Professional Documents
Culture Documents
As the blood in the glomerulus is at higher pressure than in the Bowman’s capsule, fluid from
the blood is pushed into the Bowman’s capsule
The barrier between the blood in the capillaries, and the lumen of the Bowman’s capsule
consists of:
• Endothelium- having narrow gaps between its cells that plasma can pass through
• Basement Membrane- made of a fine mesh of collagen fibres and glycoproteins
which act as a filter to stop molecules with a relative molecular mass of 69000 getting
through (most proteins and all blood cells)
• Podocytes- epithelial cells of the Bowman’s capsule containing finger like projections
called major processes. These ensure that there are gaps between the cells allowing
fluid to pass into the lumen of the Bowman’s capsule
What is filtered out of the blood?
• Water
• Amino acids
• Glucose
• Urea
• Inorganic ions (sodium, chloride, potassium)
What is left in the capillary?
• Blood cells
• Proteins
This is due to :
This is due to :