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Psychology 242 Introduction to Research

Quasi-experimental designs
Quasi-experiments

Experimental designs for studies in nature.

Studying naturally occurring events

Measurement studies
Retrospective designs Evaluate existing groups or program

Single shot survey or measure


Non-equivalent groups Time series designs
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True v. quasi-experimental designs

True experiments:
Emphasize internal validity Assess cause & effect (in
relatively artificial environment)

Quasi-experiments:
Emphasize external validity Describe real / naturally occurring events Clear to exploratory hypotheses

Test clear, a priori hypotheses

Participants assigned to Existing or non-equivalent experimental v. control groups groups Random or matching Non-random assignment Participants & experimenter Participants not blind Blind to assignment Control group not possible?

Control study procedures Control often not possible Create / manipulate independent May not be able to manipulate variable the independent variable Control procedures & measures Partial control of procedures & measures
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Psychology 242 Introduction to Research

Quasi-experiments: naturally occurring events

Studying naturally occurring events

Measurement studies Retrospective designs


Evaluate existing groups or program Single shot survey or measure Non-equivalent groups

Time series designs

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Measurement studies

1. Naturally occurring events; examples


Event
(Predictor)

Study question
(Outcome)
Stress -> immune system Stress & coping

Natural disaster / stressor


3-mile island S.F. earthquake

Crime / trauma
Iraq service, 9 / 11 / 01 PTSD & treatment Contrails & climate change Voting patterns Health behavior
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Historical event
9/11 & air travel ban Economic collapse

Publicity / cultural event


Info. re: Hormone replacement
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Naturally occurring events, 2

Independent variable:

Predictor variable (e.g., natural disaster) often assessed after the event (post-hoc). Researcher has little control over dose / type of predictor

Participant selection

No control over who is exposure to event Some control over selection of sample (e.g., via targeted
sampling)

Many potential confounding variables Outcome (dependent) variables:


No control with archival data Some control with surveys Use retrospective (measured) variables to clarify interpretation of outcomes or test hypothesis.
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Naturally occurring events: Retrospective designs

Using retrospective (measured) variables to clarify interpretation of outcomes or test hypothesis.


Retrospective variable(s)
Social support Psych. history
[archive? Self-report?]

Event
(Predictor variable) earthquake [v. control city?] crime / trauma
[v. control people?]

Outcome variable
stress & coping mental health voting patterns

Personal attitudes

historical event

Demographics

cultural event

health behavior

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Psychology 242 Introduction to Research

Quasi-experiments: Existing groups

Studying naturally occurring events Measurement studies Retrospective designs

Evaluate existing groups or program

Single shot survey or measure


Non-equivalent groups
Time series designs
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Existing groups

Existing groups:
Single self-selected group; no comparison possible
users of psychotherapy (or any product) members of group or cult [contrast with demographically
matched controls?]

Two or more groups, with self-selection and / or "non-blind" assignment


Psychological interventions: therapy v. wait list, etc.

Two or more groups, no random assignment


Comparing schools / cities / existing groups
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Psychology 242 Introduction to Research

One shot case studies


Naturally occurring event or social change Observe1

Group

May control selection of study group, or must use Convenience sample. Other data may be available about group.

Typically no control over event. Not a true Independent Variable

Dependent Variable(s): May or may not have control over measures (e.g., surveys v. archival measures).

Typical use: Surveys or measures after an event. Heuristic value: generating hypotheses for later study

or confirm controlled data in real world setting.


No control over selection of people into the event.

Internal / External validity:


Potentially no control over selection into measurement

group.
No control group; uncontrollable event, or other groups

may not need the intervention (e.g., therapy)


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Example of one-shot case study

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Example: Consumer Reports psychotherapy survey


[Click for paper]

Research questions: Does psychotherapy work from consumer view? Who gets therapy / what does it consist of? Do consumer responses vary by type of therapy? Research approach: One shot case study / survey Sampling frame: Any therapy or psychological service user No real information re: population of therapy users. Sampling procedure: 4,100 Consumer reports readers responding to in magazine mail-back survey form
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One shot: Consumer reports survey, 2

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Experimental Controls

Evaluate by gender, type of treatment, medications, to provide more differentiated analysis

Negatives:
Selection bias no control over who got therapy (self-selection) of those who got therapy, no control over who

returned a survey (secondary self-selection) Cursory outcome measures: satisfaction rather than mental health

Positives:
Huge, national sample Wholly anonymous, 3rd party data collection; less bias Real world assessment of product quality
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One shot: Consumer reports survey, 3

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Key distinction in psychological interventions: efficacy v. effectiveness research

Efficacy; true experimental design / Lab-basis


Rigorous controls; High internal validity

Test basic theory or highly specific technique

Do the specific ingredients (or theory) of this treatment validly induce the key outcome?

Effectiveness; quasi-experimental; natural or


applied setting
Less or no control; naturally occurring treatment High external validity

Does treatment work in real patients w/real therapists?


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Comparisons of study types:

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(Consumer reports 4)

Efficacy experiment v.
One specific diagnosis Rigorous control group no treatment condition attention control Random assignment Manualized / uniform treatments High Fidelity to treatment method Fixed number of sessions. Well operationalized outcomes, e.g., clinician-diagnosed disorder Standard / validated self-report symptom scales

Effectiveness research
Multiple diagnoses & severities No control group, 2nd controls Archival, via pt. characteristics Self-selection; shopping Multiple / mixed treatments Highly tailored to patient # sessions is patient based. Diverse, self-referenced outcomes Subjective sense of wellness Lessening of problem behaviors or moods Personal assessment of functioning Self-rated: cannot be "blind" Diverse times since treatment Retrospective rather than prospective
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Blind" raters or diagnosticians


("single-blind: patient & therapist know what the treatment is..)

Patients followed for a fixed period


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Consumer reports survey, 5.

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Survey findings on therapy effectiveness:


People who got more treatment (> 6 months) did better. For patients presenting For general health MH

problem(s) all specialists did about the same.

specialists did best, marriage counselors worst.

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Consumer reports survey, 6.

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Other effectiveness / descriptive findings:


3/4

went to mental-health specialist.

Patients who rated themselves worse at

outset made the most progress.


AA very highly evaluated Therapy did as well as medications

40% got drugs;

MDs gave medications to 83% of patients MH pros; 20% drug treatments 50% who got drugs got no counseling 20% got no information about side effects 40% of anti-anxiety drugs given > 1 year
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More complex case studies


Naturally occurring event Observation + Archival Controls

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Group

Basic selection / convenience biases, uncontrollable event.

Dependent Variable(s): Combine survey or other measures with archival or ancillary data as Control variables.

Example 1: San Francisco earthquake & coping

Sampling frame: - Randomly selected survey participants


Outcomes: - Standardized mental health scales - Self-reports of stress

Quasi-controls: - population norms on outcomes - ancillary measures, e.g., social support


Findings:
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- High rates of stress Rx, - Social support buffers stress


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One Shot + archival control: examples

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Example 2: Stress and immune functioning


Event: - Three-mile Island nuclear accident

Sampling frame: - Randomly selected residents of geographic area around TMI Outcomes: - Blood draws for immune markers - Self-reports of stress

Quasi-controls: - Demographically matched sample - Archival data on health & illness

Findings:

- Long-term suppression of key immune markers (natural killer cells, T cells)


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One shot designs with archival controls, 3

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Example 3: Psych. & Health effects of bereavement


Event: - Loss of spouse

Sampling frame: - Hospital records, self-selected spouses


Outcomes: - Blood draws for immune markers - Standardized mental health scales - Occupational functioning - Population norms on MH scales - Archival data: occupation & illness

Quasi-controls:

Findings:

- Long-term immune suppression - Social support buffered stress - impact of bereavement > other stressors
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One shot designs; Summary One Shot designs: no control over independent variable(s), only partial control over measurement:

Psychology 242 Introduction to Research

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An experiment is not possible

There cannot be a control group Pre- measures not possible or practical

Virtue:

Assess naturally occurring or uncontrollable socially or politically important events Provides real world look at processes that are typically studied in experiments: Effectiveness v. Efficacy data Archival data can help interpret the findings / control some alternate interpretations.

Liability:

lack of control group creates multiple threats to internal validity No pre-measure makes interpretation (e.g., of change) difficult.
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Psychology 242 Introduction to Research

Quasi-experiments: Existing groups

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Studying naturally occurring events Measurement studies Retrospective designs

Evaluate existing groups or program Single shot survey or measure

Non-equivalent groups
Time series designs
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One group pre-test post-test


Observe1 Intervention or event Observe2 Outcome Assessment Typically controllable, but may be archival. Baseline Assessment May or may not have control over measures (e.g., surveys v. archival measures).

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Group Selected or convenience sample.

Event or intervention May or may not be controllable by researcher, e.g., policy change.

Uses: Educational & social environments


Political or health policy change
Not feasible to have a control group System-wide intervention / social change (school, public health campaign..)
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Key design feature: no control group.


Group Observe1 Observe1 Intervention or event Observe2 Observe2

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Confound

Threats to internal validity (confounds):


History
Maturation Reactive measures Statistical regression Mortality /
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Historical / cultural events occur between baseline & follow-up.


Individual maturation or growth occurs between baseline & follow-up. People respond to being measured or being a measured a second time. Extreme scores at baseline regress to a more moderate level over time.

People leave the experiment nondrop-out randomly (i.e., for reasons that may affect the results). Week 12-13, quasi-experimental designs. Back Next
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Psychology 242 Introduction to Research

Examples: One group pre- post-, HIV testing

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Example 1: Effects of HIV testing on sexual risk.


Event: - Receipt of HIV testing & counseling

Sampling frame: - Participants in testing centers Study structure: - Baseline retrospective interview at testing session - Follow-up interview 3 months later Quasi-controls: Outcomes:
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- Population characteristics to predict between-group differences - Self-reports of sexual risk


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Example: One group pre- post-, HIV, 2

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Effects of HIV testing on sexual risk, cont.

Findings:

- Significant shifts toward safety - Few demographic predictors of risk or risk change

Threats - Self-selection into testing group to internal - Mortality: non-random drop-out(?) validity - History: general shift in norms & behavior during study time may account for observed change - Instrument change; people may answer more conservatively during a follow-up interview
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Examples: One group pre- post- , Education

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Example 2: Educational reform & No Child left behind testing requirements.


Intervention: - Standardized testing becomes integral to educational programs & school evaluation.

Sampling frame & - Longitudinal data across multiple Study structure: years in target school grades. - No control group possible.

Quasi-controls:

- Population characteristics to predict between-group differences


- Standardized test scores
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Outcomes:
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Example: One group pre- post-, education, 2

Education reform & test scores.

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Findings:

Modest, statistically significant increase in scores Usual demographic predictors of change; more affluent, better schools..

Internal validity?:

Reactive measures; teachers & students do better when measured; (they also cheat; see Houston Miracle article)
Instrumentation: kids get better at taking standardized tests, teacher better at teaching them History: General cultural shift

Education more prominent in city More affluent families sending kids to public schools
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One group pre- post- designs; Summary


An experiment is not possible There cannot be a control group Researchers have control over measurement and the independent variable

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One group pre- post- test design useful where:


Virtues:

provide data on naturally occurring socially or politically important events Pre-measure allows researcher to interpret change & examine status of groups at baseline. History maturation statistical regression reactive measures mortality / drop-out
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Liability: lack of control


group creates multiple threats to internal validity:

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Non-equivalent two-group designs


Intervention or event

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#1; Static Group Design


Group1 Group2 Observe1 Observe1

(No baseline)

Contrast group

Groups are not equivalent at baseline, due to.. Self-selection Non-random assignment Use of existing groups Participants not blind

Assessments may or may not be controlled Survey or interviews Archival / existing data, e.g., clinic records, grades Intervention or event may or may not be controlled by researcher; Existing program Experimental intervention Naturally occurring event (..9/11..)
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Non-equivalent designs; pre- post-

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#2 Two Group Pre- Post- Design


Group Group Observe1 Observe1 Intervention or event Contrast group Observe2 Observe2

Non-equivalent groups Self-selection Non-random assignment Use of existing groups Participants not blind

Intervention & Assessments often controlled by researcher in these designs.

Observation1 used to
Assess equivalence of groups at baseline Test for threats to internal validity:
Reactive measures History, mortality effects Regression effects
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Similar to true experimental design, except for non-equivalent groups

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Examples: Non-equivalent groups, condoms

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Example Non-equivalent control group design: Effects of condom distribution on sexual safety
Intervention: - Condom education & distribution in High School health classes

Sampling frame: - Schools in New York & Chicago - Schools matched for SES, race, size Study structure: - NY = intervention schools, Chicago are contrast schools. - Baseline, sexual health programming, end of year Follow-up Outcomes:
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- Clinical measures: STDs - Self-reports: sexual activity & safety


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Examples: Non-equivalent groups, condoms, 2

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Condom distribution, cont.

Findings:

NY (intervention) students; lower STD rate, safer sex NY and Chicago students; similar levels of sexual activity Thus; sexual health classes appeared to increase safety without increasing sexual activity. Reactive measures; Study is not blind; NY students know they are the intervention group

Internal validity?:

Non-equivalent groups: Possible differences between cities = unmeasured confounds


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Non-equivalent designs

Soloman 4-group design


Observe2 Observe2

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Group 1

Observe1 Observe1

Intervention Contrast group

Group 2
Group 3 Group 4

Intervention
Contrast group

Observe2
Observe2

Groups 1 & 2:
Observation1 used to Assess equivalence of groups at baseline Test threats to internal validity

Groups 3 & 4:

Post-test only tests for reactive effects of assessment Compare 1+2 versus 3+4 Test interaction of treatment group x pre- post- versus post- only
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Non-equivalent 2 group designs: Summary

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Most common quasi-experimental approach. Used where:


Some form of control or contrast group is possible Groups cannot be equivalent:


Participants cannot be blind re: group assignment Random assignment not possible Must use existing or self-selected groups.

Virtue: Study natural / real world interventions Contrast group lessens major threats to internal validity Liability: non-equivalent groups = possible confound.

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Quasi-experiments: Existing groups

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Studying naturally occurring events Measurement studies Retrospective designs

Evaluate existing groups or program Single shot survey or measure

Non-equivalent groups

Time series designs


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Interrupted time series design


Measure1 M2 M3 M4 M5 M6 Intervention or event

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Group

Test effect of intervention or event on ongoing series of measurements. Intervention may be experimental or observed
Policy shift, e.g., educational policy
Uncontrolled event; e.g., 9/11/01, Media event

Assessments may be experimental or archival


Successive cross-sectional surveys Traffic data, clinic or crime reports, test scores
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Time series designs

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Group

Measure1

M2

M3

M4

M5

M6

Multiple baseline

Intervention or event

Demonstrate highly stable effect long-term crime rates disease prevalence economic performance
Show steady rate of change

Hypothesis; tested by:

Shift in stable rate after intervention Increase / decrease in rate of change after intervention

Threats to internal validity:


sensitive to very local history Single group possibly prey to confound

Advantage for internal validity


Eliminates carryover effects of repeated measurement tests maturation, history, reactive measurement, etc

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Example of interrupted time series:

Shift in Baboon culture.

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Core question: Do baboon troops develop and transmit a learned culture? Baseline: Long-term observational data on aggressiveness in a specific baboon troop. Intervention: Tuberculosis outbreak due to infected food. Dominant / aggressive males fed first
are selectively infected are naturally culled from troop Naturally occurring event in >20yr. ongoing
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field study.

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Baboon culture: findings

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Quasi-controls: Parallel data from other baboon troops.


Outcome measures: Standardized indices of aggression & dominance behavior Core finding: With dominant males gone,
remaining males showed more cooperative behavior Enhanced cooperation was transmitted across generation, showing learned culture.
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Example: Interrupted time series data

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The Magic Johnson effect on HIV testing


Data: Archival records of HIV tests reported to CDC,
collected monthly

Data show stable baseline over multiple observations Timing of intervention precise relative to data collection
Uncontrollable, naturally occurring event Tests hypothesis re: modeling effects in health behavior

Intervention: Magic reports infection on national TV.


Finding: Initial spike in testing rates, followed by


leveling off at higher base rate.

Initial increase expected Hypothesis tested by longer-term shift in base rate, available due to archival time-series data Effect found for both genders.
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Example of time-series data: Magic / HIV effect.

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Time-series data showing shift in HIV testing after Magics announcement.

Magics Announcement

Initial spike New, higher base rate Low & variable baserate of testing

Multiple (monthly) measures.

Tesoriero, J.M., Sorin, M.D., Burrows, K.A., LaChance-McCullough, M.L. (1995). Harnessing the heightened public awareness of celebrity HIV disclosures: Magic and Cookie Johnson and HIV testing. AIDS Education and Prevention, 232-250.
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Multiple time series study

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Multiple time series data


Group 1 Group 2 Measure1 Measure1 M2 M2 M3 M3 M4 M4 M5 M5 M6 M6

Groups typically formed by


blocking variable measured post-hoc; Health claims in NYC v. other cities post- 9/11/01 Younger v. older voting patterns post- Iraq invasion Heterosexual v. gay HIV testing rates post- Magic Johnson media event.
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Intervention or event

Hypothesis; tested by
interaction of blocking variable by repeated measure:

Is shift in stable rate ( rate of change) greater in one group than another?

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Blocking variables

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Testing blocking variables in the HIV testing time-series data. Core questions:

Both heterosexuals and Ethnic minorities had low HIV testing rates

May feel HIV is not relevant to them it is a white gay problem. They may lack resources or venues for testing.

Will having a prominent African-American Heterosexual disclose HIV+ status may change those perceptions? Heterosexuals will respond more strongly to the Magic Johnson media event than will gay/bisexual men.
African-American and Latino men and women will respond most strongly.
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Hypotheses:

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Blocking variables: sexual orientation, 1.

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Testing blocking variables: Gay / IDU data.


High base-line and high variability in testing rates among men with risky partners, and IDUs. Gay / bisexual men show less variable, but generally lower baserates. Risky men & IDUs slightly increase, with substantial variability.

Gay & bisexual men show no change.

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Blocking variables: sexual orientation, 2.

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Testing blocking variables: Heterosexuals.


In contrast to gay / bisexual men or IDUs, heterosexual show an initially low baserate. Followed by a large spike after the announcement

And a much higher new baserate.

The hypothesis that heterosexuals would be more affected by the Magic announcement was supported by the interaction of Time x the blocking variable of sexual orientation.
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Blocking variables: ethnic differences

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Testing blocking variables: Ethnic differences.


African-Americans and Hispanics show low baserates and a high spike postannouncement

Both groups go back toward their baselines shortly post-announcement.

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Blocking variables: ethnic differences, 2.

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Ethnic differences: White participants.

HIV testing among Whites was similar to African-Americans & Hispanics at baseline, They showed stable, much higher testing rate after Magics HIV announcement.

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Summary: Blocking variables in time series data

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A series of measures before & after an event allows us to clearly identify patterns of behavior, and to test group differences (via blocking variables). The hypothesis that ethnic groups would differ was supported by interaction of Time x the blocking variable of ethnicity (but in a direction that was not predicted: Whites showed more change).
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Time series designs: Summary

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Time series is most common with archival data: existing, standard records collected for other purposes. Used where: The hypothesis concerns changes in long-term trends Typically an experiment cannot be run
Simple practicality or cost, e.g., health care issues Ethics; crime rates, rates of domestic violence, etc. The target events are not controllable.

Virtue:

Study natural / real world processes or interventions Blocking variables comparing time trends across groups -- lessens major threats to internal validity
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Liability: lack of control = possible confound.


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Psychology 242 Introduction to Research

Quick quiz

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Researchers often use _____ to help interpret single shot surveys


A = paradigm change B = measurement studies C = experimental controls D = retrospective measures

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Quick quiz, 2

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Match:

A = Mortality / drop-out

Historical / cultural events occur between baseline & follow-up.


Individual maturation or growth occurs between baseline & follow-up. People respond to being measured or being a measured a second time. Extreme scores at baseline regress to a more moderate level over time.

B = Maturation
C = History D = Statistical regression E = Reactive measures
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People leave the experiment nonrandomly (i.e., for reasons that may affect the results). Week 12-13, quasi-experimental designs. Back Next
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Quick quiz, 2

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Match:
A = Mortality / drop-out B = Maturation C = History
People respond to being measured or being a measured a second time.

D = Statistical regression E = Reactive measures


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Quick quiz, 3

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Match:

A = Mortality / drop-out

B = Maturation
C = History D = Statistical regression E = Reactive measures
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Growth or natural change between baseline & follow-up.

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Quick quiz, 4

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Match:

A = Mortality / drop-out

B = Maturation
C = History D = Statistical regression E = Reactive measures
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People leave the experiment nonrandomly (i.e., for reasons that may affect the results).

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Quick quiz 5

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Group

Measure1

M2

M3

M4

M5

M6

This is called a:

Intervention or event

A = Threat to internal validity


B = Manipulation check C = Multiple baseline

D = ..lot of work.

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Quasi-experiments; Summary

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1. Study naturally occurring events that could not be brought into a lab or a true experiment.

Measurement studies
Retrospective designs

2. Evaluate existing groups or program(s)

Single shot survey or measure of an intervention

With or without control variables

Non-equivalent / pre-existing groups

Static group or 2 group pre- post- design

Time series designs, often with archival data

Trade off internal for external validity


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Exam issues

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Key exam issues:


Slide 2: true v. quasi experiments Threats to internal validity Basic forms of quasi-experiments

Single shot Single group pre- post- test Non-equivalent two group designs:

Self-selection (in or out [mortality]) Existing groups Non-blind Non- random assignment

Interrupted time-series / group contrasts

Virtues (external validity) and problems (internal validity)


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