Professional Documents
Culture Documents
Systemic Diseases
1 www.aap.org/oralhealth/pact
Introduction
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Learner Objectives
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Hematologic Disorders
1. Anemia
2. Leukemia
3. Langerhans Cell Histiocytosis
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Anemia
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Leukemia
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Systemic Lupus Erythematosus
Oral ulcers are the most common manifestation and often present
as painless, palatal lesions. Mucosal atrophy can also occur.
Aphthous Ulcer
Oral findings occur in 8% to 10% of
patients with Crohns Disease and may
precede gastrointestinal involvement.
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Xerostomia
1. Diabetes Mellitus
2. HIV
3. Peutz-Jeghers Syndrome
4. Wegeners Granulomatosis
5. Vitamin Deficiencies
6. Bulimia
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Diabetes Mellitus
Patients with diabetes have increased risk for dental caries, oral
candidal infections, and xerostomia.
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HIV
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Wegeners Granulomatosis
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Vitamin C Deficiency
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Vitamin D Deficiency
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Vitamin K Deficiency
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Bulimia
Enamel erosion may expose nerve endings, causing tooth Dentistry, University of Alabama at Birmingham
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Medication Effects on Teeth and Mouth
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Gingival Hyperplasia
Treatment includes meticulous Used with permission from Rocio B. Quinonez, DMD, MS, MPH; Associate
Professor Department of Pediatric Dentistry, School of Dentistry UNC
Candidal plaques
Increased risk in patients with diabetes,
immunosuppression, and xerostomia.
28 Photos used with permission from Dr. Brad W. Neville, DDS, Distinguished University
Professor College of Dental Medicine, MUSC
Staining
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Gastroesophageal Reflux Disease (GERD)
Enamel appears shiny and worn, then may appear yellow as the
underlying dentin becomes exposed.
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Attention Deficit Hyperactivity Disorder
(ADHD)
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Coagulopathies
Avoidance of dental disease can help prevent the need for more
significant interventions, such as a need for factor replacement
for a root canal or extraction.
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See speakers notes for additional info
Coagulopathies
A. Palatal petechiae
B. Enamel erosion of the maxillary incisors
C. Tonsillar enlargement
D. Parotid gland enlargement
E. Scarring of the dorsal aspect of the knuckles
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Answer
A. Palatal petechiae
B. Enamel erosion of the maxillary incisors
C. Tonsillar enlargement
D. Parotid gland enlargement
E. Scarring of the dorsal aspect of the knuckles
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Question #2
A. Hyperdontia
B. Difficult tooth extraction
C. Mucositis
D. Hyperdensity of the mandible
E. Premature tooth exfoliation
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Answer
A. Hyperdontia
B. Difficult tooth extraction
C. Mucositis
D. Hyperdensity of the mandible
E. Premature tooth exfoliation
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Question #3
A. Amoxicillin
B. Penicillin
C. Azithromycin
D. Cephalexin
E. Clindamycin
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Answer
A. Amoxicillin
B. Penicillin
C. Azithromycin
D. Cephalexin
E. Clindamycin
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Question #4
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Answer
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Question #5
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Answer
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References
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References
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www.aap.org/oralhealth/pact
References, continued
15. Red Book: Report of the Committee on Infectious Disease. American Academy of
Pediatrics. 2009; Pickering LK (editor): 826-827.
16. Roberts MW, Tylenda CA. Dental aspects of anorexia and bulimic nervosa.
Pediatrician. 1989; 16(3): 178-184.
17. Schiodt M. Oral Manifestations of Lupus Erythematosus. INT J ORAL SURG.
1984;13(2):101147.
18. Stiller M, Golder W, Doring E. Biedermann T. Primary and secondary Sjgren's
syndrome in children--a comparative study. Clin Oral Investig. 2000 Sep;4(3):176-82.
19. Trost LB, McDonnell JK. Important cutaneous manifestations of inflammatory
bowel disease: review. Postgrad Med J. 2005; 81:580-585.
20. Wilson W, Taubert KA, Gewitz M et al. Prevention of Infective Endocardititis.
Guidelines from the American Heart Association: A Guideline from the American
Association of Rheumatic Fever, Endocardititis, and Kawasaki Disease Committee,
Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology,
Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and
Outcomes Research. Circulation. 2007; 116:1736-1754.
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