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of active and passive immunity and vaccination with live and inactivated vaccines. Contact us by Email at <nipinfo@cdc.gov> if you wish to obtain a copy of this tape.
Principles of Vaccination
Epidemiology and Prevention of VaccinePreventable Diseases
Principles of Vaccination
Self vs. nonself Protection from infectious disease Usually indicated by the presence
of antibody
Immunity
Principles of Vaccination
Active Immunity
Passive Immunity
A2
Principles of Vaccination
Antigen
Protein molecules
(immunoglobulin) produced by B lymphocytes to help eliminate an antigen
Antibody
Passive Immunity
Temporary protection
Homologous human
hyperimmune globulin
Heterologous hyperimmune
serum (antitoxin)
Monoclonal Antibody
Palivizumab (Synagis)
Monoclonal Contains only RSV antibody
Vaccination
Classification of Vaccines
Inactivated
Inactivated Vaccines
Whole
Fractional
Principles of Vaccination
General Rule
The more similar a vaccine is to the natural disease, the better the immune response to the vaccine.
Unstable
Viral
measles, mumps, rubella, vaccinia, varicella, yellow fever, influenza, (oral polio) (rotavirus) BCG, oral typhoid
Bacterial
Inactivated Vaccines
Inactivated Vaccines
Whole cell vaccines
Viral
Bacterial
Inactivated Vaccines
Fractional vaccines
Subunit
Toxoid
Polysaccharide Vaccines
Pure polysaccharide
Conjugate polysaccharide
Immunogenicity improved by
conjugation
Hotline Email
800.232.2522 nipinfo@cdc.gov
Website
www.cdc.gov/nip