Professional Documents
Culture Documents
System
Stem cells
Remain Specific,
stem irreversibly
cells differentiate
d cell types
Pluripotential Hematopoietic
Stem Cells
Migrate from the bone marrow to the lymphoid
organ, where they proliferate : lymphocytes
Lymphoid cells
Myeloid cells
Composed of : stroma,
hematopoietic cords &
sinusoidal capilarries.
Release of mature blood
cells releasing factors
, e.q. C3,hormone, some
bacterial toxins.
Function : production
blood cells,destruction of
worn-out RBC & storage of
iron derived from the
breakdown of Hb.
The passage of blood cells across a
sinusoid capillary in red bone marrow
MATURATION OF
ERYTHROCYTES
Summary of erythrocyte
maturation
Hemoglobine
concentration
Nuclear volume
gradually
Chromatin
condensation
Extrussion of
pyknotic nucleus
Differentiation of
Erythrocytes
Large cell, lacy chromatin, visible
Proerythroblast nucleoli, basophilic cytoplasm
Myeloblast
Lymphocytes
progenitor
migrate cells in the
bone marrow
up to 18 m, basophilic
Promonocyt cytoplasm, large & slightly
indented nucleus, nucleoli are
e evident
differentiatio
n
Monocyt Macrophage
e
bloodstream --- connective s
tissue
ORIGIN OF PLATELETS
Origin of Platelets
Differentiation
Fragmentation of the
cytoplasm of mature
megakaryocyte
Megakaryocyte
A megakaryocyte in a
section of red bone
marrow.
One nucleus
Granular cytoplasm