Professional Documents
Culture Documents
Immune deficiencies
Primary Deficiency results from improper
development of immune congenital or
inherited
Secondary Deficiency results from some
interference with an already developed
Central and Peripheral Lymphoid Organs
Immune Function
• Natural immunity: nonspecific response to any foreign
invader
White blood cell action: release cell mediators such as
histamine, bradykinin, and prostaglandins, and engulf
(phagocytize) foreign substances
Inflammatory response
Physical barriers, such as intact skin, chemical barriers,
and acidic gastric secretions or enzymes in tears and
saliva
• Acquired immunity: specific against a foreign antigen
Result of prior exposure to an antigen
Active or passive
Development of Cells of the
Immune System
Lymphocytes
• B lymphocytes mature in the bone marrow; T lymphocytes mature in
the thymus where they also differentiate into cells with various
functions
Stages of Immune Response
Response to Invasion: Defenses
• Opsonization