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Presentasi Jurnal

I Made Restu Widiana

Public Acceptance and Willingness-to-Pay


for a Future Dengue Vaccine: A CommunityBased Survey in Bandung, Indonesia

Background: All four serotypes of dengue virus are


endemic in Indonesia, where the population at risk for
infection exceeds 200 million people. Despite
continuous control efforts that were initiated more than
four decades ago, Indonesia still suffers from multiannual cycles of dengue outbreak and dengue remains
as a major public health problem. Dengue vaccines have
been viewed as a promising solution for controlling
dengue in Indonesia, but thus far its potential
acceptability has not been assessed.

Public Acceptance and Willingness-to-Pay


for a Future Dengue Vaccine: A CommunityBased Survey in Bandung, Indonesia

Methodology/Principal Findings: We conducted a


household survey in the city of Bandung, Indonesia by
administering a questionnaire to examine (i) acceptance
of a hypothetical pediatric dengue vaccine; (ii)
participants willingness-to-pay (WTP) for the vaccine,
had it not been provided for free; and (iii) whether
people think vector control would be unnecessary if the
vaccine was available. A proportional odds model and an
interval regression model were employed to identify
determinants of acceptance and WTP, respectively.

Public Acceptance and Willingness-to-Pay


for a Future Dengue Vaccine: A CommunityBased Survey in Bandung, Indonesia

We demonstrated that out of 500 heads of household


being interviewed, 94.2% would agree to vaccinate their
children with the vaccine. Of all participants, 94.6%
were willing to pay for the vaccine with a median WTP
of US$1.94. In addition, 7.2% stated that vector control
would not be necessary had there been a dengue
vaccination program.

Public Acceptance and Willingness-to-Pay


for a Future Dengue Vaccine: A CommunityBased Survey in Bandung, Indonesia

Conclusions/Significance: Our results suggest that


future dengue vaccines can have a very high uptake
even when delivered through the private market. This,
however, can be influenced by vaccine characteristics
and price. In addition, reduction in community vector
control efforts may be observed following vaccine
introduction but its potential impact in the transmission
of dengue and other vector-borne diseases requires
further study.

Parental acceptance of human


papillomavirus (HPV) vaccination in
Indonesia: A cross-sectional study

Background: Cervical cancer ranks the second most


frequent cancer in Indonesian women. In Indonesia,
human papillomavirus (HPV) vaccine acceptance has not
been studied before.

Objective: To determine parental HPV vaccine


acceptance in Indonesia, and factors that influence
their decision. Factors include sociodemographic
factors, knowledge of HPV, HPV vaccination and cervical
cancer, health beliefs about cervical cancer, and
attitudes towards vaccination in general.

Parental acceptance of human


papillomavirus (HPV) vaccination in
Indonesia: A cross-sectional study

Methods: 746 parents, with at least 1 daughter aged 0


14, were interviewed using questionnaires based on
published and adjusted interviews. Interviews were
done in sub district public health centers, general
governmental hospitals, and via house-visits, in 5
Indonesian provinces.

Parental acceptance of human


papillomavirus (HPV) vaccination in
Indonesia: A cross-sectional study

Results: Parental HPV vaccine acceptance was 96.1%.


Logistic regression revealed that age, beliefs regarding
cervical cancer, and attitudes towards vaccination in
general were significantly associated with HPV vaccine
acceptance. Of the participants, 66.0%, 16.6%, and
15.8% had heard about cervical cancer, HPV, and HPV
vaccination respectively. The mean total knowledge
score was 1.91(Standard Deviation 2.31) on a 08 scale.
Health beliefs about cervical cancer and attitudes
towards vaccination in general were positive.
Participants named the high cost of the vaccine, fear
for side-effects, and chosen vaccination locations as
possible barriers towards HPV vaccine implementation.

Parental acceptance of human


papillomavirus (HPV) vaccination in
Indonesia: A cross-sectional study

Discussion: Parental HPV vaccine acceptance is high,


but knowledge about HPV and cervical cancer is low.
During HPV vaccination programs, focus should not only
be on providing information, but also on existing beliefs
and attitudes towards cervical cancer and vaccination in
general. If HPV vaccination programs were to be
implemented in Indonesia, the indicated barriers should
be taken into account.

Nasopharyngeal Carriage ofStreptococcus


pneumoniain Pneumonia-Prone Age Groups
in Semarang, Java Island, Indonesia

Introduction; Streptococcus pneumoniaeis a worldwide


occurring pathogen Nasopharyngeal carriage
ofStreptococcus pneumoniaeprecedes pneumonia and
other pneumococcal diseases in the community. Little is
known aboutS. pneumoniaecarriage in Indonesia,
complicating strategies to control pneumococcal
diseases. We investigated nasopharyngeal carriage ofS.
pneumoniaein Semarang, Indonesia.

Nasopharyngeal Carriage ofStreptococcus


pneumoniain Pneumonia-Prone Age Groups
in Semarang, Java Island, Indonesia

Methods; A population-based survey was performed in


Semarang, Indonesia. Nasopharyngeal swabs and
questionnaires were taken from 496 healthy young (660
month-old) children and 4570 year-old adults.

Results; Forty-three percent of children aged 660


months and 11% of adults aged 4575 years carriedS.
pneumoniae. Determinants of carriage were being a
child (OR 7.7; 95% CI = 4.513.0), passive smoking (OR
2.1; 95% CI = 1.33.4), and contact with toddler(s) at
home (OR 3.0; 95% CI = 1.94.7). The most frequent
serotypes found were 6A/B and 15B/C. The current
commercially available vaccines cover <50% serotypes
found in children. Twenty-four percent ofS.
pneumoniaestrains were penicillin non-susceptible, and
45% were resistant to cotrimoxazol.

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