Take home message

6 5

IVIG

4 80-85% 6 -1
10 215/
5 100 1
1.3-1.5 1
2-3
1-2
( 68 )

Emeline G-M et al, kawasaki disease in adults : report of 10 cases, medicine, volume 89, number 3, May 2010.


5/6 or 4/6 +
5
5

38.5
<1
5
3-4

SJS/TEN

SJS/TEN
EBV
Koplik

Nikolsky SSSS SJS/TEN

SLE

 BCG 1

10-15


70%
1
1 1.5cm

EBV


PR
QT Q ST-T X

CRP

BCG


4 + <3 +-

2/3-3/4
BCG



ASO/ASK

TP/Alb AST/ALT/TBil/GT Na/K/Cl BUN/Cre

pro-BNP
ESR
PT/APTT/D /FDP
/
UpToDate


Patient 2009/1 2013/5 222

PCR or 192 86
%
Exposure PCR
Comparison PCR
Outcome
Type of design
Jessica LT et al, Concurrent Respiratory Viruses and Kawasaki Disease, Pediatrics, September 2015,
PCR
VOLUME
136 / ISSUE 3.

PCR
KD

RSV


93 PCR
99 PCR

PCR

Limitation
retrospective
14% PCR
PCR
Prolonged viral shedding( )
RNA 5-6

Jartti T, Lehtinen P, Vuorinen T, Koskenvuo M, Ruuskanen O. Persistence of

rhinovirus and enterovirus RNA after acute respiratory illness in children. J Med
Virol. 2004;72(4):695699pmid:14981776


7-9
IVIG
25%5% 7 IVIG

IVIG

IVIG RAISE

2 Na133mEq/l
2 AST100U/l
2 4

2 80%
1 CRP10mg/dl
1 Plt30 /l
1 12 months
5 IVIG 76% 80

7 IVIG
5-6
5

<5
5 4-5
1-3/5 BCG

CRP Na Alb

14%

2%
1%
0.5

KD



ASA

ASA

IVIG

MR
6

2

http://www.jrc.or.jp/donation/about/refrain/detail_05/

1-2

ACS

Take home message

6 5

IVIG


Robert S, Kawasaki disease: Epidemiology and etiology, UpToDate, last updated Apr 01, 2016.
Robert S, Kawasaki disease: Clinical features and diagnosis, UpToDate, last updated Feb 22, 2016.
Aaron S, Diagnosis and Management of Kawasaki Disease, Am Fam Physician. 2015 Mar
15;91(6):365-371.
http://eye.sjs-ten.jp/doctor/diagnosis
, ! Dr. DVD, 2004, .

, , ( ), , 2015, .
Jessica LT et al, Concurrent Respiratory Viruses and Kawasaki Disease, Pediatrics, September 2015,
VOLUME 136 / ISSUE 3.
Jartti T, Lehtinen P, Vuorinen T, Koskenvuo M, Ruuskanen O. Persistence of rhinovirus and enterovirus
RNA after acute respiratory illness in children. J Med Virol. 2004;72(4):695699pmid:14981776
, 1 , vol.45 No.11(2013).
Emeline G-M et al, kawasaki disease in adults : report of 10 cases, medicine, volume 89, number 3,
May 2010.
http://www.jrc.or.jp/donation/about/refrain/detail_05/