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Embryogenesis
&
Classification
Introduction
First
Ventricular septum
Complex
Ventricular septation
Ventricles
Ventricular septation
growth
Muscular septum
During 5th week(day 30), muscular fold extends from
anterior wall of ventricles to floor
appear at middle of ventricle near apex and grows
towards AV valves with concave ridge
Most of initial growth achieved by growth of two
ventricles on each side of ventricular septum
In addition trabeculations from inlet region coalesce
grows into ventricular cavity at slightly different plane
than primary septum
inlet interventricular septum is at same plane as that of
atrial septum
Primary foramen
Communication
Interventricular Foramen
Bordered by concave upper ridge of muscular
interventricular septum and fused AV canal
endocardial tissue, closes at end of week 7
Achieved by growth of three structures: right and
left bulbar ridges and posterior endocardial
cushion tissue
Closes interventricular foramen and connect
ventricular septum to outflow septum
Connecting right ventricle to pulmonary trunk and
left ventricle to aortic trunk
Outflow Tract
Includes
VSD CLASSIFICATION
Anatomic classification
Physiological classification
Perimembranous
Outlet
Inlet
muscular
Perimembranous
most
common defect
80% of surgical and autopsy series
usually extends into muscular, inlet, or outlet areas
synonyms: infracristal, membranous
Outlet
5%-7%
East)
situated just beneath the pulmonary valve
synonyms: supracristal, conal, infundibular,
subpulmonary,doubly committed subarterial
Inlet
5%-8%
posterior
Muscular
5%-20%
Central: mid-muscular,
Physiological classification
Determines
Depends
on size of defect
Resistance
Small
Restrictive
Nonrestrictive
Association
Part
P-LAX
VS
P-SAX
AP-4C
AP-5C
P-SAX b
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