Professional Documents
Culture Documents
Ummi Utami
J5100170066
Pembimbing :
Dr. Heru Iskandar, Sp. B
Date of 2017
Published
Revista do Colgio Brasileiro de
Published by Cirurgies
ABSTRACT
Objective
To study the epidemiological profile of patients with colorectal cancer operated
on an emergency basis at the Bonsucesso Federal Hospital.
Methods
This is a retrospective study of patients operated between January 1999 and
December 2012. We analyzed the following variables: age, gender, clinical data,
TMN staging, tumor location, survival and types of surgery.
Results
130 patients . The most frequent clinical picture was intestinal obstruction, in
78% of cases. The majority (39%) of the patients had advanced TNM staging.
There were 39 deaths (30%). The most common tumor site was the sigmoid
colon (51%). Adjuvant treatment being performed in 40% of the patients.
Distant metastases were found in 42% of the patients and 10% had
documented disease recurrence. Disease-free survival at two and five years
was 69% and 41%.
Conclusion
there was a high mortality rate and a low survival rate in colorectal cancer
patients operated on urgently.
INTRODUCTION
3rd most common type of cancer among men and 2nd among women
Good prognosis when diagnosed in the early stages.
Most common clinical presentation: obstruction, followed by colon
perforation
Design
observational, retrospective,
descriptive study
Place
Surgery Clinic of the
Bonsucesso Federal Hospital
Periode
January 1999 to December
2012
METHODS
Main
Outcomes death and disease-free survival at two and five years.
Software
data collection MS Excel spreadsheet
analyzed with the Bioestat software.
Ethical Clearence
By: Research Committee of the Bonsucesso Federal Hospital
(opinion number 1,183,590).
RESULT
Sample Description
78
72
41
25
15 11
1 2
RESULT
TNM Staging
42
22
13
11
6
3 3
rectum
6%
cecum
8%
transverse colon
9%
ascending colon
16%
RESULT
Type of Procedure
3%
3%
4%
8% Retrosigmoidectomy
39% right hemicolectomy
left hemicolectomy
14% derivative colostomy
total colectomy
transversectomy
derivative ileostomy
29%
RESULT
anastomosis
with stoma
protection
7% none
7%
derivative terminal
stoma stoma
10% 34%
mucosal
fistula
16% simple
primary
anastomosis
26%
Type of intestinal reconstruction
RESULT
Intention of treatment
undetermine
21%
curative
45%
palliative
34%
RESULT
Adjuvant Treatment
no data
35% yes
40%
no
25%
RESULT
Liver 20%
Peritoneum 11%
Uterus 4%
Distant Metastasis 42%
Abdominal wall 2%
Lung 1%
Other site 4%
RESULT
Recurrence 10%
No data 29%
RESULT
Mortality 26 death directly related to CRC
20%
Disease-free survival
Two years 69%