PEMERIKSAAN

PATOLOGI ANATOMI DAN KLINIS

Kelompok 2

1. Santi Gita Sari Lombu

2. Mary Lowrenza
3. Sri Lestari Siregar
4. M.Rival Syah
5. Sabran Hadi Pagan
 A. Anatomical pathology
Anatomical pathology is the study of the
morphology of cells, organs, and tissues in the
state of illness. Anatomical pathology is a
surgical pathology, exfoliative cytology,
autopsy pathology.
 How to check anatomical
pathology

1.Perpatologi Special examination (cut frozen)

The goal is a quick-method of hysteresis at the time the patient is still at
surgery because the results of the examination are needed to determine
further surgery.
Inspection material is fresh tissue.

2. Clinical autopsy examination

post-mortem examination at the request of a specialist (child specialist,
internal medicine specialist, etc.), on the corpse who died in hospital care to
determine the cause of death.
LANJUTAN

3. Immunopathology Examination with Immunoflupresence

The goal is to recognize antigens, antibodies, and immune complexes using
Fluochrom seen under a fluorescence microscope, ie a microscope using a filter to
emit UV light.
Inspection materials:
- Fresh biopsy tissue in chill at -80 degrees Celsius by using liquid nitrogen or at -
30 degrees Celsius temperature using dry ice.
- Paraffim block network (the result is not good).

4. Immunohistochemical Examination with Immunoenzyme Technique

The goal is to recognize the type of antigen or material contained within the cell or
tissue.
The trick is to use antibodies (against antigens) or certain substances labeled with
enzymes such as perosidakse or alkaline phosphatase or visualization.
LANUTAN

The benefits of the examination are as follows:

1. To sharpen the diagnosis of pathology by other means:
a. Ensuring histogenetik tumor
b. Ensure tumor subclassification
c. Determining neoplastic or non-neoplastic lesions
d. Detects tumor markers
e. Detects microbial markers
f. Detects oncogenic expression
2. Help predict the biological and protoxic behavior of a tumor
3. Determining treatment
4. Know the type of microorganism or type of infection
The nature of the examination is an advanced stage of routine histopathological
or cytopathological examination that encounters diagnostic difficulties.
The inspection material is fresh tissue cooled at low temperature cytological
preparations or paraffim block tissue.
B. CLINIC PATHOLOGY
Clinical pathology is the application of various other laboratory techniques
to study the disease. Examples of clinical pathology are clinical chemistry,
microbiology, hematolgi, immunology, and immunohepatology.

C. TYPE OF DISEASES
1. Atherosclerosis
Atherosclerosis is a multifactorial disease affecting the intima of the
elastic artery. The disease is characterized by the deposition of
intramular fat, the proliferation of vascular smooth muscle cells and
fibroblasts, as well as the buildup of macrophages.
2. Pneumonia (respiratory disease)
3. Skin cancer (dermatology disease)
The skin consists of three layers of epidermis, dermis and subkutis
jaingan. The purpose of skin examination is to explain a diagnosis
approach to skin diseases. When examining the skin, then some things
to note is first, every lesion should be properly described including the
colors and shapes.