Synthesis and Characterization

of PVA-Cellulose and PVA-

Rice Husk Ash Hydrogels
Ruth Naomi Mariae Rosales | Christian Carating
BACKGROUND OF STUDY
One of the three types of
gels

Made mostly of water (up
to 99%)

Degree of flexibility

http://img.chinamedevice.com/product/959/1443959.jpg
Background of Study
Applications

http://cdn.phys.org/newman/gfx/
news/2012/targetingdru.jpg
http://img.chinamedevice.c
om/product/959/1443959.jpg
http://media.materialsviews.com/wp-
content/uploads/2012/02/growing-
cartilage-cells-on-hydrogels-scaffolds-
300x199.jpg
BACKGROUND OF STUDY
Statement of the Problem

Develop a hydrogel from locally available
materials that has a possible use for biomedical
applications, specifically in drug-delivery systems

OBJECTIVES OF THE STUDY
To synthesize a high-strength hydrogel from
indigenous naturally derived materials (cellulose and
rice husk)

To observe the effect of cellulose and silica on the
properties of the hydrogel

To observe the possibility of usage of the hydrogel for
drug delivery applications


METHODOLOGY
Procureme
nt of
cellulose
Extraction
of silica
Synthesis of
PVA-
cellulose
Synthesis of
PVA-silica
ash
Characterization
Data
Analysis
METHODOLOGY
Extraction of Silica from Rice Husk Ash
Procureme
nt of rice
husk
Incineratio
n of rice
husk
250 g RHA
+ 1.5 L of 1
M NaOH
Boil for 1
hour with
constant
stirring
Filter
solution
Cool filtrate
to room
temperatur
e
Wash with
100 mL
boiling
water
METHODOLOGY
Synthesis of PVA-cellulose and PVA-silica
PVA
powder+
diH
2
O
Heat at 85
o

for 1 hour
Sodium silicate
solution/
cellulose +
diH
2
O
Heat at 85
o

for 1 hour
Mix through
mechanical
stirring
Oven dry
at 50
o
C for
10 hours
Add
alcohol and
store for 24
hours
Pour to
alcohol and
decant to
mold
After 1 hour,
cool to
room temp.
Add glutar-
aldehyde
METHODOLOGY
Characterization: Kinetics
Gelling
time
Swelling
rate
Matrix
degradation
METHODOLOGY
Characterization: Mechanical Properties
Indentatio
n testing
Tensile/co
mpression
testing
Rheometry
GANTT CHART
9/2/2014 9/22/2014 10/12/2014 11/1/2014 11/21/2014 12/11/2014
Finalization of research proposal
Thesis proposal writing
Materials procurement
Extraction of silica ash and cellulose
Synthesis of PVA based hydrogels
Characterization
Data analysis
Consultation
Manuscript Writing
Final Defense
Revisions
Manuscript Submission
REFERENCES
Princeton

An improved method for production of silica from
rice hull ash
Synthesis and Characterization
of PVA-Cellulose and PVA-
Rice Husk Ash Hydrogels
Ruth Naomi Mariae Rosales | Christian Carating