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Heri Sutrisno
SMF Penyakit Dalam
RSU WZ Johannes Kupang
Introduction:
Myeloproliferative disorders :
1 Polycythemia Vera ( PV )
4 Myelofibrosis ( MF )
CML PV TE MF
AML
Blood smear :
leuco-erithroblastic
( immature leucocyte & erythrocyte ),
poikilositosis: tear-drops cells
extramedullary hematopoesis
in the spleen, liver, limph-node
5 Cachexia
1. Mostly anemia
2. Leucocyte could be < , normal, atau >
(sometimes 50.000 / mm3)
3. Thrombocyte count is vary
Abnormal thrombocyte (giant)
4. Blood smear: poikilositosis,tear-drop cell
(abnormal erythrocyte)
MF
Leuco-erythroblastic :
Found in severe infection, Bone Marrow Fibrosis :
severe inflammation, bone Found in metastatic
marrow infiltration (no tear- carcinoma, Hodgkin,
drops cells & giant Hairy cell leukemia
thrombocyte)