APPLICATION OF IT IN HEALTHCARE

Molecular biology-study of
molecules.. Eg.DNA ,RNA,PROTEINS..etc. +

information technology =

BIOINFORMATICS

 PROTEIN

 WHY

A NEED TO STUDY MOLECULES AND THEIR STRUCTURES.?

change in a small part of a structure of a molecule can result in a disease. Eg. Sickel cell anemia.
To

tackle the effects of an unwanted micro-organism. Eg. H1N1.

 H1N1

VIRUS

DATABASES-collection of
structured information.

TYPES OF DATABASES1.PRIMARY SEQUENCES

2.SECONDARY SEQUENCES 3.ORGANISM SPECIFIC 4.MISCELLANOUS

1.PRIMARY SEQUENCES DATABASE Stores SEQUENCE DATA of nucleic acid ,amino acid and protiens (nucleic acid amino acid proteins)

Maintained by NCBI-national centre for biotechnology information..(GENBANK)

EMBL-european molbio lab..(nucleotide sequence) SWISS-PROT-protein sequence.

 SECONDARY

DATABASE-

SEQUENCE

Raw

data is derived from primary database. information on sequence patterns and motifs.

Contains

Motifs and patterns.

 ORGANISM
Contains

SPECIFIC-

genomic databases of microorganisms. N number of genes together make a genome..(pool of genes)

Eg.

E.coli,plants,mouse and even humans.

 MISCELLANOUS
Specialised Eg.

DATABASE-

sequences databases

rRNA,tRNA,

OMIM-(online

mendelian inheritance in man) for human genetics. study of genes.

GENETICS-

 APPLICATIONS

1.In genomics-complete DNA

sequences are stored. 2.

In proteomics-study protein
expression in an organism.

3.chemoinformatics-storage of chemical structures.

4.pharmainformaticspharmaceutical industries.

 Drug designing-how the drug interacts with the target.

Structure

of the drug.

CLINICAL

MEDICINES

Basic applications

Improve health care quality; Prevent medical errors; Reduce health care costs; Increase administrative efficiencies

Decrease paperwork; and

Expand access to affordable care.

 Early

detection of infectious disease outbreaks around the country;

Improved

tracking of chronic disease management; and

Maintain patient records in hospitals and clinics.

Monitor patients' vital signs in hospital rooms and at home Computer-assisted medical tests. Research and diagnose medical conditions.

 Implant

computerized devices (e.g., pacemakers) that allow patients to live longer computer-controlled devices during operations that require great precision (e.g., laser eye surgery and heart surgery) of computer-aided surgery for training prior to performing surgery on live humans.

Use

Use

Maintain patient records in hospitals and clinics. Monitor patients' vital signs in hospital rooms and at home Computer-assisted medical tests

Research and diagnose medical conditions

 Implant

computerized devices (e.g., pacemakers) that allow patients to live longer

Use

computer-controlled Devices during operations that require great precision (e.g.,laser eye surgery and heart surgery)

Telemedicine through computers with videoconferencing capabilities.

Use of computer-aided surgery for training prior to performing surgery on live humans.