Professional Documents
Culture Documents
Pulmonary Diseases
Diseases
Pulmonary
Pulmonary Diseases
Diseases &
& Disorders
Disorders
Pulmonary
Pulmonary Diseases
Diseases &
& Disorders
Disorders
Thoracic Bellows
Chest/Diaphragm Trauma
Pickwickian Syndrome
Guillian-Barre Syndrome
Myasthenia Gravis
COPD
Pulmonary
Pulmonary Diseases
Diseases &
& Disorders
Disorders
Tongue
Foreign Body Aspiration
Angioneurotic Edema
Maxillofacial, Larnygotracheal Trauma
Croup
Epiglottitis
Respiratory
Respiratory Emergencies:
Emergencies: Causes
Causes
Emphysema
Chronic Bronchitis
Asthma
Cystic Fibrosis
Pulmonary
Pulmonary Diseases
Diseases &
& Disorders
Disorders
Pulmonary
Pulmonary Diseases
Diseases &
& Disorders
Disorders
Pulmonary
Pulmonary Edema
Edema
Pulmonary
Pulmonary Edema:
Edema: Pathophysiology
Pathophysiology
Two Types
Cardiogenic (high pressure)
Non-Cardiogenic (high permeability)
Pulmonary
Pulmonary Edema
Edema
Cardiogenic
Cardiogenic Pulmonary
Pulmonary Edema:
Edema:
Etiology
Etiology
Pulmonary
Pulmonary Edema
Edema
High Permeability
Disrupted alveolar-capillary membrane
Membrane allows fluid to leak into the interstitial
space
Widened interstitial space impairs diffusion
Non-Cardiogenic
Non-Cardiogenic Pulmonary
Pulmonary Edema:
Edema:
Etiology
Etiology
Toxic inhalation
Near drowning
Liver disease
Nutritional deficiencies
Lymphomas
High altitude pulmonary edema
Adult respiratory distress syndrome
Pulmonary
Pulmonary Edema:
Edema: Signs
Signs &Symptoms
&Symptoms
Dyspnea on exertion
Paroxysmal nocturnal dyspnea
Orthopnea
Noisy, labored breathing
Restlessness, anxiety
Productive cough (frothy sputum)
Rales, wheezing
Tachypnea
Tachycardia
Management
Management of
of Non-Cardiogenic
Non-Cardiogenic
Pulmonary
Pulmonary Edema
Edema
Position
Oxygen
PPV / Intubation
CPAP
PEEP
Transport
Adult
Adult Respiratory
Respiratory Distress
Distress Syndrome
Syndrome
Pneumonia
Pneumonia
Pneumonia
Pneumonia
Pneumonia
Pneumonia
Atelectasis
Sepsis
VQ Mismatch
Hypoxemia
Pneumonia:
Pneumonia: Etiology
Etiology
Viral
Bacterial
Fungi
Protozoa (pneumocystis)
Aspiration
Presentation
Presentation of
of Pneumonia
Pneumonia
Management
Management of
of Pneumonia
Pneumonia
Oxygen
Rarely is intubation required
IV Access & Rehydration
B2 agonists may be useful
Antibiotics (e.g. Rocephin)
Antipyretics
Pneumonia:
Pneumonia: Management
Management
Pulmonary
Pulmonary Embolism
Embolism
Pulmonary
Pulmonary Embolism
Embolism
Pulmonary
Pulmonary Embolism:
Embolism:
Pathophysiology
Pathophysiology
Pulmonary
Pulmonary Embolism
Embolism (PE)
(PE)
A disorder of perfusion
Combination of factors increase probability of
occurrence
Hypercoagulability
Platelet aggregation
Deep vein stasis
Pulmonary
Pulmonary Embolism
Embolism (PE)
(PE)
Risk factors
Venostasis or DVT
Recent surgery or trauma
Long bone fractures (lower)
Oral contraceptives
Pregnancy
Smoking
Cancer
Pulmonary
Pulmonary Embolism:
Embolism: Etiology
Etiology
Most Common Cause = Blood
Clots
Vessel Wall Injury
Virchow
sTriad
Hypercoagulability
Venous Stasis
Pulmonary
Pulmonary Embolism:
Embolism: Etiology
Etiology
Other causes
Air
Amniotic fluid
Fat particles (long bone fracture)
Particulates from substance abuse
Venous catheter
Pulmonary
Pulmonary Embolism:
Embolism: Signs
Signs &
& Symptoms
Symptoms
Small Emboli
Rapid Onset
Dyspnea
Tachycardia
Tachypnea
Fever
Episodic = Showers
Evidence or history of thrombophlebitis
Consider early when no other cardiorespiratory
diagnosis fits
Pulmonary
Pulmonary Embolism:
Embolism: Signs
Signs &
& Symptoms
Symptoms
Larger Emboli
Pulmonary
Pulmonary Embolism:
Embolism: Signs
Signs &
& Symptoms
Symptoms
Pulmonary
Pulmonary Embolism:
Embolism: Signs
Signs &
& Symptoms
Symptoms
There are NO
assessment findings
specific to pulmonary
embolism
Pulmonary
Pulmonary Embolism:
Embolism: Management
Management
Circulation
IV, 2 lg bore sites
Fluid bolus then TKO; Titrate to BP ~ 90 mm Hg
Monitor ECG
Rapid transport
PE
PE Management
Management
Thrombolytics
Aspirin & Heparin (questionable if any benefit)
Pulmonary
Pulmonary Embolism
Embolism
If the patient is alive when you get
to them, that embolus isnt going to
kill them.
But the next one they throw
might!
Pleurisy
Pleurisy
Presentation
Presentation of
of Pleurisy
Pleurisy
Pleurisy
Pleurisy
Management
Based upon severity of presentation
Mostly supportive
Pulmonary
Pulmonary Diseases
Diseases &
& Disorders
Disorders
Obstructive
Obstructive Airway
Airway Disease
Disease
Asthma
Emphysema
Chronic Bronchitis
Obstructive
Obstructive Airway
Airway Diseases
Diseases
Asthma experienced by ~ 4 - 5 % of
Canadian population
Mortality rate increasing
Obstructive
Obstructive Airway
Airway Disease
Disease
Exacerbation Factors
Intrinsic
Stress (especially in adults)
URI
Exercise
Extrinsic
Cigarette Smoke
Allergens
Drugs
Occupational hazards
Obstructive
Obstructive Airway
Airway Disease
Disease
General Pathophysiology
Specific pathophysiology varies by disease
Obstruction in bronchioles
Smooth muscle spasm (beta)
Mucous accumulation
Inflammation
Obstructive
Obstructive Airway
Airway Disease
Disease
General Pathophysiology
Obstruction results in air trapping
Bronchioles usually dilate on inspiration
Dilation allows air to enter even in presence of
obstruction
Bronchioles tend to constrict on expiration
Air becomes trapped distal to obstruction
Emphysema
Chronic Bronchitis
(Rarely Asthma may result in COPD)
COPD:
COPD: Epidemiology
Epidemiology
Emphysema
Type A COPD
Emphysema:
Emphysema: Definition
Definition
Destruction of alveolar
walls
Distention of pulmonary
air spaces
Loss of elastic recoil
Destruction of gas
exchange surface
Emphysema:
Emphysema: Incidence
Incidence
Emphysema:Etiology
Emphysema:Etiology
Smoking
90% of all cases
Smokers 10x more likely to die of COPD than
non-smokers
Environmental factors
Alpha 1 antitrypsin deficiency
hereditary
50,000 to 100,000 cases
mostly people of northern European descent
Emphysema:
Emphysema: Pathophysiology
Pathophysiology
Emphysema:
Emphysema: Pathophysiology
Pathophysiology
Emphysema:
Emphysema: Signs
Signs and
and Symptoms
Symptoms
Emphysema:
Emphysema: Signs
Signs and
and Symptoms
Symptoms
Increased Thoracic AP
Diameter
(Barrel Chest)
Decreased lung/heart
sounds
Hyperresonant chest
Emphysema:
Emphysema: Signs
Signs and
and Symptoms
Symptoms
PINK PUFFER
Chronic Bronchitis
Type B COPD
Chronic
Chronic Bronchitis:
Bronchitis: Definition
Definition
Chronic
Chronic Bronchitis:
Bronchitis: Incidence
Incidence
Chronic
Chronic Bronchitis:
Bronchitis: Etiology
Etiology
Smoking
Environmental irritants
Chronic
Chronic Bronchitis:
Bronchitis: Pathophysiology
Pathophysiology
Chronic
Chronic Bronchitis:
Bronchitis: Pathophysiology
Pathophysiology
Hypoxemia leads to
increased RBCs w/o oxygen which leads to
cyanosis
Hypercarbia leads to
pulmonary vascular constriction which leads to
increased right ventricular work which leads to
right heart failure which may progress to
cor pulmonale
Chronic
Chronic Bronchitis:
Bronchitis: Signs
Signs and
and
Symptoms
Symptoms
Chronic
Chronic Bronchitis:
Bronchitis: Signs
Signs and
and
Symptoms
Symptoms
COPD
COPD Assessment
Assessment Findings
Findings
COPD:
COPD: Management
Management
Causes of Decompensation
Respiratory infection (increased mucus
production)
Chest trauma (pain discourages coughing or deep
breathing)
Sedation (depression of respirations and
coughing)
Spontaneous pneumothorax
Dehydration (causes mucus to dry out)
COPD:
COPD: Management
Management
Oxygen
Dont withhold
Maintain O2 saturation above 90 %
COPD:
COPD: Management
Management
Ventilation
Avoid intubation unless absolutely necessary
near respiratory failure
exhaustion
Circulation
IV TKO
Titrate fluid to degree of dehydration
250 cc trial bolus
COPD:
COPD: Management
Management
Drug Therapy
Obtain thorough medication history
Nebulized Beta 2 agonists
Albuterol
Terbutaline
Metaproterenol
Isoetharine
COPD: Management
REMEMBER
All bronchodilators are
potentially arrhythmogenic
COPD:
COPD: Management
Management
Drug Therapy
Ipratropium (anticholinergic) by SVN
(beta-2 agonist) by MDI, SQ or IV
Corticosteroids (anti-inflammatory agent) by IV
COPD:
COPD: Management
Management
Avoid
Sedatives
Restlessness = hypoxia
Antihistamines
Dry secretions, decrease LOC
Epinephrine
Myocardial ischemia, arrhythmias
Intubation
difficult to wean off ventilator
Asthma
Asthma:
Asthma: Definition
Definition
Asthma:
Asthma: Incidence
Incidence
Asthma
Asthma
Diagnosis
H&P, Spirometry
Hx or presence of episodic symptoms of
airflow obstruction
airflow obstruction is at least partially
reversible
alternative diagnoses are excluded
Asthma
Asthma
Chronic bronchitis
Recurrent croup
Recurrent URI
Recurrent pneumonia
Asthma
Asthma
Cold temperature
Respiratory Infections
Vigorous exercise
Emotional Stress
Environmental allergens or irritants
Exacerbation
Extrinsic common in children
Intrinsic common in adults
Asthma
Asthma Pathophysiology
Pathophysiology
Asthma triggered
Bronchial smooth muscle contraction
Increased mucus production
Bronchial plugging
Relative dehydration
Alveolar hypoventilation
Ventilation Perfusion Mismatch
CO2 retention
Air Trapping
Asthma:
Asthma: Pathophysiology
Pathophysiology
Bronchospasm
Bronchial Edema
Increased Mucus
Production
Asthma:
Asthma: Pathophysiology
Pathophysiology
Asthma:
Asthma: Pathophysiology
Pathophysiology
Cast of airway produced by
asthmatic mucus plugs
Asthma:
Asthma: Pathophysiology
Pathophysiology
Difficulty exhaling
chest hyperinflation
Increased respiratory
water loss
dehydration
Asthma:
Asthma: Types
Types
Type 1 Extrinsic
Asthma:
Asthma: Types
Types
Adults < 35
Long term exposure to irritants
More inflammation than Type 1 Extrinsic
Does not respond well to bronchodilators
Needs treatment with corticosteroids
Asthma:
Asthma: Types
Types
Intrinsic Asthma
Adult > 35
No immunologic cause
Aspirin sensitivity/nasal polyps
Poor bronchodilator response
Asthma:
Asthma: Signs
Signs and
and Symptoms
Symptoms
Asthma:
Asthma: Signs
Signs and
and Symptoms
Symptoms
Tachycardia
Pulsus paradoxus in severe attacks
Anxiety, restlessness (hypoxia) progressing to
drowsiness, confusion (hypercarbia)
Asthma:
Asthma: Signs
Signs and
and Symptoms
Symptoms
WHY?
Asthma:
Asthma: Signs
Signs and
and Symptoms
Symptoms
IMPENDING
RESPIRATORY
FAILURE
Asthma:
Asthma: Signs
Signs and
and Symptoms
Symptoms
RESPIRATORY
FAILURE
Asthma:
Asthma: Risk
Risk Assessment
Assessment
Asthma:
Asthma: Management
Management
Airway
Breathing
Sitting position or position of comfort
Humidified O2 by NRB mask
Dry O2 dries mucus, worsens plugs
Encourage coughing
Consider intubation, assisted ventilation
Impending respiratory failure
Avoid if at all possible
Asthma:
Asthma: Management
Management
Circulation
IV TKO
Assess for dehydration
Titrate fluid administration to severity of
dehydration
Trial bolus of 250 cc
Asthma:
Asthma: Management
Management
Asthma:
Asthma: Management
Management
Nebulized anticholinergics
Ipratropium
Atropine
IV Corticosteroid
Methylprednisolone
Combination Flovent/etc
Asthma:
Asthma: Management
Management
Rarely used
Questionable efficacy, Potential Complications
Asthma:
Asthma: Management
Management
Asthma:
Asthma: Management
Management
Asthma:
Asthma: Management
Management
Avoid
Sedatives
Depress respiratory drive
Antihistamines
Decrease LOC, dry secretions
Aspirin
High incidence of allergy
Asthma:
Asthma: Management
Management
Asthma:
Asthma: Management
Management
Transport Considerations
How severe is the episode?
Is the patient improving?
How extensive (invasive) were the required
therapies?
What does he/she normally do after treatment?
Medical Control or PMD consult
Drug
Drug Delivery
Delivery Methods:
Methods: Review
Review
MDI vs. MDI w/ spacer vs. SVN
vs. SQ injection
Status Asthmaticus
Asthma unresponsive to beta-2
adrenergic agents
Status
Status Asthmaticus
Asthmaticus
Golden
Golden Rule
Rule
ALL THAT WHEEZES IS NOT
ASTHMA
Pulmonary edema
Pulmonary embolism
Allergic reactions
COPD
Pneumonia
Foreign body aspiration
Cystic fibrosis
Cystic Fibrosis
Cystic
Cystic Fibrosis:
Fibrosis: Definition
Definition
Cystic
Cystic Fibrosis:
Fibrosis: Etiology
Etiology
Cystic
Cystic Fibrosis:
Fibrosis: Pathophysiology
Pathophysiology
Hyperventilation Syndrome
Hyperventilation
Hyperventilation Syndrome
Syndrome
A diagnosis of EXCLUSION!!!
An increased ventilatory rate that
DOES NOT have a pathologic origin
Results from anxiety
Hyperventilation
Hyperventilation Syndrome:
Syndrome:
Pathophysiology
Pathophysiology
Tachypnea or hyperpnea
secondary to anxiety
Decreased PaCO2
Respiratory alkalosis
Vasoconstriction
Hypocalcemia
Decreased O2
Release to
Tissues
Hyperventilation
Hyperventilation Syndrome:
Syndrome:
Signs
Signs &
& Symptoms
Symptoms
Symptoms
Light-headedness, giddiness, anxiety
Numbness, paresthesias of:
Hands
Feet
Circumoral area
Hyperventilation
Hyperventilation Syndrome:
Syndrome:
Signs
Signs &
& Symptoms
Symptoms
Signs
Rapid breathing
Cool & possibly pale skin
Carpopedal spasm
Dysrhythmias
Sinus Tachycardia
SVT
Sinus arrhythmia
Hyperventilation
Hyperventilation Syndrome:
Syndrome:
Management
Management
Hyperventilation Syndrome
Serious diseases can mimic
hyperventilation
Laryngotracheobronchitis
Laryngotracheobronchitis (Croup)
(Croup)
Common syndrome of
infectious upper airway
obstruction
Viral infection
parainfluenza virus
Subglottic Edema
larynx, trachea,
mainstem bronchi
Usually 3 months to 4
years of age
Croup:
Croup: Signs
Signs &
& Symptoms
Symptoms
Hoarseness
Cough
Seal Bark Cough
Brassy Cough
Croup:
Croup: Signs
Signs &
& Symptoms
Symptoms
Croup:
Croup: Management
Management
Croup:
Croup: Management
Management
If in respiratory distress:
Racemic epinephrine via nebulizer
Decreases subglottic edema (temporarily)
Necessitates transport for observation for rebound
Epiglottitis
Epiglottitis
Bacterial infection
(Hemophilus
influenza )
Edema of epiglottis
(supraglottic)
partial upper airway
obstruction
Typically affects 3-7
year olds
Epiglottitis:
Epiglottitis: Presentation
Presentation
Fever
Severe sore throat
Dysphagia
Muffled voice
Drooling
Epiglottitis:
Epiglottitis: Presentation
Presentation
Respiratory difficulty
Stridor
Usually in an upright, sitting, tripod position
Epiglottitis:
Epiglottitis: Management
Management
Immediate life threat (8-12% die
from airway obstruction)
Epiglottitis:
Epiglottitis: Management
Management
Upper
Upper Respiratory
Respiratory Infection
Infection
Common illness
Rarely life-threatening
Often exacerbates underlying pulmonary
conditions
May become more significant in some
patients
Immunosuppressed
Elderly
Chronic pulmonary disease
Upper
Upper Respiratory
Respiratory Infection
Infection
Prevention
Avoidance is nearly impossible
Too many potential causes
Temporarily impaired immune system
Pathophysiology
Pathophysiology of
of URI
URI
Presentation
Presentation of
of URI
URI
Symptoms
Sore throat
Fever
Chills
HA
Signs
Cervical adenopathy
Erythematous pharynx
Positive throat culture (bacterial)
Management
Management of
of URI
URI
Central
Central Respiratory
Respiratory Depression
Depression
Respiratory
Respiratory Depression:
Depression: Causes
Causes
Head trauma
CVA
Depressant drug toxicity
Narcotics
Barbiturates
Benzodiazepines
ETOH
Respiratory
Respiratory Depression:
Depression:
Recognition
Recognition
Use Your
Stethoscope
THEY
PROBABLY
ARENT
Respiratory
Respiratory Depression:
Depression:
Management
Management
Airway
Open, clear, maintain
Consider endotracheal intubation
Respiratory
Respiratory Depression:
Depression:
Management
Management
Breathing
Oxygenate, ventilate
Restore normal rate, tidal volume
Respiratory
Respiratory Depression:
Depression:
Management
Management
Circulation
Obtain vascular access
Monitor EKG (Silent MI may present as CVA)
Manage Cause
Check Blood Sugar
Consider Narcan 2mg IV push if S/S suggest
narcotic overdose
Guillian-Barre
Guillian-Barre Syndrome
Syndrome
Autoimmune disease
Leads to inflammation and degeneration of
sensory and motor nerve roots (demyelination)
Guillian-Barre
Guillian-Barre Syndrome
Syndrome
Management
Management
Control airway
Support ventilation
Oxygen
Transport in cases of respiratory depression,
distress or arrest
Myasthenia
Myasthenia Gravis
Gravis
Autoimmune disease
Causes loss of ACh receptors at
neuromuscular junction
Attacks the ACh transport mechanism at the
NMJ
Myasthenia
Myasthenia Gravis
Gravis Presentation
Presentation
Myasthenia
Myasthenia Gravis
Gravis Management
Management
Treat symptomatically
Watch for aspiration
May require assisted ventilations
Assess for Pulmonary infection
Transport based upon severity of
presentation
Case Studies
Case
Case One
One
Case
Case One
One
Initial Assessment
Airway: Open, maintained by patient
Breathing: Rapid, deep, regular; no accessory
muscle use or retractions
Circulation: Radial pulses present, rapid, full; Skin
warm, dry; capillary refill < 2 seconds
Disability: Awake, alert, anxious
Case
Case One
One
Vital Signs
P: 126 strong, regular
R: 26 deep, regular
BP: 130/82
Physical Exam
Chest: BS present, equal bilaterally; no
adventitious sounds
Extremities: Equal movement in all
extremities; no weakness; hands cool
Oxygen saturation: 98%
Case
Case One
One
History
Allergies: NKA
Medications: Birth control pills
Past History: No significant past history; no
history of smoking
Last Meal: Lunch 2 hours ago
Events: S/S began suddenly after argument
with supervisor
Case
Case One
One
Case
Case Two
Two
Case
Case Two
Two
Initial Assessment
Airway: Inspiratory stridor audible
Breathing: Rapid, shallow, labored
Circulation: Radial pulses present, rapid, weak;
skin pale, hot, diaphoretic; capillary refill is 2
seconds
Disability: Awake, alert, obviously frightened and in
acute distress
Case
Case Two
Two
Vital Signs
P: 130 weak, regular
R: 32 shallow, regular with stridor
BP: 110/70
Physical Exam
HEENT: Flaring of nostrils; accessory muscle
use on inspiration; drooling present
Chest: BS present, equal bilaterally; no
adventitious sounds
Oxygen saturation: 92%
Case
Case Two
Two
History
Allergies: NKA
Medications: None
Past History: No significant past history
Last Meal: Dinner at about 1800 hours
Events: Awakened with severe sore throat. Has
experienced increasing difficulty breathing. Will
not eat or drink. Says it hurts to swallow
Case
Case Two
Two
Case
Case Three
Three
Case
Case Three
Three
Initial Assessment
Airway: Open, maintained by patient, mild stridor
audible
Breathing: Rapid, shallow, labored
Circulation: Radial pulses present, weak, regular;
Skin pale, warm, moist; Capillary refill <2 seconds
Disability: Awake, sitting up in bed, looks tired and
miserable
Case
Case Three
Three
Vital Signs
P: 100 weak, regular
R: 30 shallow, labored with stridor
BP: 90/50
Physical Exam
HEENT: Use of accessory muscles present; no
drooling
Chest: BS present, equal bilaterally with no
adventitious sounds. Auscultation difficult
because of stridor and barking cough
Case
Case Three
Three
History
Allergies: NKA
Medication: Tylenol for fever before bedtime
Past history: No significant past history
Last meal: Dinner around 1800 hours
Events: Patient has had cold for about 3 days.
Reasonably well during day. Awakens around
midnight with high-pitched cough that sounds
like a dog barking
Case
Case Three
Three
Case
Case Four
Four
Case
Case Four
Four
Initial Assessment
Airway: Open, maintained by patient, difficulty
swallowing, voice is hoarse
Breathing: Rapid, labored
Circulation: Radial pulses present, strong, regular;
Skin flushed; Capillary refill < 2 seconds
Disability: Awake, alert, very anxious
Case
Case Four
Four
Vital Signs
P: 120 strong, regular
R: 26 regular, slightly labored
BP: 118/90
Physical Exam
HEENT: Puffiness around eyes; Lips appear swollen;
Mild accessory muscle use
Chest: BS present, equal bilaterally; No adventitious
sounds
Urticaria on upper chest, extremities
Oxygen saturation: 94%
Case
Case Four
Four
History
Allergies: No drug allergies; Has experienced
itching previously when eating shrimp
Medications: None
Past history: No significant past history; no
history of smoking
Last meal: In progress at time of call
Events: Began to experience itching and
difficulty swallowing after eating fish and
chips
Case
Case Four
Four
Case
Case Five
Five
Case
Case Five
Five
Initial Assessment
Airway: Controllable with manual positioning
Breathing: Very slow, shallow
Circulation: Radial pulses present, weak; Skin
pale, cool, moist; Capillary refill 3 seconds
Disability: Unconscious, unresponsive to painful
stimuli
Case
Case Five
Five
Vital Signs
P: 70 regular, weak
R: 4 shallow, regular; alcohol odor on breath
BP: 100/70
Physical Exam
Case
Case Five
Five