Professional Documents
Culture Documents
• Age-related changes
• acetowhite lesions
• cancer
Natural History of CIN and Cervical Cancer
Normal cervix
HPV infection
About 60% regress
within 2-3 years
HPV - related changes
Invasive cancer
Bishop A, et al. PATH 1995:5
Maturation of immature squamous epithelium
ACETOWHITE (AW)
• area of acetowhite
S
higher nuclear density
Application of Acetic acid
CIN I ,LSIL
Before After
Nabothian cyst
- contact bleeding
- cauliflower growth
- infiltrative lesion
- enlarged and hard on
pelvic examination
INVASIVE CARCINOMA
Flat
ulcer
SUMMARY
- Squamous Epithelium
- Columnar Epithelium
- Squamo-Columnar Junction
- Squamous Metaplasia
- Transformation Zone
- Acetowhite Lesions
- Cancer
Thank You