10, May 7, 2012 Room 402AB Session 7: Proteomics and Clinical Application
Chairs: William S. Hancock & Zhinan Chen

Time
10:10-10:35

Speaker and Title

William S. Hancock Northeastern University, USA Title: Chromosome 17 as Part of the C-HPP Initiative and the Study of Oncogene (ERBB2 and EGFR) Driven Cancer

10:35-11:00

Zhinan Chen The Fourth Military Medical University, China Title: Biosignatures Network and Its Novel Target Drugs

11:00-11:25

Nikhat Ahmed Siddiqui University of Karachi, Pakistan Title: Alzheimers Disease Proteomics---at the Crossroads between Promises and Problems

11:25-11:40

Tadashi Kondo National Cancer Center Research Institute, Japan Title: Proteomics for Biomarker Development to Personalized Medicine

11:40-11:55

Archakov Alexander Russian Academy of Medical Sciences, Russia Title: Three Bottlenecks in Proteomics C on gr es s

11:55-12:10

Jau-Song Yu Chang Gung University, Chinese Taipei Title: Multiplexed Quantification of 63 Proteins in Human Urine by Multiple Reaction Monitoringbased Mass Spectrometry for Discovery of Potential Bladder Cancer Biomarkers

Pr ogr am s & Ev en t s

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6th Congress, Beijing, China

May 5-7, 2012

Parallel Session Programs

14:00-16:00, May 7, 2012 Plenary Hall A Session 8: Quantitative and Targeted Proteomics and System Biology
Chairs: Visith Thongboonkerd & Xiaohong Qian

Time
14:00-14:20

Speaker and Title

Catherine Costello Boston University School of Medicine, USA Title: Determination of Differential Phosphorylation and Biological Responses to EGF and Nucleotides

14:20-14:40

Xiaohong Qian Beijing Proteome Research Center; Beijing Institute of Radiation Medicine, China Title: Biological Mass Spectrometry Based Strategies for Qualitative and Quantitative Analysis of Core Fucosylated Glycoproteins

14:40-15:00

Visith Thongboonkerd Mahidol University, Thailand Title: Applications of Proteomics to Kidney Stone Disease

15:00-15:20

Hanfa Zou Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China Title: Method Development for Qualitative and Quantitative Phosphoproteome

15:20-15:40

Peng Xie Chongqing Medical University, China Title: The Proteomics and Metabonomics Research of Major Depressive Disorder

C on gr es s Pr ogr am s & Ev en t s

15:40-16:00

Jianke Li Chinese Academy of Agricultural Sciences, China Title: Comparative Analysis of Nuclear Proteomes between Honeybee (Apis Mellifera L.) Queen and Worker Larvae

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14:00-16:00, May 7, 2012 Auditorium Session 9: Proteomics: New Approaches and Novel Techniques
Chairs: Bill Jordan & Ajay Kohli

Time
14:00-14:20

Speaker and Title

Bill Jordan Victoria University of Wellington, New Zealand Title: Membrane Proteomes: Analysis and Metabolic Functions

14:20-14:40

Richard J. Simpson La Trobe University, Australia Title: Purification and Characterisation of Two Discrete Exosome Populations from the Human Colon Cancer LIM1863 Cell Line

14:40-15:00

Yukui Zhang Dalian Institute of Chemical Physics, Chinese Academy of Sciences, China Title: Novel Materials, Methods and Platforms for Separation, Identification and Quantitation of Proteomes

15:00-15:20

Eugene N. Nikolaev Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences, Russia Title: The New Possibilities of FT ICR in Very High Resolution Mass Spectrometry of Peptides and Proteins. Fine Structure of Peptides Mass Spectra and Isotopic Resolution of Near 200kDa Proteins

15:20-15:40

Mengqiu Dong National Institute of Biological Sciences, China Title: An Integrated High-throughput Workflow for Identification of Crosslinked Peptides from Complex Samples

C on gr es s

15:40-16:00

Rao V. L. Papineni Carestream Health, Inc., USA Title: Non Invasive Functional Molecular Imaging-Illuminate the Myeloperoxidase Enzyme Activity During Ovarian Cancer Mouse Model Tumorigenesis

Pr ogr am s & Ev en t s

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6th Congress, Beijing, China

May 5-7, 2012

14:00-16:05, May 7, 2012 Room 402AB Session 10: Bioinformatics: Databases, Post-translation Modifications, Quantification and Validation
Chairs: Pierre-Alain Binz & Weimin Zhu

Time
14:00-14:25

Speaker and Title

Pierre-Alain Binz Swiss Institute of Bioinformatics, Switzerland Title: Believe in Proteomics Results: On the Need for Data and Information Sharing

14:25-14:50

Weimin Zhu Taicang Institute of Life Science Information, China Title: Stories of Peptide/Protein Sequences Protein Annotations

14:50-15:05

Lisitsa Andrey Institute of Biomedical Chemistry, Russia Title: Knowledgebase for Single Chromosome Proteins

15:05-15:20

Hongwei Xie National University of Defense Technology, China Title: Share the ppb Level Accuracy in Common LC-MS Analysis

15:20-15:35

Juan Pablo Albar National Center for Biotechnology CSIC, Spain Title: Automatic Reporting and Reproducibility Analysis Using the ProteoRed MIAPE extractor Tool

C on gr es s Pr ogr am s & Ev en t s

15:35-15:50

Dong Li Beijing Proteome Research Center, China Title: Bioinformatics for Interactomics: Knowledge Mining from Large-scale Protein-protein Interaction Networks

15:50-16:05

Will Dracup Nonlinear Dynamics Ltd., UK Title: A Radical New Approach to Proteomic Experiment Design and Execution that Maximises the Likelihood of Clinical Impact

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Workshop Programs
International Interactome Initiative (I3) Workshop
Time: 08:30-17:20, May 4, 2012 Venue: Room 401, China National Convention Center Chairs: Benoit Coulombe, Xiaoming Yang and Jun Qin

Schedule:
08:30-08:35 08:35-08:45 Greetings from the Local Host: Jun Qin, BPRC, China Introduction to International Interactome Initiative (I3) on Cardiometabolic Diseases Benoit Coulombe, Institut de Recherches Cliniques de Montral, Canada

Part 1
08:45-09:10

Chair: Benoit Coulombe

Mapping and Systematic Monitoring of the Protein Interactome Underlying Cardiometabolic Diseases to Accelerate Biomarker Discovery and Personalized Drug Treatment Global introduction and experimental approach to interactome mapping Benoit Coulombe, Institut de Recherches Cliniques de Montral, Canada

09:10-09:35 09:35-10:00 10:00-10:25 10:25-10:35

Bioinformatics and Computational Analysis of Protein Interaction Data Mathieu Blanchette, McGill University, Canada Mass Spectrometry-SRM of Biomarkers in Clinical Samples Denis Faubert, Institut de Recherches Cliniques de Montral, Canada Clinical Aspects of Biomarker Discovery in Type 2 Diabetes Marie-Soleil Gauthier, Institut de Recherches Cliniques de Montral, Canada Coffee Break

Part 2
10:35-11:00 11:00-11:25 11:25-11:50 11:50-13:00 13:00-13:25 13:25-13:50

Chair: Xiaoming Yang

Analysis of Mammalian Endogenous Complexome Jun Qin, Beijing Proteome Research Center, China Protein-protein Interactions between Host and Yersinia pestis Ruifu Yang, Beijing Institute of Microbiology and Epidemiology, China Study on Mitochondrial Intermembrane Space Protein Network Miao Yu, Beijing Institute of Radiation Medicine, China Lunch and Rest Transcription Factor Interactome Network in Human Hematopoietic Stem Cell Changyan Li, Beijing Institute of Radiation Medicine, China Functional Research of Human Liver Protein-protein Interaction Network Jian Wang, Beijing Proteome Research Center, China

C on gr es s Pr ogr am s & Ev en t s

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6th Congress, Beijing, China

May 5-7, 2012

Part 3
13:50-14:15

Chair: Jun Qin

Protein Interactome Analysis Reveals HIP-55/14-3-3 Complex as a Potential Regulator of Tumorigenesis in Non-small Cell Lung Cancer Zijian Li, Peking University Third Hospital, China

14:15-14:40

MeCP2 Is Regulated by Phosphorylation and Does Not Stably Associate with SWI/SNF ChromatinRemodeling Complex Keping Hu, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, China

14:40-15:05

A Novel Histone H4 Binding Activity and Transcriptional Regulatory Function for Signal Recognition Particle Subunits SRP68 and SRP72 Jiemin Weng, East China Normal University, China

15:05-15:30 15:30-15:55

Protein Phosphorylation and Regulatory Swith Yixue Li, Shanghai Information Center for Life Science, CAS, China Bioinformatics for I3: Construction, Data Management and Knowledge Mmining for the Large-scale Proteinprotein Interaction Datasets Dong Li, Beijing Proteome Research Center, China

15:55-16:20 16:20-16:35 16:35-17:20 18:00-20:00

High-Performance Mass Spectrometry as a Tool for Modular Cell Biology Andreas FR Huhmer, Thermo Fisher Scientific Coffee Break Discussion and Future Plan Chairs: Benoit Coulombe, Xiaoming Yang and Jun Qin Dinner and Further Discussion (INVITED ONLY)

C on gr es s Pr ogr am s & Ev en t s

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2nd AOHUPO hESC-MPI Workshop

(AOHUPO human Embryonic Stem Cell-Membrane Proteome Initiative)
Time: 08:00-09:50, May 5, 2012 Venue: Room 401, China National Convention Center Chairs: Ghasem Hosseini Salekdeh, Yu-Ju Chen Host: Ying Jiang Theme: Current Status and Future Direction of AOHUPO hESC-MPI

Schedule:
08:00-08:05 08:05-08:15 08:15-08:30 08:30-08:40 08:40-08:50 Greetings from the Local Host Ying Jiang, Beijing Proteome Research Center, China Brief Summary of the Multi-lab Data for the AOHUPO MPI Bill Jordan, Chair of AOHUPO MPI, Victoria University of Wellington, New Zealand Proteomics of Undifferentiated & Neuronally-differentiating Huntington Disease hESCs Mark Baker, Macquarie University, Australia Sample Preperation for Plasma Membrane Proteome Analysis by Mass Spectrometry Songping Liang, Hunan Normal University, China An Overview of AOHUPO hESC-MPI Ghasem Hosseini Salekdeh, AOHUPO hESC-MPI, Royan Institute for Stem Cell Biology and Technology, Iran 08:50-09:05 09:05-09:15 09:15-09:25 09:25-09:35 09:35-09:50 AOHUPO hESC MPI Sample Preparation Yu-Ju Chen, Co-chair of AOHUPO hESC-MPI, Academia Sinica, Chinese Taipei Proteomic Analysis on AOHUPO hESC MPI Sample Ying Jiang, Beijing Proteome Research Center, China Brief Summary Report of Mitochondria Sample Run Maxey C.M. Chung, National University of Singapore, Singapore Integration of AOHUPO hESC MPI data Yu-Ju Chen, Co-chair of AOHUPO hESC-MPI, Academia Sinica, Chinese Taipei Discussion C on gr es s Pr ogr am s & Ev en t s

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6th Congress, Beijing, China

May 5-7, 2012

5th C-HPP Consortium Workshop

(The Chromosome-Centric Human Proteome Project)
Time: 09:15-16:15, May 5, 2012 Venue: Room 402AB, China National Convention Center Chairs: Young-Ki Paik, William S. Hancock and Gyrgy Marko-Varga Host: Fuchu He Theme: Setting out the Standard Guidelines and the Milestones for the C-HPP Goals: Completion of the Organisation and Working Formats for the C-HPP

Schedule:
09:15-09:20 09:20-09:35 09:35-09:45 09:45-10:15 10:15-11:45 Greetings from the Local Host: Fuchu He, BPRC, China Strategic Directions for the C-HPP as Part of the Overall Human Proteome Project (HPP) Gil Omenn, Chair of HPP Consortium, University of Michigan, USA Update on the Progress of the C-HPP Consortium Young-Ki Paik, Chair of C-HPP Consortium, YPRC, Korea Genetic Variants from Next Generation, Whole Genome DNA Sequencing Datasets: A 1000 Genomes Perspective Charles Lee, Co-Chair of 1000 Genome Project, Harvard Medical School, USA Key Issues on the Execution of the C-HPP Guidelines (e.g., Bioinformatics) Co-Chaired by William S. Hancock, Gil Omenn and Pierre Legrain Consensus on the governance and completion of the structure (Committees, WG etc.) Data Management (to address the questions how the data generated in the specific chromosome projects will be transferred to the three pillar databases, what quality criteria should be applied etc.) -see also C-HPP guideline paper (Paik et al., 2012, JPR, 11(4):2005-13) General Experimental Procedures Resources: Abs and Reagents (Eduardo Nice and more) Bioinformatics and Web Portal (Seul-Ki Jeong, Robert J. A. Goode,, more) Coordination with B/D-HPP, HPP Resource Pillars, and Other HUPO Initiatives (HAI, PSI etc) 11:45-13:45 11:45-13:45 Luncheon Symposium Progress Report on Each Chromosome Team C on gr es s Pr ogr am s & Ev en t s Chr 7 (ANZ)

Part I: Chair, Gyrgy Marko-Varga, Co-Chair of C-HPP Consortium, Sweden

Chr 1 (China) CAPE (Chromosome-Assembled Proteome Encyclopedia) and Its Highlight with Chromosomes 1 and 8 Fuchu He, BPRC, China Chr 2 (Switzerland) Pierre-Alain Binz, SIB, Switzerland Chr 3 (Japan) Chromome 3 and the Disease-Related Proteins Discovered Using Laser-Microdissected (LMD) Lung- Carcinoma FFPE tissues Toshihide Nishimura/Hiromasa Tojo/Kazuyuki Nakamura, Tokyo Medical University, Japan Down Under Chromosome 7 Mark Baker, Macquarie University, Australia and Bill Jordan, Victoria University of Wellington, New Zealand

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Part II: Chair, Pierre Legrain, Ecole Polytechnique, France

Chr 11 (Korea) Chr 12 (Thailand) Chr 13 (Korea) Chr 16 (Spain) Human Proteome Project for Chromosome 11 in Human Brain Tissue Jong Shin Yoo, KBSI, Korea Introduction of Chromosome 12 Initiative Visith Thongboonkerd, Mahidol University, Thailand Progress on Chr 13 HPP Young-Ki Paik, YPRC, Korea Spanish HPP Consortium: Current Developments on the Characterization of the Proteins Encoded by the Chromosome 16 Juan Pablo Albar, Madrid, Spain Chr 17 (USA) Progress on Chr 17 HPP William S. Hancock, Northeastern University, USA

Part III: Chair, Fuchu He, BPRC, China

Chr-18 (Russia) Chr-19 (Sweden) Chr-X (Japan) Chr-Y (Iran) Proteome of 18th Chromosome in Plasma, Liver and HepG2 Cells Investigated by SRM/MRMs Alexander Archakov, RAMS, Russia Progress Report from Chromosome 19 Gyrgy Marko-Varga, Lund University, Sweden Japan Chromosome X Project (JCXP) Consortium: To Do and Done Tadashi Yamamoto, Niigata University, Japan Human Y Chromosome Proteome Project: A Genomics and Proteomics Perspective Ghasem Hosseini Salekdeh, Royan Institute for Stem Cell Biology and Technology, Iran (Only three teams of Chr 6, 14, 21 will be missing from this workshop) 13:45-14:05 14:05-14:45 14:45-15:55 Coffee Break Funding issues: by Gyrgy Marko-Varga and Pierre Legrain Grant Situation (any granting agency for C-HPP) Progress Reports and Publications: by William S. Hancock and Young-Ki Paik Progress Report Forms (standard form) (To be distributed later) Special Issue Publication: Jan 2013 Issue of JPR General guidelines for manuscript preparation and submission Deadline of Submission: September 30, 2012 15:55-16:15 Upcoming Boston Congress and Strategy for Session Organisation Gil Omenn, Young-Ki Paik and William S. Hancock * Remarks: This meeting also functions as the 1st Principal Investigator Council (PIC) meeting of the C-HPP Consortium unless otherwise noted. Any decisions on the major policies and governance on the C-HPP made from this meeting would be recorded as the PICs decisions. Inquiry: For Logistics and Travel Arrangement, For Programs and Presentations, Contact: Ping Xu, xupingghy@gmail.com Contact: Young-Ki Paik, paikyk@gmail.com C on gr es s Pr ogr am s & Ev en t s

* This program is subject to change without notice.

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6th Congress, Beijing, China

May 5-7, 2012

Proteomics-Its Principles and Applications Education & Training Workshop

Time: 10:00-16:15, May 5, 2012 Venue: Room 301AB, China National Convention Center Chairs: Kazuyuki Nakamura, Richard Simpson

Schedule:
10:00-10:15 10:15-10:30 10:30-11:05 11:05-11:40 11:40-12:15 12:15-13:15 12:15 12:35 12:55 13:15-14:15 13:15 13:35 13:55 14:15-14:50 14:50-15:05 15:05-15:40 15:40-16:15 Introduction to IPTP Kazuyuki Nakamura, Yamaguchi University, Japan E&T in India Ravi Sirdesmukh, Institute of Bioinformatics, ITPL, India Genome and Proteome Siqi Liu, Beijing Institute of Genomics, CAS, China Stem Cell Proteome Yu-Ju Chen, Institute of Chemistry, Academia Sinica, Chinese Taipei Secretome Richard Simpson, La Trobe University, Australia Luncheon Seminar Software Solutions for Mining Glycoslate Proteomics Datasets David Horn, ThermoFisher Accelerating Biomarker and Proteomics Research with TripleTOF 5600 System Wenhai Jin, AB SCIEX Introducing Technologies Facilitate Biomarker Discovery and Beyond Liu Ning, Bio-Rad Presentation by Young Scientist Travel Award Winners Novel Strategy for Drug Target Discovery by Chemical Proteomics Approach Lianghai Hu, Jilin University, China HollowFiber Culture System: An Alternative in Sample Preparation in Secretome Studies Qifeng Lin, National University of Singapore, Singapore Membrane Proteomics: Opportunity for Mining Cancer Biomarkers Chia-Li Han, Institute of Chemistry, Academia Sinica, Chinese Taipei Cancer Proteome Tadashi Kondo, National Cancer Center Research Institute, Japan Coffee Break Plasma Proteome Mark Baker, Macquarie University, Australia Disease Proteomics Terence Poon, The Chinese University of Hong Kong, Hong Kong SAR, China Co ng r es s P r og r a m s & E ve n t s

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10 th Anniversary for CNHUPO & Release of Special Book Liver Proteome

Time: 18:20-18:50, May 5, 2012 Venue: Plenary Hall A, China National Convention Center Moderator: Jun Qin

Schedule:
1. CNHUPO in a Decade Fuchu He, Honorary President of CNHUPO, Pioneer of CNHUPO 2. Awards for the CNHUPO 10th Anniversary Xiaohong Qian, Vice President of CNHUPO Distinguished Achievement Award: Fuchu He Distinguished Mentoring Award: Zihe Rao Technology Innovation Award: Yukui Zhang Distinguished Service Award: Pengyuan Yang 3. Introduction of Liver Proteome A Special Edition Pengyuan Yang, President of CNHUPO 4. Ceremony for the Publication of Liver ProteomeA Special Edition

Co ng r es s P r og r a m s & E ve n t s

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