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Background
Although
Atherosclerotic
The Framingham
Study(1948) :
Prospective
The Framingham
Study(1948).
Identified factors:
Advanced age
Male sex
Diabetes
Elevated cholesterol
Hypertension
Cigarette smoking
Physical inactivity
INTERHEART :
INTERHEART
is a large, international,
standardised, case-control study,
designed as an initial step to assess
the importance of risk factors for
coronary heart disease worldwide
Objective
Methods:
Study
To
At
Hospitalbased
Procedures
Structured
questionnaires were
administered and physical examinations
were undertaken in the same manner in
cases and controls.
Information about demographic factors,
socioeconomic status (education, income),
lifestyle (smoking, leisure time, physical
activity, and dietary patterns), personal and
family history of cardiovascular disease, and
risk factors (hypertension, diabetes mellitus)
was obtained.
Psychosocial factors (depression, locus of
control, perceived stress, and life events)
were systematically recorded and integrated
into one score
Height,
Non-fasting
Samples
All
Current
The
Statistical analysis
Simple
PARs
Results
Between
Risk by age
583
Family history
Family
Discussion
This
The
Both
The
Smoking
Abnormal
South
Unanswered
While explaining the role of conventional risk
factors in the etiology of myocardial
questions
infarction, INTERHEART study also opens up
What
Limitations
First,
a casecontrol design is
potentially open to confounding if
there is differential ascertainment
of risk factors between cases and
controls
Second,
Third,
Fourth,
Fifth,
Strengths :
First,
Third,
Conclusion:
Nine
Online
risk calculator
https://rome.phri.ca/interheartris
kscore
Thank You