Uji Antiinflamasi Daun Jambu Mete (Anacardium occidentale L.

)
Yang Ditimbulkan Pada Telapak Kaki Tikus Putih Jantan

Antiinflammatory Activity of The Cashew Leaves On

Hind Paw of The Male White Rats

Presented by :

1. Graha Ayu Praptiwi

2. Junita Bri Hastuti
3. Ruri Oktavianti
 P Background

1
Inflammation is a natural respon for
tissue damage.

NSAID have been used as anti-

inflammatory therapy but have side
effect like gastrointestinal distrubances
so natural anti-inflammatory is needed.
 Cashew leaves
(Anacardium occidentale
L.) has nature
substances which have
anti-inflammatory
characteristic like tanin,
flavonoid, anakardiol acid
, elagic acid, fenol,
kardol, methyl kardol,
and salisilic acid.

Powder microscopy of A.occidentale Linn

 Purpose & Methods of
P Research

2 This research was a

laboratory design using
experimental method.

Thirty male white rats (2-

3 month) of 100-200 gr
were used in this study
and divided into 6 groups
(5 rats each).
 Male White Rats

Male white rats were fasted for 18

hours and still be drinking

Group III Group IV Group VI

Group II Group V
Group I (EAE I (EAE II (EAE II +
(Na (EAE III
450 900 Na
diclofena 1,8 g/kg
(aq.dest) mg/kg mg/kg diclofena
c) BW)
BW) BW) c)

Measuring first volume of the hind

paw rats
The induction of inflammation was done by
injecting 0,5% carrageenan into the rats paw
Measuring hind paw volume every 30
minutes until 300 minutes
The data will be analyzed with statistically by
ANOVA test and DAI test
Conclusion
 RESULT OF
THE
RESEARCH

The doses of ethyl acetate extract of cashew leaves

have an antiinflammatory effect on hind paw the male
white rats.

The combination doses (group VI) have the

antiinflammatory effects are smaller when compard to the
ethyl acetate extract of cashew leaves with doses 450
mg/kgBW and 900 mg/kgBW.

The 1st and 2nd result are still lower

than natrium diclofenac as a NSAID.
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