Professional Documents
Culture Documents
Hepatitis A &
VZV Rotavirus HPV Hepatitis B
Individuals
LimitedThe with HIV
dataadministration
on safety
HAV are more
of varicella
vaccine is also Guidelines
A recent recommend
study reporting thatan
Guidelines
andlikely than
efficacy
(VZV) uninfected
in HIV
vaccine has people
been
frequently recently allThis
recommend
combination
increased
girls fromrisk hasadmission
12 of
years of age,
infected populations been demonstrated
torecommended
develop conditionsadministered
Rotavirus in
(RTV)
in HIV infected irrespective
onlywith varicella
of CD4
disease
safe and immunogenic
cellin HIV-
associated withcombination
HPV vaccine with
was not administering
count,
infected
should
children
be vaccinated
compared
RTV vaccine is only
Rotavirus patients withHBV
may CD4+ T
recommended
vaccine
cell after
to infants two doses
recommended in
not be perceived
percentage P15% and
by a
the CD4+
majority T with
with
without HPV
their
vaccine
uninfected peers
byPrecancerous
specialists as a conditions of HAV vaccine was
the first 32 weeks
cell count P200of centres
cells/ll evidences of of life
cervix and anus
high risk infection widely recommendedunderutilisation
immunosuppres
of this
in HIV
sionvaccine in at risk populations
cervical and anal cancer
infected children
Long-term vaccine induced immunity is not
ensured in late treated HIV-infected children,
although they are able to mount an initial
response to routine immunisations and can
have good immune reconstitution
Starting ART within the first Older HIV infected children who
year of life helps preserve have not benefited from early ART
number and function of are therefore at particular risk from
antigen-specific memory B- incomplete protection against
cell vaccine-preventable infection
Children diagnosed
and ART treated by 3
months of age (26%)
Fig. 4. Issues highlighted by results from the survey and some potential
solutions and research directions.
CRITICAL APPRAISAL
USING STANDARD CRITICAL APPRAISAL FOR SECONDARY STUDY
WAS THERE A CLEAR STATEMENT OF THE AIMS OF
THE RESEARCH?
The results were based from the findings on the questionnaire and
presented as numbers and percentages in table and diagrams. The
findings were explicit and related back to the original question.
The researchers also present data that contradicts their argument, for
example in the last question (Would an evidence-based protocol for
checking vaccine serology help your practice?), the researcher
displayed all the answers (Yes, No, Other) not just the answer that
aligned with the research goal (Yes). It would be better if the
researchers elaborate the answer written in the Other column. The
researcher did not discuss the credibility of the study.
HOW VALUABLE IS THE RESEARCH?