Professional Documents
Culture Documents
Function, and Autism
Autism One Conference
Chicago, IL
May 23, 2009
Education and research
• Inflammation
• Malabsorption
• Developmental delay
• Food allergies and other immune system problems
Some foods not tolerated in autism
• Nutritional Insufficiency?
• Family lifestyles
• Cost and availability
Observed effects of enzymes
Bovine
Casein
x-x-x-x-x-x-x- -tyr-pro-phe-pro-glu- x-x-x-x-x-x-x-
x pro-ile- x
Casomorphin
Example: DPP IV peptidase
tyr-pro-phe-pro-glu-pro-ile
DPP IV
Casein amino acid sequence affected by DPP IV
Bovine
Casein
x-x-x-x- tyr- phe- glu- il-x-x-x-x
pro- pro- pro- e
(1)
Pepsin
DPP IV
In Stomach
No casomorphin formed!
Blocked peptide formation by multiple proteases
Bovine
Casein
x-x-x-x-tyr-pro- pro- pro- -x-x-x-x
phe- glu- ile
Protease 4.5 Protease 6.0
devin.houston@houstonenzymes.com
www.houstonenzymes.com
18667578627