Epilepsy

Therapeutics

--Dr. K. John Paul

 Brief Description on Epilepsy
• A disorder characterized by excessive
hyper synchronous discharge of impulses
from the cerebral neurons

PATHOPHYSIOLOGY

EXCITATORY TRANSMITTORS INHIBITORY TRANSMITTORS

IMBALANCE

EPILEPSY
• CAUSES: • PRECIPITATING
FACTORS

Idiopathic o Pain
1.Increased intracranial o Emotional disturbance
pressure o Shock
2.Infections o Noise, music,
3.Trauma flickering light
4.Cerebrovascular o Sleep deprivation,
disease o Starvation
5.Congenital o Extreme fatigue
abnormalities o Premenstrual state
6.Degenerations o Fever
7.Anoxia o Alcohol
8.Exogenous & o Drugs
endogenous toxins
 EPILEPSY CLASSIFICATION

SIMPLE MOTOR
PARTIAL

COMPLEX SENSORY

VISUAL
PRIMARY
GENERALIZED VERSIVE

SECONDARY PSYCHOMOTOR

UNCLASSIFIED
TONIC CLONIC

CLASSICAL
ABSENCE
STATUS
EPILEPTICUS ATYPICAL
ABSENCE
• Epilepsy from suppressed Eruptions
-ASTERIAS [PSOR, SULPH, AGAR]
• Epilepsies, from valvular diseases of the heart
- CALC-ARS
• Epilepsy at puberty, during establishment of menstrual
functions
–CAULOPHYLUM [ACTAEA]
• Epilepsy, or Petit mal, after head injuries
–NATRUM SULPH
• Epilepsy from worms
–INDIGO & CINA
• Convulsions: acute, sudden, severe. prevail over trembling.
Epilepsy: petit or grand mal aggravated night of stone cutters
–CURARE
• Convulsions from teething in children, heat & jerks with
twitches of single muscles
-ACONITE
• Epileptic spasms with clenched thumbs, red face, eyes
turned downwards, pupils fixed, foaming in mouth
–AETHUSA
• Epileptic spasms while awake, ceases during sleep
–AGARICUS
• Convulsions in children from nursing, after a fit of
anger in mother
–CHAMOMILLA. [NUX-VOM]
• Convulsions in children from nursing, after a fright in
mother
– OPIUM
• Convulsions without consciousness
–BELL, CIC, HYOS, OP
• Convulsions during dentition with pale face, no heat,
except perhaps in occiput, no increase in temperature
–ZINC.MET
• Convulsions from teething in children without fever
–MAG.PHOS
• Convulsions from teething in children with fever
–BELL
• Convulsions with consciousness < emotion, touch,
moving
– NUX.VOM [STRYCH]
• Clonic, tonic spasms or epileptiform convulsions from
cerebral sclerosis or tumour
–PLUMB
• Convulsions from dazzling or reflected light from
water or mirror; from even thinking of fluids of any
kind or from slightest touch or current of air
–LYSSIN
• Convulsions with extreme coldness of the body,
except head or occiput which may be hot
–HELLEBORUS [ARN]
• Is possibly the best remedy, but always seek basic
causes. Worms and parasites are a frequent cause;
also marked endocrine imbalance and contraction in
vital organs
- PILOCARPUS
WITH AURA WITHOUT AURA
o Kali brom o Zinc val
o Cup met o Artem vulg
o Cup acet o Oenan croc PETIT MAL
o Calc ars o Plumb met o Artem
o Cimic o Aster rub Vulg
o Amm brom o Visc alb
o Zinc cyan
o Bufo rana
o Nat sil
o Nicotinum o Mag sil
o Silicea GRANDMAL
o Sil met
o Ononis o Kalibrom
o Kali Sil
o Bufo o Ferrum sil
o Merc o Caust
o Solanum carol o Phosph
o Hydrocyan acid o Cic vir
o Silicea
 CUPRUM METALLICUM
• Aura begins at knees, ascends to hypogastrium;
then unconsciousness, foaming, and falling.
• Spasmodic affections, cramps, convulsions, violent,
contractive, and intermittent pain, are some of the
more marked expressions of the action of Cuprum;
• Its curative range therefore includes tonic and
clonic spasms, convulsions, and epileptic attacks.
• Chorea brought on by fright.
• Nausea greater than in any other remedy.
• Face.-Distorted, pale bluish, with blue lips.
Contraction of jaws, with foam at mouth.
 SILICEA TERRA
• The aura starts from the solar plexus, as in Bufo and
Nux vom.
• Nocturnal epilepsy, feeling of coldness before an
attack and the fit is followed by warm perspiration
• The attacks occur about the time of the new moon
Bufo rana
• Epilepsy arising from fright, or self-abuse, or sexual
excesses
• The aura starts from the genital organs, solar
plexus, even during coitus the patient may be
seized with violent convulsions
• Previous to attacks, the patient is very irritable,
often talks incoherently and is easily angered
Indigo
• Has epileptiform convulsions from the irritation of
worms, but the patient must be low-spirited and sad
• It is the bluest medicine in the Materia Medica
 Cicuta virosa
• Sudden rigidity followed by jerks and violent distortions, and
these followed by utter prostration
• Loss of consciousness, great oppression of breathing
• lockjaw, face dark red, frothing at the mouth and opisthotonos
• Fixed staring eyes; others are trembling before and after the
spasm and strange feeling in the head preceding the attack.

Artemisia vulgaris
• Convulsive diseases of childhood and girls at puberty.
• Petit mal. Epilepsy without aura
• After fright and other violent emotions and after masturbation.
• Several convulsions close together. Colored light produces
dizziness
 ABSINTHIUM
• Nervous tremors precede attacks.
• Sudden and severe giddiness, delirium with
hallucinations and loss of consciousness.
• Nervous excitement and sleeplessness.
• Cerebral irritation, hysterical and infantile spasms come
within range of this remedy.
• Poisoning by mushrooms. Nervousness, excitement,
and sleeplessness in children. Spasmodic facial
twitching

OENANTHE CROCATA
• Epileptiform convulsions; worse, during menstruation
and pregnancy. Puerperal eclampsia; uraemic
convulsions. Convulsive facial twitching.
• Countenance livid, eyes fixed, pupils dilated, convulsive
twitching of facial muscles, trismus, foaming at mouth,
locked jaws.
• Extremities - Convulsions; opisthotonos. Cold hands and
feet. Numbness of hand and foot.
 HYDROCYANICUM ACIDUM
• One of the most toxic agents known. Convulsions
and paralysis express the action of this remedy.
• Spasmodic constriction in larynx, feeling of
suffocation, pain and tightness in chest
• Palpitation; pulse weak, irregular.
• Hysterical and epileptic convulsions. Cyanosis.
• Collapse, due to some pulmonary condition not a
cardiac collapse.
• Catalepsy. Cholera. Stage of collapse. [Ars.; Verat.]
• Coldness. Tetanus narcolepsy.

KALI BROM
• A palliative in true epilepsy
• Congenital epilepsy, syphilitic, tubercular
• A day or two before menses, new moon
• Headache follows attack
 Hyoscyamus
• There is much twitching and jerking and hunger
previous to the attack
• Frothing at the mouth and biting of the tongue.
• The convulsions seem to have more of a hysterical
nature and there are illusions of sight and hearing
• Epilepsy from fright, sudden loss of consciousness
and jerking of the head to the right, with rotary
motion of the left arm

Kali cyan
• Most frightful epilepsy repeated several times,
the day after an attack. Motionless (soon).
Sphincters paralyzed. Lazy and sleepy, and
disinclined to work, in the morning
 SOLANUM CAROLINENSE
•convulsions and epilepsy
•Is of great value in grand mal of
idiopathic type, where the disease has
begun beyond age of childhood;
•Hystero-epilepsy

EPILEPSY
Pilocarpus 30, Absinth. 30, Cicuta 30, Passiflora 30,
Ol. Cade 30, Lobelia E. 30, Arg. N. 30, Fucus 30, K.Brom.
30, Cuprum 30. K.P. 30, M.P. 30. P. 3,P. 49, P. 59