1) Thyroid incidentalomas refer to small, non-palpable thyroid nodules between 1-15mm discovered incidentally on imaging like ultrasound, CT, or PET scans.
2) The rate of malignancy in thyroid incidentalomas is 15%. Incidental nodules found on PET scans have a 33% malignancy rate, higher than the 11% rate for nodules found on CT scans.
3) The 18% malignancy rate in patients with a pre-existing non-thyroid cancer is not significantly different than the 13% rate in patients without a cancer history. Thyroid incidentalomas should be evaluated for possible biopsy and treatment depending on risk factors and imaging
1) Thyroid incidentalomas refer to small, non-palpable thyroid nodules between 1-15mm discovered incidentally on imaging like ultrasound, CT, or PET scans.
2) The rate of malignancy in thyroid incidentalomas is 15%. Incidental nodules found on PET scans have a 33% malignancy rate, higher than the 11% rate for nodules found on CT scans.
3) The 18% malignancy rate in patients with a pre-existing non-thyroid cancer is not significantly different than the 13% rate in patients without a cancer history. Thyroid incidentalomas should be evaluated for possible biopsy and treatment depending on risk factors and imaging
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1) Thyroid incidentalomas refer to small, non-palpable thyroid nodules between 1-15mm discovered incidentally on imaging like ultrasound, CT, or PET scans.
2) The rate of malignancy in thyroid incidentalomas is 15%. Incidental nodules found on PET scans have a 33% malignancy rate, higher than the 11% rate for nodules found on CT scans.
3) The 18% malignancy rate in patients with a pre-existing non-thyroid cancer is not significantly different than the 13% rate in patients without a cancer history. Thyroid incidentalomas should be evaluated for possible biopsy and treatment depending on risk factors and imaging
Copyright:
Attribution Non-Commercial (BY-NC)
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Download as PPT, PDF, TXT or read online from Scribd
www.palnurse.com Thyroid incident Loma is that nodules which are small and non palpable measuring between 1 mm- 15mm and are incidentally discovered on ultrasound for (neck, parathyroid, carotid) or that discovered by autopsy studies Most incidentalomas from autopsy 30-60% and they are discovered by highly resolution ultrasound which is capable of detecting many small nonpalpable thyroid nodule Most of thyroid nodules are benign, if there is malignancy in the nodules they are called microcarcinoma Most thyroid nodules which is located posteriorly is very difficult to palpate 1/3 of nodules more that 2 cm are detected Imaging studies US: save and sensitive and capable of detecting lesion as small as 1-3 mm Sensitivity 90% specificity 84% Thyroid scintigraphy Tc99m : detect 40% of thyroid incidentaloma on patient who had clinically normal thyroid gland 13% discovered incidental thyroid nodules of carotid neck ultrasound 40% of patient with hyperparathyroidism where discovered to have thyroid incidentalomas How should thyroid incidentaloma managed Patient who have incidentaloma less than 15 mm and in patient with low risk of thyroid cancer >> observation. Patients who have Hx of exposure to radiation during childhood or those who have ultrasonographic feature that suggest malignancy >>> FNA should be done If that lesion was proven to be malignant >> should be treated surgically Benign nodules should be followed up by palpation at 6 months and annually thereafter. Patients who have nodules that smaller than 15 mm that have benign appearance on ultrasonography >> annual neck palpation is sufficient Ultrasound finding in malignant lesions Hypoechogenicity Irregular margin Intranodular calcifications Increase vascularity (Doppler US) Abstract BACKGROUND: The clinical significance of thyroid incidentalomas is controversial. METHODS: The rate of malignancy was determined for patients with an incidentally discovered thyroid nodule, and results were stratified according to imaging modality as well as presence and type of pre- existing malignancy. RESULTS: One hundred fifty patients were identified, of which 88 with a known malignancy were screened for metastases. Twenty-three (15%) patients were diagnosed with thyroid malignancy. Incidental nodules identified on positron emission tomography scan were malignant in 33% of the patients compared with 11% for those identified on computed axial tomography (P .016). The rate of thyroid malignancy in patients with pre- existing nonthyroid malignancy (18%) was not significantly different from patients without a history of malignancy (13%, P .36). COMMENTS: Thyroid incidentalomas are associated with a high rate of malignancy. The rate of malignancy is highest for nodules discovered on positron emission tomography scan and is no different in patients with or without pre-existing malignancy
European Society of Endocrinology Clinical Practice Guidelines On The Management of Adrenal Incidentalomas, in Collaboration With The European Network For The Study of Adrenal Tumors