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Platelet count Normal range
PBS Normocytic, normochromic, Few
spherocytes, increase in
neutrophilic bands, few early WBCs,
3 nucleated RBCs
Urinalysis 3+ blood
Urine and sputum cultures negative
chemistry profile elevated levels of total bilirubin,
alkaline phosphatase, lactate
dehydrogenase, and aspartate
aminotransferase
direct antiglobulin test (DAT) positive
indirect antiglobulin test negative
eluate Negative
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Y
YY
A
ãhat additional laboratory tests
would be of value in establishing
the diagnosis, and what
abnormalities in these tests would
be expected in confirming your
impression?
A
ãhat additional laboratory tests would be of value in establishing the
diagnosis, and what abnormalities in these tests would be expected in
confirming your impression?
´ An increased
reticulocyte count
Y
Y ´ An increased
Osmotic fragility test
!
´ Presence of
urobilinogen because of destruction of
ertythrocytes
A
ãhat additional laboratory tests would be of value in establishing the
diagnosis, and what abnormalities in these tests would be expected in
confirming your impression?
v
Y v
Test ´ An
increased LDH level
YY Y ´ An
increased autohemolysis test and
corrected by the addition of glucose.
A
ãhat is the cause of this type
of anemia?
A
ãhat is the cause of this type of anemia?
A S
6 6 66
6
þ
i Mild, chronic hemolytic anemia associated with
variable vaso-occlusive complications.
i Splenomegaly