Professional Documents
Culture Documents
Dr. MEENU
Assistant Professor,
Shri Guru Ram Rai Institute of Technology & Sciences
2016
Impurities
Definition: A compound is said
to be impure if it is having
foreign matter, i.e. impurities.
Chemical purity implies
freedom from foreign matter. It
means that a pure chemical
refers to that compound which
is having no foreign matter, i.e.
impurities.
Nessler cylinder
Dr. MEENU, Asst. Prof., Dept. of Pharmacy, SGRRITS, Dehradun
Limit test
Type:
1. Comparison method
2. Quantitative determination
3. Test in which there is no visible
reaction
Complete1.5ml
volume
ethanolic
with Dil.water
SO4standard
to 50ml
15ml water
&MIX by rotation
wait
Mixfor
by 1 minute
rotation
1ml 25%BaCl2
Procedure:
2 ml 20% citric acid
2 ml 20% citric acid
2 drops thioglycollic acid
H2O to 40ml 2 drops thioglycollic acid
H2O to 40ml
10ml sample
sample 2 ml
Made slution alkaline
Made slution alkaline
1.2ml thioacetamide
Sample preparation 1.2ml thioacetamide
mix 2.5g aspirin mix
2ml acetate bufferin 30ml 2ml acetate buffer
dissolve
12ml sample 10ml standard Pb
acetone then
2ml sample
complete to 50
ml with H2O
Chemical reaction:
Perchloric acid
It is very corrosive to skin and eyes, It can also ignite or explode upon
contact with organic material such as cloth or wood also Causes
hypothyroidism digestive and respiratory tract burns& it is Corrosive
to metal
glacial acetic acid
This material is strongly corrosive and causes serious
burns. Very harmful if swallowed. Lachrymator