Universidad Cooperativa de Colombia- Seccional Magdalena Facultad de Ciencias de la Salud -Programa Cincias Bsicas Mdicas Programa Medicina- rea

Patologa, III Semestre-Aprendizaje Basado en Problema (ABP)

Caso 1-Hipertrofia del Miocardio Caso 2-Hiperplasia Nodular de la Prstata

Caso 3-Metaplasia Escamosa , Pelvis Renal

Caso 4.-Metamorfosis Grasa Heptica Caso 5. Atrofia de testculo

Caso 1. Hipertrofia Cardiaca

Caso 2. Hiperplasia de Prostata

This kidney was removed from another autopsy patient who had prostatic hyperplasia resulting in marked urinary retention and back-flow of urine from the bladder into the ureters and renal pelvis. The increased pressure inside the renal pelvis resulted in dilation of the renal pelvis (1) and pressure atrophy of the cortex (2). This change in the kidney is called hydronephrosis.

Caso 3. Metaplasia Escamosa.No Pelvis Renal

This is a low-power photomicrograph showing the full cortical and medullary thickness of the kidney. Note that there is a dilated calyx containing some red blood cells in the center of the section (arrow). The cortex is markedly thin and has severe lesions of degeneration and atrophy, although these are hard to appreciate at this low magnification.

Caso 4. Higado Graso

This gross photograph of liver tissue illustrates the yellowish color of the liver parenchyma. The yellow color indicates high fat content in this tissue. Compare this with the normal dark red color of liver.

This higher-power photomicrograph of the centrilobular area gives the appearance of fatty tissue, as indicated by many empty spaces. Very few normal liver cells can be seen in this slide. A few more normal-appearing hepatocytes are present at the left portion of the slide (arrows).

An oil red O stain for fat was performed on a frozen section of this liver tissue. The red droplets represent fat in the tissue which is typical of fatty degeneration in the liver. By using frozen sections the tissues do not have to be dehydrated through alcohol solutions and thus the fat does not get washed out.

This photomicrograph of the liver is from another patient with a history of alcohol use. There are some clear vacuoles indicating fat droplets (1) and there are numerous red-staining granular deposits within the cytoplasm of hepatocytes (2)--this is alcoholic hyalin. Alcoholic hyalin is easily distinguished from red blood cells (3) that are also present in this section.

This is a low-power photomicrograph of liver stained with a trichrome stain. In this section, connective tissue stains green (arrows) and hepatic parenchymal cells are red. Note that many of the parenchymal cells have clear spaces indicating fatty degeneration. The proliferation of scar tissue between the liver lobules is the result of cirrhosis.

This gross photograph of liver demonstrates severe nodular cirrhosis. Note the extensive scarring of the capsule and the nodular projections of tissue through the uncut capsule in this tissue. The green color is due to the accumulation of bile pigment.

This is a cut surface of the same tissue seen in the previous slide. Note the marked nodular pattern. The paler-staining areas between the round nodules represent fibrous connective tissue.

Caso 5. Atrofia Testicular