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INFANTS &
CHILDREN
FUNDAMENTAL
DIFFERENCES
Anatomical differences
Respiratory system
Cardiovascular system
Blood
Renal function & fluid balance
Maintenance of body temperature
Psychological differences
Respiratory System
Respiratory rate
Lung capacities
Control of respiration
Causes of bradycardia
Causes of reflex bradycardia &
hypotension during anesthesia:
Laryngoscopy
Tracheal intubation
Tracheal suctioning
Traction on eye muscles & viscera
Variety of anesthetic drugs:
suxamethonium
(succinylcholin), halothane & neostigmine
Blood volume
Pediatric anesthetic
pharmacology
Pharmacokinetics
Liver
Kidney
Pharmacodynamics
Intravenous
anesthetics
Thiopenthone
Methohexitone
Profopol
Opioids
Methohexitone
Thiopentone
: 5-6 mg/kg
Profopol
Morphine
Standard
children
Supplementing balanced
anesthesia in children:
Loading dose
: 100 ug/kg
Maintenance
: 25
Few
problem dose
with
respiratory
ug/kg
depression
and producing excellent
postoperative analgesia (aged over
6 months)
Tube size
Age (years)
=-------------- + 4.5
4
Average weights of
children
(aged from 1 to 12 year)
[ Age (years) + 3 ] x
5
Weight
(kg)
=--------------------------2