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What is Prenatal Drug Exposure?
In 1999, the number of Americans who had tried MA in their lifetime was 9.4
million (Substance Abuse and Mental Health Services Administration, 2002),
double from what it was in 1994 (Office Applied Studies, 1995). By 2004, the
number had reached nearly 12 million (Office of Applied Studies, 2005) (Smith et
al., 2011)
Between 2000 and 2009, the incidence of newborns who exhibited signs of
withdrawal and required treatment for NAS (neonatal abstinence syndrome)
increased from 1.20 to 3.39 per 1000 hospital births per year (Patrick et al., 2009)
Article #1-
Psychomotor developmental effects of prenatal exposure to psychotropic drugs: a study in EFEMERIS database
Methods: Physical and neurological exam during 12, 18, 24, and 36
month visits, BSID (Mental and Psychomotor developmental indices),
behavior checklist questionnaire (147: 89)
Hurault-Delarue, C., Damase-Michel, C., Finotto, L., Guitard, C., Vayssire, C., Montastruc, J., Montastruc, F., & Lacroix, I. (2016). Psychomotor
developmental effects of prenatal exposure to psychotropic drugs: a study in EFEMERIS database. Fundamental & Clinical Pharmacology, 30, 476-482. Doi:
10.1111/fcp.12209
Lewis, M.W., Misra, S., Johnson, H.L., & Rosen, T.S. (2004). Neurological and developmental outcomes of prenatally cocaine-exposed offspring from 12 to 36
months. The American Journal of Drug and Alcohol Abuse, 30(2), 299-320. Doi: 10.1081/ADA-120037380
Patrick S.W., Schumacher R.E., Benneyworth B.D., Krans E.E., McAllister J.M., Davis M.M. Neonatal abstinence syndrome and associated health care
expenditures: United States, 2000-2009. JAMA. 2012;307:1934-1940.
Smith, L.M., LaGasse, L.L., Derauf, C., Newman, E., Shah, R., Haning, W.,, & Lester, B.M. (2011). Motor and cognitive outcomes through three years of age
in children exposed to prenatal methamphetamine. Neurotoxicology and Teratology, 33, 176- 184. Doi: 10.1016/j.ntt.2010.10.004