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IDIOPATHIC SPECIFIC UVEITIS SYNDROMES

1. Fuchs uveitis syndrome

2. Intermediate uveitis

3. Juvenile chronic iridocyclitis


4. Acute anterior uveitis in young adults

5. Sympathetic ophthalmitis
Signs of Fuchs uveitis syndrome
• Unilateral, chronic anterior uveitis
• Resistant to therapy

• KP - small and scattered • No posterior synechiae


throughout endothelium
• Diffuse iris stromal atrophy
• Feathery fibrin filaments • Occasionally iris nodules

• Iris retroillumination • Heterochromia iridis -


affected eye is usually
hypochromic
Complications of Fuchs uveitis syndrome

Cataract Angle new vessels Glaucoma

Very common and May bleed during Uncommon but control


frequently surgery may be difficult
presenting feature
Intermediate uveitis
• Typically affects children and young adults
• Insidious and chronic
• Frequently bilateral but asymmetrical
• Usually presents with floaters

Vitritis Vitreous snowballs

Mild peripheral Snowbanking in pars


periphlebitis planitis
Intermediate uveitis
Cystoid macular oedema

Treatment

Posterior sub-Tenon steroids if poor VA


Juvenile chronic iridocyclitis
• Majority are girls
• Initially no systemic disease
• Minority subsequently develop arthritis
Progression of complications

Posterior synechiae Band keratopathy Cataract


Acute anterior uveitis in young adults
• Majority are men
• 45% are positive for HLA-B27
• Initially no systemic disease
• Minority subsequently develop ankylosing spondylitis

Fibrinous exudate Residual pigment on lens


Sympathetic ophthalmitis

Typically follows penetrating Bilateral granulomatous panuveitis


trauma

Granulomatous anterior uveitis Multifocal choroiditis