Professional Documents
Culture Documents
Dr S.Ramesh 31Oct 2010
Scope of this talk
URTI
LRTI
URTI
Common cold
Tonsillitis
Pharyngitis
Sinusitis
Laryngitis
ALTB
Epiglottitis
LRTI
Pneumonia
Bronchiolitis
Bronchitis
WALRI
Symptoms
Cough
Running nose
Stridor
Rhonchi
Creps
Air entry
Incidence of respiratory infections in
the first yr of life
LRTI 33%
Age
Sex
Prematurity
Large family
Causes of recurrent or persistent resp signs
and symptoms
Recurrent µnormal¶ infections V
Asthma V
Idiopathic
Differential diagnosis of
recurrent chest infections
Normal immune and respiratory defences
Normal growth
Entry to school
Asthma
undiagnosed asthma
WALRI
Air entry
K K |K
w Cystic fibrosis
w Tuberculosis
w Ciliary abnormalities
'easles, Pertussis
Tuberculosis
Unusually severe
Recurrent
:ailure to thrive
I disease
Severe infections
Deaths
Consanguinity
Immunodeficiencies
Primary
w About 80
Secondary
w 'alignancy
w Immunosuppression
w HIV
Primary immunodeficiencies
Complement <2%
Prototypes
SCID
K
'easure isohemagglutinins
Not useful
T Cell phenotyping
T Cell function
T Cell Phenotyping
:low cytometry
NBT test
'econium ileus
:ailure to thrive
Rectal prolapse
Nasal polyps
Tests for Cystic fibrosis
1: 16000 to 20000
Autosomal recessive
Undiagnosed
Severe ERD
Atypical asthma
Technically difficult
w Cystic fibrosis
w Tuberculosis
w Ciliary abnormalities
Lung parenchyma
Pulmonary vasculature
Sequestrated lung
Bronchial stenosis
Bronchomalacia
Recurrent pneumonias
Repeated aspiration
!"K#
Investigations
X Ray chest
Cellular specimens
'icrobiological specimens
Study of anatomy
Sweat chlorides
$
'ilk scans
Esophageal ph monitoring
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%
$
:
&
$
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