WHAT YOU NEED TO KNOW

Why get vaccinated?

Dengue is one of the leading causes of

illness in the Philippines. Worldwide.
Philippines rank 7th among countries and
territories with the highest average
number of Dengue cases reported to the
World Health Organization (WHO) and 4 th
overall for the Asia Pacific region from
2004 to 2010.

Why get vaccinated?

DENGUE
Is a diseased caused by a dengue virus
transmitted by an infected female Aedes mosquito
Signs and symptoms: Fever (>2 days), skin
flushing, bleeding of nose or gums, loss of
appetite, nausea, vomiting

DENGVAXIA (DENGUE VACCINE)

What is DENGUE VACCINE?
Used to help protect a child against dengue
caused by dengue virus serotype 1,2,3, and
4.
It works by stimulating your bodys natural
defenses (immune system) which produces
its own protection (antibodies) against the
virus that causes dengue disease.

DENGVAXIA (DENGUE VACCINE)

Live, attenuated vaccine & contains 4 dengue virus serotypes-1,2,3,
and 4
Preparation : 5-dose per vial (multi-dose), suspension for SQ injection
NO vaccine vial monitor (VVM) label
Indicated for use to children and adults from 9 years to 45 years old
Tetravalent vaccine

DENGVAXIA (DENGUE VACCINE)

How many times should an individual get
vaccinated?
Given every 6 months.
For Example if one gets the first dose in April, the person
will receive his second dose 6 months after, which is
October. The third
dose will MONTH
be given 6 months after the
DOSES
second dose which is April of the
S following year.
1st dose
0
2nd dose
6
3rd dose
12

DENGVAXIA (DENGUE VACCINE)

Is the Vaccine effective to prevent dengue disease?
Yes. Based on the clinical studies conducted in 10 countries across Southeast
Asia and Latin America, the vaccine has been shown to be effective in:
Preventing severe dengueby 93.2%
Preventing hospitalized form of dengue by 80.8%
Preventing dengue due to any serotype by 65.6%.
As with the vaccines, the dengue vaccine may not protect 100% the person
who have been vaccinated.
Dengue vaccination is not a substitute for the protection against mosquito
bites and vaccinees are still encouraged to take appropriate precautions to
prevent mosquito bites.
Student beneficiaries will receive the vaccine during a school based
immunization program in all public schools scheduled on April 2016 for free.

DENGVAXIA (DENGUE VACCINE)

Does it cost anything (payment)?
DOH and DepEd is implementing the
dengue vaccination program for Grade 4
students aged 9 years old and above,
enrolled in the School Year 2015-2016.
Student beneficiaries will receive the FREE
vaccine during a school based immunization
program in all public elementary schools
scheduled on April 2016 for FREE.

DENGVAXIA (DENGUE VACCINE)

Where can we get the vaccine?
Vaccine will be available for grade 4 students 9
years old and above, enrolled in the School Year
2015-2016 at the time of the vaccination in all
public elementary schools during a school based
immunization program scheduled in April.
Those who will not be eligible for this
vaccination program may ask their physician on
how they can get vaccinated against dengue.

DENGVAXIA (DENGUE VACCINE)

Who should receive the vaccine?
All 9 years old male and female students enrolled in
Grade 4 public schools (SY 2015-2016) shall be vaccinated
with 3 doses of the Dengue tetravalent vaccine following
the recommended immunization schedule interval.
Only students with signed notification and consent letter
shall be vaccinated.
In case of dengue vaccination refusal or the student
received only one or two doses of dengue vaccines,
he/she shall not be suspended, grounded or reprimanded.

DENGVAXIA (DENGUE VACCINE)

Will it be distributed nationwide? If not, how
did you consider the priority places?
Dengue vaccination program of the DOH will only
be available in the regions in the Philippines with
the highest number of dengue cases annually
namely Region III, NCR, and Region IV-A from April
2016-2017.
Nevertheless, the vaccine will be available
nationwide in the private sector. Please ask your
physicians on how to access the vaccines.

DENGVAXIA (DENGUE VACCINE)

Who should not receive the vaccine(pregnant, allergies and other
diseases)?
The vaccine should NOT be given to the following:
Children less than 9 years old and adults older than 45
Individuals who have known allergies to active substances in the vaccine
Individuals weakened immune system due to genetic defect, HIV
infection, or therapies that affect the immune system such as high dosecorticosteroids or chemotherapy.
Pregnant or breastfeeding mothers;
Individuals suffering from a disease with mild to high fever or acute
disease(the vaccine can be given once the individual has recovered)

DENGVAXIA (DENGUE VACCINE)

If someone had already dengue, can they still avail
the vaccine?
Yes. Dengue disease is caused by 4 serotypes. Natural
infection caused by one of the 4 serotypes confers lifelong
immunity from that only serotype but not from the other
serotypes. Dengue vaccination can still provide protection
against dengue disease.
The vaccine has to be administered at least 3-6 months
from the acute episode of dengue. Like all medicines, the
dengue vaccine can cause side effects but it is manageable.

DENGVAXIA (DENGUE VACCINE)

What are the possible side effects from being vaccinated? What are the
cures for these?
Like all medicines, the dengue vaccine can cause side effects but it is
manageable.
Serious Allergic Reactions:
If any of these symptoms occur after leaving the place where your child received
the injection, you must consult a doctor IMMEDIATELY:
Difficulty of Breathing
Blueness of tongue or lips
Low blood pressure causing dizziness or collapse
Swelling of the face or throat
A rash
When these signs or symptoms occur they usually develop quickly after the
injection is given while the vaccinee (individual) is still in the vaccination area.
Serious allergic reactions are very rare, (may affect up to 1 in 10,000 people)
after receiving any vaccine.

DENGVAXIA (DENGUE VACCINE)

Other side effects:
The following side effects were reported during the clinical studies in children, adolescents and
adults. Most of the reported side effects occurred within 3 days after injection of the vaccine.

Very Common
(May affect more than 1 user
in 10)
Headache
Generally feeling unwell
Injection site pain
Muscle pain
Fever
Feeling of weakness

Common
(May affect up to 1 user in 100)
Injection site: reactions redness, bruising, swelling,
and itching
Uncommon
Infections of the upper respiratory tract
Dizziness
Cough
Nausea
Sore Throat
Runny nose

If the vaccinee experience any side effects after

vaccination, they are advised to seek immediate medical
attention

GENERAL GUIDELINES

DOH shall provide the necessary vaccines and other

immunization logistics (e.g. N/S, safety collector boxes,
immunization cards, recording and reporting forms) following the
routine system of the distribution of the immunization logistics.
Department of Education (DepEd) shall determine the most
appropriate timing of the immunization sessions, inform
teachers/parents/students of the vaccination, provide additional
human resource for vaccination, and ensure each eligible student
vaccinated and appropriately refer missed students for
vaccination.
The Local Government Units (LGUs) health personnel (MDs.
Nurses, midwives, volunteers) shall lead the vaccination in
collaboration with schools, hospitals and other partners within
the catchment areas.

VACCINATION STRATEGY
What is the vaccination strategy?
School-based, classroom per classroom
Rollingphase
When?
Starting April 2016 up to June 2017
April offer protection to the target population before the PEAK
SEASON
Number of vaccination rounds?
3 Rounds
Round 1 (Dose 1) : Year 2016 -April, May, June
Round 2 (Dose 2) : Year 2016 - October, November, December
Round 3 (Dose 3) : Year 2017 - April, May, June

Specific Guidelines:

Target Eligible Students

ALL 9 years old and above students
enrolled in Grade 4 public schools (SY
2015-2016) with consent in Regions NCR,III
and IVA (except participating students in
clinical study from San Pablo City, Laguna.
Grade 4 student aged less than 9 years old : DO NOT
GIVE DENGUE VACCINE

Specific Guidelines:

Target Eligible Students

All vaccinators shall conduct a quick health assessment of every eligible
students beforeASK
vaccination.
if the student had/has :
ACTIONS REQUIRED, if present
Fever
Cough
Rashes
Headache
Received any vaccine for the last 1
month
Enrolled in Dengue clinical study
from San Pablo City, Laguna
Recipient of blood products for the
last 3 months
With history of allergy to previous
dose
Taking corticosteroids or
chemotherapy
Pregnant or Breastfeeding

If any is present, DEFER

vaccination
until child is well.
Refer for medical management.
Set a definite date for the
vaccination.

DO NOT GIVE the dengue

vaccine.

Specific Guidelines:
Schedule of Administration of Dengue
Vaccines

All eligible students shall be vaccinated with the dengue

vaccine, 0.5ml, subcutaneous, (SC) at the LEFT deltoid
arm following the recommended vaccination schedule:
First Dose :
At time of visit with the healthworker, at 9
or
10 years old
Second Dose
:
At least 6 months after the 1st dose
Third Dose :
At least 6 months after the 2nd dose
NOTE: Health workers must ensure that those who
received the dengue vaccine first dose shall be given the 2nd
dose after 6
months and the 3rd dose 6 months after the 2nd
dose

Specific Guidelines:
Follow-up of Deferred Eligible
Students
Teacher-in-charge shall follow-up the deferred
students but willing to be vaccinated and refer to the
catchment health facility.
Students who will be referred and vaccinated at the
health facility shall be accompanied by the school
nurse and shall be included in the accomplishment
report as vaccinated.

Specific Guidelines:
Before Vaccination

Clinic/school nurses/teachers shall list all the enrolled students in Grade 4

using the Recording Form 1 (Masterlist of Grade 4 ).
All clinic/Grade 4 teachers/school nurses shall issue a notification letter
indicating the following:
3 doses of Dengue
Schedule of Vaccination
All clinic/Grade 4 teachers/school nurses shall ensure the retrieval of the
signed notification and consent form.

Specific Guidelines:
Adverse Event Following Immunization
(AEFI)
Fear of injections resulting to fainting has been commonly observed in
school immunization. Thus it is recommended that the vaccination sites are
situated in areas not conspicuous to the students. Immunization session
shall be conducted after recess to ensure that these eligible students have
taken their snacks/food to rule-out fainting secondary to hypoglycemia.

Adverse Events after the receipt of the vaccines, even if it is not clear that
the vaccine caused the adverse events should be reported following the
existing DOH Issuance Administrative Order No. 2010-0017, Guidelines in
Surveillance and Response to Adverse Events Following Immunization (AEFI).
However, a linelist of the minor reactions shall be recorded and submitted to
gather information on the various AEFI rates for the Philippines setting.

Specific Guidelines:
After Vaccination
All vaccinators shall provide all the students with key
messages on
Expected reactions after vaccination
Where to report in case of any vaccine reaction
Issue an immunization card
Indicate the specific dates of next doses

Mild and Temporary Reactions

FAINTING

Due to fear of injection, or sight of blood, or

having not eaten prior to immunization.
May last for a minute or less.
Keep the child lying down with her feet slightly
elevated.
If the symptoms persist, it may require
immediate attention. Bring the child to the
nearest health facilities.

SWELLING

Apply alternately cold and warm compress every

15 minutes using clean cloth until swelling
disappears in the injection site.
Do not massage the injection site.

RECORDING
AND
REPORTING
FORMS

Recording Form1: Masterlisting

Reporting Form1: Daily Reporting Form

Reporting Form2: Daily Consolidation

Form

Reporting Form3: Weekly Consolidation Form

Flow of Reporting/Deadline
School
RHU
Province/City
Regional DOH
National DOH

Preimplementation
Notification/Consent
Masterlist
Implementation
Weekly accomplishment
Final accomplishment per
round
AEFI

Flow of Reporting/Deadline
(Notification/Consent and Masterlist)
School (March 9, 2016) School Nurse
RHU/Municipality (March 11, 2016) - EPI
Coordinator
Province/City (March 16, 2016) EPI
Coordinator
Regional DOH (March 22, 2016) EPI/Dengue
Coordinator

Flow of Reporting/Deadline of Accomplishment

starting April 1
School (everyday before 12pm) Vaccination
Team
RHU/Municipality (everyday before 2pm) - EPI
Coordinator
Province/City (everyday before 4pm) EPI
Coordinator
Regional DOH (everyday before 5pm)
EPI/Dengue Coordinator

THANK YOU