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Introduction
Population aging is considered as the most serious problem in
developed countries and is going to be a threat for
developing countries.
Aging is associated with various physiological changes and
multiple diseases alter the pharmacological response to a
drug.
Moreover, elderly people are more sensitive to frequently
used drugs like NSAIDs, benzodiazepines, opioids etc.
All these factors alter the drug response resulting in adverse
drug reactions (ADRs) and hospitalization, consuming 40% of
health service expenditure in developed countries.
Principles of prescribing in
elderly
Conclusion
Drug therapy in older patients varies from that of adults due to:
Diagnosis.
treatment plan.
Prescription.
patient education.
dose adherence.
Conclusion
For appropriate and rational prescription in elderly patients
the following factors should be taken into account.
Prescribing in pregnant
women:
guide to general
principles
Introduction
Over 80 percent of women in the UK report taking
medications during their pregnancy.
Most will be unaware of the background risk of
congenital malformations and that their own risk of
having a baby with a congenital malformation may be
increased by exposure during pregnancy to some
medicines and chemicals.
Alcohol, nicotine, drugs of abuse and certain disease
states also increase the risk of congenital
malformations, as do some genetic factors.
Teratogenic effects
Key points
assess or reassess the need for medication in any
woman planning a pregnancy, or who becomes pregnant.
consider whether it is appropriate to try nondrug
measures.
review medical history & consider obstetric history and
family history of malformations.
balance risks of medication against benefit of treatment
on mother and fetus.
consider safety of medication (stage of pregnancy, route
of administration, dose)
Key points
use the lowest effective dose for the shortest
possible time.
monitor efficacy of medication throughout
exposure.
always assess risks and benefits on an individual
patient basis.
ensure the most up-to-date information is being
used.
patient counselling regarding drug exposure during
pregnancy.
References
Drug Therapy for the Elderly [Wehling 2013]
clinicians-handbook-of-prescription-drugs
www.elsevier.es
http://www.elsevier.es/en-revista-medicina-universitaria-304articulo-use-of-medications-on-the-90367606
www.japi.org
http://japi.org/july_2008/u_525.html
www.onlinelibrary.wiley.com
http://onlinelibrary.wiley.com/doi/10.1002/psb.578/pdf
Thank U