Professional Documents
Culture Documents
8,
August 2012, pp 26772686 DOI
10.1002/art.34473 2012, American College
of Rheumatology
Latar Belakang
Kasus
Kriteria
Tujuan
Metode
Tahap
Metode
Tahap
Validasi
Hasil
Tahap
derivasi
Dikatakan SLE jika pasien tsb memenuhi minimal 4 dari kriteria klinis dan
imunologi, yang didalamnya minimal 1 kriteria klinis dan 1 kriteria imunologi,
ATAU jika pasien tsb telah di biopsi ginjal dan terbukti lupus nefritik dengan
dibuktikan adanya ANA atau Anti dsDNA Antibodi
Hasil
Tahap
Validasi
Diskusi
Malar
Kriteria
Kriteria
Kriteria
Diskusi
Aspek
Kriteria
Sensitivity.
Identifies the proportion of people who test positive in a group of people known to have the
disease or condition, or the proportion of people who are true positives compared with the total
number of people who actually have the disease. When the observation or test is negative in people
with the disease, the result is termed false negative. Good observations or tests have a sensitivity of
more than 90%, and help rule out disease because there are few false negatives. Such observations or
tests are especially useful for screening.Example: The sensitivity of Homan's sign in the diagnosis of
deep venous thrombosis (DVT) of the calf is 50%. In other words, compared with a group of patients
with deep vein thrombosis confirmed by phlebogram, a much better test, only 50% will have a positive
Homan's sign, so this sign, if absent, is not helpful because 50% of patients may have a DVT.
Specificity.
Identifies the proportion of people who test negative in a group of people known to be
without a given disease or condition, or the proportion of people who are true negatives compared
with the total number of people without the disease. When the observation or test is positive in people
without the disease, the result is termed false positive. Good observations or tests have a specificity of
more than 90% and help rule in disease because the test is rarely positive when disease is absent,
and there are few false positives.Example: The specificity of serum amylase in patients with possible
acute pancreatitis is 70%. In other words, of 100 patients without pancreatitis, 70% will have a normal
serum amylase; in 30%, the serum amylase will be falsely elevated.