Patofisiologi rhinosinusitis akut

Ostium is closed
Nasal congestion or
Mucosal anatomic
thickening creates obstruction blocks
further blockage air flow and
drainage

Bacterial
Mucus secretions
infection
stagnate
develops in the
sinus cavity

Retained mucus
secretions cause
Mucus
tissue
thickens
inflammation

Lack of drainage and

thick mucus create Cilia and
culture medium for epithelium are
bacterial growth in damaged
closed cavity
Murtaza Mustafa, P. Patawari, HM. Iftikhar, SC.Shimmi, SS. Hussain, MM. Sien. 2015. “Acute and Chronic Rhinosinusitis ,
Pathophysiology, and Treatment”. International Journal of Pharmaceutical Science Invention ISSN (Online)
www.ijpsi.org || Volume 4 Issue 2 || February 2015 || PP.30-36
 ETIOLOGI RHINOSINUSITIS AKUT
Virus : rhinovirus, adenovirus, influenza virus, and
parainfluenza virus

Bakteri : Streptococcus pneumoniae, Haemophilus

influenzae, Staphylococcus aureus, streptococcal species
and Moraxella catarrhalis

Fungi : aspergillus, zygomycoses, phaeohyphomycis,

Pseudallescheria, Hyalohyphomycis
Jack M.GwaltneyJr.MD, W.MichaelScheldMD, Merle A.SandeMD, AustinSydnorMD. The microbial etiology and antimicrobial therapy of adults
with acute community-acquired sinusitis: A fifteen-year experience at the University of Virginia and review of other selected studies. Journal
of Allergy and Clinical Immunology Volume 90, Issue 3, Part 2. [Online]. www.sciencedirect.com.