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MICROBIOLOGY
Microbiology
The scientific study of
microorganisms (microbes)
Microorganisms (microbes) organisms that are too small to be
seen by the unaided eye
Microbes help us by
decomposing organic waste
performing photosynthesis
producing ethanol, acetone, vinegar, cheese,
bread, . . .
Important Events in
Microbiology
1. Debate on Theories of origin of
living organism
2. Invention of the microscope
Theory of Abiogenesis
Life can emerge from ORGANIC
Before Microbiology
There was a belief in Theory of
Spontaneous Generation
- From the time of ancient Romans to the
late 19th century
- Living organism can arise spontaneously
from non-living substances
Theory of Biogenesis
- Living organisms can only come from preexisting life forms
Microbiology established
as a science
Louis Pasteur
Spontaneous generation disproved
Wine fermentation (yeasts and
bacteria)
Pasteurization
Pre-Pasteur:
Ignaz Semmelweis (1840s)
Lister (1860s)
antiseptic
32
33
Robert Koch
Work on anthrax proves the
postulates
Development of pure
culture technique
Modern Developments in
Microbiology
Bacteriology Mycology
Parasitology Virology
Immunology
Microbial genetics and molecular
Malaria transmission
1905
TB bacterium
1908
Phagocytes
1945
1952
1969
replication
1987
1997
2005
ulcers
Diphtheria antitoxin
Ross
Koch
Metchnikoff
Fleming, Chain, Florey
Penicillin
Waksman
Streptomycin
Delbrck, Hershey, Luria Viral
Tonegawa
Antibody genetics
Prusiner Prions
Marshall & Warren H. pylori &
Antimicrobial
resistance
Bioterrorism
(Re-)emerging infectious diseases (EID):
Examples
(S. pneumoniae)
1911
Types of Microorganisms
Bacteria
Archaea
Fungi
Protozoa
Algae
Viruses
Multicellular animal parasites
Prions
Bacterium / Bacteria
Prokaryotic
Peptidoglycan cell wall
Reproduction by binary fission
Archaea
Prokaryotic
No peptidoglycan
Live in extreme
environments
Include
Methanogens
Extreme halophiles
Extreme thermophiles
Figure
4.5b
Fungus/Fungi
Eukaryotic
Chitin cell walls
Use organic chemicals for energy.
Molds and mushrooms are
Protozoa
n/
Protozoa
Eukaryotes
Absorb or ingest organic
chemicals
May be motile via
Viruses
Are acellular
Have either DNA or
RNA in core
Coat may be enclosed in a lipid
envelope.
Viruses only replicate within a
Multicellular
Animal Parasites
Eukaryotes
Multicellular animals
Helminths are
parasitic flatworms
and round worms
Microscopic