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Introduction to Bone tissue, its composition Functions of skeletal system Classification of bone by:
o Shape, o Region, o Development, o Structure
Bone tissue
In simplified terms, bone itself is composed of: Cells Osteoblasts (bone making cells) Osteocytes (Mature bone cells, , maintain bone matrix) Osteoclasts (bone destroying cells) Collagen fibers that contribute to hardness of the bone Matrix (cement) mostly calcium phosphate, calcium carbonate & other salts that give bone its strength & structure Together, collagen & matrix act as reinforcement Bone is constantly turning over (old bone replaced by new bone) Bone density changes as with age Weight bearing activity increases bone density (stimulates osteoblasts) Two types of bone tissue: spongy
compact
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Bone tissue
Spongy bone forms flat and short bones as well as ends (epiphyses) of long bones Compact bone solid, dense bone compact bone forms external shell
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Types of Bones..contd
CLASSIFICATION OF BONES
Short Bones- cube like bones, provide stability and strength. Example: -Trapezoid-finger -Carpal & tarsal bones Irregular bones- Various functions including protection, stability and strength. Example: -Vertebrae -Pelvis or hip bone
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CLASSIFICATION OF BONES
Pneumatic Bones- Certain irregular bones contain large air spaces lined by epithelium. Examples: -Maxilla, Sphenoid,Ethmoid etc They make the skull light in weight, help in resonance of voice, and act as air conditioning chambers for the inspired air. Sesamoid Bones- These are the bony nodules found embedded in the tendons or joint capsules. They have no periosteum & ossify after birth. Example: -Patella, Pisiform etc Accessory (supernumerary) Bones:These are not always present. They may occur as ununited epiphyses developed from extra centres of ossification., e.g sutural bones etc. These are often bilateral and have smooth surfaces without any callus.
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Medullary Cavity Nutrient Art & Vein Epiphyseal Plates Epiphyseal Art & Vein Outer: Dense irregular CT Inner: Osteoblasts, osteoclasts Does not cover epiphyses Attaches to bone matrix via collagen fibers Osteoblasts, osteoclasts Covers trabeculae, lines medullary cavity
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2 Epiphyses
Periosteum
Endosteum
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Vertebral column
Spine built of 26 vertebrae Five vertebral regions cervical vertebrae (7) in the neck thoracic vertebrae (12) in the thorax lumbar vertebrae (5) in the low back region sacrum (5, fused) coccyx (4, fused)
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Thorax
Sternum (breast bone) =1 Ribs 1-7 are true ribs (join sternum directly) 8-12 are false ribs (do not join sternum directly but via 7th rib) 11-12 are floating (not bound anteriorly)
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Scapula
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Upper extremity
Bones Humerus ulna & radius
carpal bones
metacarpal bones phalanges
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Lower extremity
Bones femur and patella tibia & fibula tarsal bones metatarsals
phalanges
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Pelvic girdle
Bones of Pelvis Coxal (Hip) bones (2) Sacrum Coccyx
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Hip bones
3 parts Ilium Ischium Pubis 3 separate parts in childhood Fused into single bone in adults
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1) Intramembranous Ossification
Membrane bones: most skull bones and clavicle Osteoblasts in membrane secrete osteoid that mineralizes Osteocytes maintain new bone tissue Trabeculae forms between blood vessels Grows into thickened plates at periphery = compact bone Periosteum forms over it
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CLASSIFICATION OF BONES (3-Developmental) 2) Endochondral Ossification: All other bones Begins with a cartilaginous model Perichondrium becomes replaced by periosteum Cartilage in diaphysis calcifies Trabeculae forms from Periosteal bud Periosteal bud = arteries & veins, cells forming bone marrow, osteoblasts, osteoclasts Medullary cavity is formed by action of osteoclasts Epiphyses grow and eventually calcify Epiphyseal plates remain cartilage for up to 20 years Bone & Cartilages By:CK (FIHS) 28 2/1/2014
3) Membrano-cartilaginous bones:
Ossify partly in membrane and partly in cartilage. Example:- Clavicle, Mandible, Occipital, Temporal, sphenoid etc.
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A-Macroscopically the architecture of bone may be ; 1- Compact Bone 2- Cancellous spongy/trabecular bone 1-Compact Bone:- Compact bone is dense in texture like ivory, but is extremely porous. - It is best developed in the cortex of the long bones. - These have adaptation of bending and twisting by force.
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2- Cancellous Spongy, or Trabecular Bone:- It is open in texture and is made up of a meshwork of trabeculae (rods & plates). - This meshwork is of 3 types; 1- Meshwork of rods 2- Meshwork of plates 3- Meshwork of rods & plates - Cancellous bone is an adaptation to compressive forces.
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B. Microscopically, the bone is of 4 types; 1. Lamellar bone:-Most of mature human bones (compact/spongy) -These are composed of thin plates of bony tissue called lamellae. -These are arranged in piles in a cancellous bone, but in concentric cylinders (Haversian system or secondary osteon) in compact bone. 2. Fibrous bone:- -in young fetus, common in reptiles & amphibian 3&4. Dentine & Cement in teeth.
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Cartilages
One of the most remarkable tissues of the human body. Its inert and lifeless, bones are living, dynamic structures. Weaker than bone More flexible than bone Cells in an abundant matrix. Cell Types Chondroblasts Chondrocytes in lacunae
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Skeletal Cartilages
Initially our skeleton is made up of cartilages and fibrous membranes. Gradually our skeletal cartilages are replaced by bone. Upon reaching adulthood the skeleton becomes almost fully ossified. Only a few cartilages remain in the adult skeleton.
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Cartilages
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1.Hyaline cartilages
Greek Hyalos= transparent stone Its bluish white and translucent in color The most prevalent type of cartilage Its high proportion of collagen fibers give it flexibility and resilience while providing support Upon examination the tissue appears white, frosted, and smooth.
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2.Elastic cartilage
Elastic cartilage is similar to hyaline cartilage but with more elastic fibers Its elastic fibers enable it to withstand repeated bending Found only in the external ear and the epiglottis
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3.Fibrocartilage
The tissue contains parallel rows chondrocytes alternating with collagen fibers. Tissue is highly compressible and has great tensile strength. Found in thick pad-like structures like the menisci of the knee or the discs of the vertebral column.
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Growth of cartilage
Cartilage grows in two ways Appositional growth occurs when cells in the surrounding perichondrium secrete new matrix next to existing cartilage tissue (growth from the outside). Interstitial growth occurs when the chondrocytes within the cartilage divide and secrete new matrix, expanding the cartilage (growth from within).
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Think you
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