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BENEFICIAL TREATMENTS OF

CAT’S WHISKERS
(ORTHOSIPHON STAMINEUS)

SHUKRI BIN JAFFAR


MEB 040045

ENGLISH FOR BIOMEDICAL


SCIENCE
MS. JOTHIMALAR
OUTLINE
• Introduction
• Objectives
• Methodology
• Discussion
• Conclusion
• Recommendations
• References
• Originates from
South East Asia and
subtropical Australia
• Flowers were come
by two colors which
was the purple and
white color
• Traditional remedy
to many type
diseases :
o Kidney problems
o Liver
o Gallbladder
o Urinary tract
•Bioactive compound
was the main
components for
research purpose.
o 5-hydroxy-6, 7, 3,
4-
tetramethoxyflavon
e
o 4, 5, 6, 7-
tetramethoxyflavon
e
• Studies of Mariam A.
et al of extract cat’s
whiskers leaf was
useful where their
study on diabetic have
shown significant in
• Amzad M. study was
examined the
chemical composition
and anti-fungal
properties of oils and
crude extracts of cat’s
whiskers.
• Significant findings
of anti-fungal
properties :
o Botrytis cinerea
o Rhizoctonia
solani
o Fusarium solani
• Khamsiah and
Akawuah study has
proved to be
functional as
antioxidant at
formed of phenolic
group
• To prevent the
diseases:
o Coronary heart
diseases
o Cancers
o Other aging
• The aims of the study are
o To determine the roles
of bio-active compound in
Orthosiphon stamineus
o To determine the types
of method used for
detecting the components
in Orthosiphon stamineus
Effects of Orthosiphon stamineus aqueous extract on
plasma glucose concentration and lipid profile in normal
and streptozotocin-induced diabetic rats
INDUCED
NORMAL
DIABETIC
RATS
RATS
• After 14 days, the
rats’ blood samples
were collected to
determine :
• Blood sugar
• Blood urea
nitrogen (BUN)
• Alanine
aminotransferse
(ALT)
• Asparate
aminotransferase
(AST)
• Cholesterol
• Triglycerides
Chemical composition and anti-fungal properties of the
essential oils and crude extracts of Orthosiphon
stamineus Benth
Anti-fungal activity &
Minimum inhibitory
concentration (MIC)

• R.solani
• B. cinerea
•F. solani
• Colletotricu
capsici
• P. capsici
Sinensetin, eupatorin, 3’-hydroxy-5, 6, 7,
4’-tetramethoxyflavone and rosmarinic acid
contents and antioxidative effect of Orthosiphon
stamineus from Malaysia
•Study on Orthosiphon
stamineus aqueous
extraction were showed
significant reducing the
plasma glucose
concentration on both
normal and diabetic rats.
• After 14 days, the
tested rats were shown
significant in decreasing
the triglyceride and in a
similar way to increase
the plasma HDL-
cholesterol
•Proves that the
leaves of
Orthosiphon
stamineus have
properties of anti-
fungal and
bacteriostatic .
• Composition in
Orthosiphon
stamineus essential
oils had shown
significant study
•Methanol
extracts of
Orthosiphon
stamineus were
showed activity
of antioxidant.
• Antioxidant
activity was
correlation with
the total
• Orthosiphon stamineus had showed
that, there have many potential roles
especially in treatment
• Reduced the plasma glucose
concentration and triglyceride
• Act as natural fungicides to against the
phytopathogens
•Nine components inside essential oils of
Orthosiphon stamineus are the main
compound to be anti-fungal properties.
• Orthosiphon stamineus to be have
antioxidant properties
• To determine the components of
Orthosiphon stamineus by using
the molecular technique.
• Function orthosiphon stamineus
components.
• Knowing the subspecies of
Orthosiphon stamineus.
Arebi, T, Z.Ismail and N. Ismail, Effect of flavonoids from Orthosiphon
stamineus and Malpighis coccigera on the in vitro growth of calcium oxalate
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the Use of the Traditional Medicine and Other Nature Products in health
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Sinensetin, eupatorin, 30-hydroxy-5, 6, 7, 40-tetramethoxyflavone and
rosmarinic acid contents and antioxidative effect of Orthosiphon stamineus
from Malaysia. Food Chemistry 87 (2004) 559–566.

Hsu, F.L., Chen, Y.C., Cheng, J.T,. Caffeic acid as active principle from the
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Lee, W.L., Micropropation and cell culture of misai kucing (Orthosiphon


stamanues Benth) and detection of rosmarinic acid in the in vitro cultures.
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Olah, N.K., Radu, L., Mogosan, C., Hanganu, D., Gocan, S..
Phytochemical and pharmacological studies on Orthosiphon stamineus
Benth. (Lamiaceae) hydroalcoholic extract. J. Pharma. Biomed. Anal.
2003. 33, 117–123.

Sriplang. K, et al Effects of Orthosiphon stamineus aqueous extract on


plasma glucose concentration and lipid profile in normal and
streptozotocin-induced diabetic rats. Journal of Ethnopharmacology 2007,
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