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BTY100-Lec#4.

2
DNA to Protein (Central Dogma)
Created By:
Mamta Sharma
LPU : BTY100

Outline
Gene
Central Dogma: DNA to Protein
Replication
Transcription
Translation

LPU : BTY100

GENE
A Gene is a segment of DNA and is located on the
chromosome.
Gene specifies the structure of particular protein
that make up each cell.

LPU : BTY100

Structure of Gene
Composed of
Exons

Introns(absent
in prokaryotes)

Control
elements

LPU : BTY100

Parts of
Gene

Exon Coding sequence


Intron Non coding sequence
Only present in Eukaryotes!!
LPU : BTY100

Central Dogma: DNA to


Protein

LPU : BTY100

DNA Replication
Process of producing
two identical replicas
from one original DNA
molecule.
It occurs with the help
of
a
lot
of
enzymes/catalyst.
LPU : BTY100

Transcription: Process of Formation of RNA


from DNA

LPU : BTY100

TRANSLATION:
Process by which
RNA (mRNA) produced by
transcription is decoded by a
ribosome complex to produce a
protein

Example?
??.

LPU : BTY100

TRANSLATION

LPU : BTY100

Amino Acid Chain

LPU : BTY100

Protein structure
Further Foldings
e
ha v
u
Yo ady
e
alr ied
d
stu tions s
c
n
fun rotei
of p nit-3
in U

LPU : BTY100

Next Class: Manipulating Genes

LPU : BTY100

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