Professional Documents
Culture Documents
Part 1
• The Skeleton System
• Growth & Repair
• Axial Skeleton
• Appendicular Skeleton
• Articulations
Part 2
• Muscular System
• Skeleton Muscle Fiber Contractions
• Whole Muscle Contraction
• Muscular Disorders and Homeostasis
• The Skeleton System
• Growth & Repair
• Axial Skeleton
• Appendicular Skeleton
• Articulations
Pic from
Human Biology
Pg 210
Intramembranous ossification is the classification for bones that form between fibrous tissue.
During fetal development, osteoblasts are formed from connective tissue cells and release
osteoid, mixing with calcium salts to bring about calcification. The bone formation process
takes place in the spongy bone, where it is coated by a periosteum, compact bone forms and
encloses the spongy bone. This process is used in healing fractured bones.
Growth & Repair
Another way bone growth occurs is by endochondral ossification. Calcified bone matrix
replaces cartilage, and on the inside the bone forms from the center outward towards
the ends.
The above diagram shows the steps as follows: the chondrocytes (cells) lay down
hyaline cartilage; periosteum forms producing osteoblasts; the bone collar (compact
bone) is formed by osteoblasts releasing osteoid which undergoes calcification; blood
vessels transport the osteoblasts to the ossification center where spongy bone is
formed; osteoclasts absorb spongy bone creating the medullary cavity; the secondary
ossification centers are created in the epiphysis after birth; articular cartilage and
cartilage at the epiphyseal plate are present; the growth plate separates the primary
center from each secondary center and this accounts for longitudinal growth in children
Pic from http://en.wikipedia.org/wiki/Bone#Formation and adolescents.
Growth & Repair
Four distinct zones take place during endochondral ossification.
1. Resting Zone: next to epiphysis, contains cartilage
2. Proliferating Zone: chondrocytes undergo mitosis producing
new cells
3. Degenerating Zone: cartilage cells dye off
4. Ossification Zone: formation of bone
epiphysis
Bone remodeling is a term used to describe bone renewal, the constant bone breakdown by
osteoclasts and bone buildup by osteoblasts. This process helps maintain bone homeostasis,
keeping it strong. If bone is generated too fast (Paget’s Disease), it becomes soft and is
vulnerable to breakage and deformities. Blood calcium levels are regulated by parathyroid
hormone (speeds up bone recycling) and calcitonin (opposite PTH). Once one reaches about
middle age, a condition known as osteoporosis can set in. Osteoporosis is a decrease in bone
mass resulting in weakened and brittle bones. Exercise, calcium, and vitamin D can all help
Growth & Repair
After a bone is fractured the repair
process takes several months and 4
steps: hematoma, fibrocartilaginous
callus, bony callus, and remodeling.
Hematoma is an accumulation of
clotted blood and is the first step that
takes place to healing fractured bones.
After a fracture, blood vessels are
ruptured and blood accumulates in the
break of the bone for about seven
hours. The next step, fibrocartilaginous
callus, is when the tissue repair begins
to fill the fractured part of the bone.
This process takes about three weeks.
The third step, bony callus, takes
about three to four month to complete.
Trabeculae of spongy bone is formed
by osteoblasts and fibrocartilage callus
is transformed to bony callus to aid in
fusing the broken bones together. The
final step, remodeling, is the formation
of new compact bone by osteoblasts
and the absorption of spongy bone by
osteoclasts, The result is a new
Pic from Human Biology Pg 214
medullary cavity.
• The Skeleton System
• Growth & Repair
• Axial Skeleton
• Appendicular Skeleton
• Articulations
Axial Skeleton
Biology Pg 216
Pic from
The wrist contains 8 carpel bones; 5 are metacarpal
Human
Biology Pg
and spread out to form the palm part of the hands.
220 The fingers and thumb bones are known as the
phalanges.
Appendicular Skeleton
The pelvis is made of the pelvic girdle (large hip
bones known as coxal bones), sacrum, and coccyx,
attaches the legs, and bears body weight. The coxal
bones are made of the ilium (largest part, bigger in
women), the ischium (we sit on), and the pubis (both
pubis bones are joined by the pubic symphysis). The
acetabulum is the hip socket where the femur
(thighbone) joins with the coxal bone. The greater
trochanter at the top of the femur and the lesser
trochanter on the inside if the top of the femur allow
for muscle attachment. The femur ends in a medial
condyle and a lateral epicondyle which join the tibial
tuberosity (top of tibia). The area of connection is at
the patella, or kneecap. The smaller bone in the
lower leg is called the fibula; it attaches to the tibial
tuberosity and ends in the lateral malleolus at the
ankle. The medial malleolus is the end of the tibia
and accounts for the inside ankle bulge. The ankle
has 7 tarsal bones, the talus (one of the tarsal
bones) is attached to the tibia and fibula, and the
heal bone (calcaneus) which supports body weight.
The end of the 5 metatarsal bones form the ball of
the foot, and the ends of the feet are known as
phalanges, or toes.
Pic from Human
Biology Pg 221
• The Skeleton System
• Growth & Repair
• Axial Skeleton
• Appendicular Skeleton
This picture shows synovial
• Articulations joint movements.
Pic from
Human
Biology
Pg 223
Articulations
Bones are joined together at fibrous joints which aid in flexibility. The sutures are a
form of fibrous joints which are immovable in between cranial bones. Cartilaginous
joints have some flexibility. Synovial joints are the most flexible and are filled with
synovial fluid in the joint cavity. Above the cavity is articular cartilage and below is
menisci (sections of hyaline cartilage). Joints are supported by ligaments which are
responsible for connecting bones. Bursae are sacs filled with fluid that offer cushion
around joints and in areas between bones and muscles.
Synovial Joint