Professional Documents
Culture Documents
Presented by
Andi Geby N. Fonda C111 11 202
Ismail C111 11 337
Wilda Anggriani Ansar C111 11 378
RESIDENT:
dr. Evelyn
SUPERVISOR:
dr. Widya Widita, Sp.KK, M.Kes
INTRODUCTION
Molluscum Contagiosum often occurs on children
and young adult.
This disease causes papular and nodular lesion with
Molluscum body inside.
Molluscum Contagiosum is caused by Mollluscipox
genus virus which belongs to Poxviridae family.
DEFINITION
This disease is caused by virus belonging to Poxviridae
family and Molluscipox genus. The clinical lesion is
discrete papular with molluscum body inside.
This virus generally is only occurs on surface of the
skin and on mucous membrane.
ETIOLOGY
Molluscum Contagiosum
is caused by more than 4
Poxviridae viruses which
is connected such as MCV
I, MCV II, MCV III, and
MCV IV.
PATHOGENESIS
The virus replicates within the cytoplasm of
epithelial cells, and infected cells replicate at
twice baseline rate. There are MCV genes that
may contribute to an impaired immune response
to this virus including (1) homolog of a major
histocompatibiity class 1 heavy chain, which
may interfere with antigen presentation (2)
chemokine homolog that may inhibit
inflammation; and (3) a glutathione peroxide
homolog that may protect the virus from
oxidative damage by peroxides.
PATHOGENESIS
Virus
Moluscum
Contagiosu
m
Increasing of
proliferation
of the virus
inside the
cytoplasm of
epithelial cell
Growth of
epidermal
lobules
Molluscum
body
(diameter
25m )
Fibrous
septa
between
lobules
Inhibits
papilla
DIAGNOSIS
1. Anamnesis
Usually asymptomatic, but sometimes can
be itchy and pain if theres inflammation
and infection.
Clinical Findings:
Papul (can be a giant
molluscum, papul with much
bigger size)
Discrete
Surface as dome-like
Contain molluscum body
SUPPORTING EXAMINATION
Giemsa dye
Histopathology
PROGNOSIS
Patient will recover spontaniously, but
usually need a long time, for months until
years
DIFFERENTIAL DIAGNOSIS
Verruccae Vulgaris : HPV infection on the epidermis with skin
lesion such as papul, dome-like skin-colored nodul, rough
surface with demarcated, can be singular or in group.
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