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Homeostasis
The goal of physiological regulation and the key to survival in a changing environment
Physiology
Is the study of function
Biochemistry
Biology Chemistry
Genetics
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Pronunciation Guides
Checkpoint Questions Tips & Tricks
Colored Tabs
End-of-Book Reference Sections
Clinical Notes
Arrow Icons
Associated structures
Physiology
Is the study of:
Functions of anatomical structures
Individual and cooperative functions
Protein filaments
Complex protein molecule Atoms in combination
Organism level
The heart
Functions
Protects against environmental hazards Helps regulate body temperature Provides sensory information
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Functions
Provides support and protection for other tissues Stores calcium and other minerals Forms blood cells
Functions
Provides movement Provides protection and support for other tissues Generates heat that maintains body temperature
Functions
Directs immediate responses to stimuli Coordinates or moderates activities of other organ systems Provides and interprets sensory information about external conditions
Functions
Directs long-term changes in the activities of other organ systems Adjusts metabolic activity and energy use by the body Controls many structural and functional changes during development
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Functions
Distributes blood cells, water and dissolved materials including nutrients, waste products, oxygen, and carbon dioxide Distributes heat and assists in control of body temperature
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Lymphatic vessels
Lymph nodes Tonsils
Functions
Defends against infection and disease Returns tissue fluids to the bloodstream
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Larynx
Trachea Bronchi
Lungs
Alveoli
Liver
Gallbladder Pancreas
Urethra
Functions
Excretes waste products from the blood Controls water balance by regulating volume of urine produced Stores urine prior to voluntary elimination Regulates blood ion concentrations and pH
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Ductus deferentia
Seminal vesicles Prostate gland
Penis
Scrotum
Sexual intercourse
Major Organs
Ovaries Uterine tubes Uterus Vagina Labia Clitoris Mammary glands
Sexual intercourse
1-6 Homeostasis
Homeostasis
All body systems working together to maintain a
1-6 Homeostasis
Mechanisms of Regulation
Autoregulation (intrinsic)
Automatic response in a cell, tissue, or organ to some environmental change
Extrinsic regulation
Responses controlled by nervous and endocrine
systems
1-6 Homeostasis
Receptor
Receives the stimulus
Control center
Processes the signal and sends instructions
Effector
Carries out instructions
RECEPTOR
Normal condition disturbed Thermometer Information affects
RESPONSE: Room temperature drops Normal condition restored EFFECTOR Air conditioner turns on
20 30 40
22
Normal range
Sends commands to
In response to input from a receptor (a thermometer), a thermostat (the control center) triggers an effector response (either an air conditioner or a heater) that restores normal temperature. In this case, when room temperature rises above the set point, the thermostat turns on the air conditioner, and the temperature returns to normal.
Time With this regulatory system, room temperature fluctuates around the set point.
RECEPTORS Temperature sensors in skin and hypothalamus Information affects CONTROL CENTER
STIMULUS: Body temperature rises HOMEOSTASIS Normal body temperature Thermoregulatory center in brain
RESPONSE: Increased heat loss, body temperature drops EFFECTORS Sweat glands in skin increase secretion Blood vessels in skin dilate Sends commands to
37.2 37 36.7
Normal range
Events in the regulation of body temperature, which are comparable to those shown in Figure 12. A control center in the brain (the hypothalamus) functions as a thermostat with a set point of 37C. If body temperature exceeds 37.2C, heat loss is increased through enhanced blood flow to the skin and increased sweating.
Time The thermoregulatory center keeps body temperature fluctuating within an acceptable range, usually between 36.7 and 37.2C.
stimulus
Body is moved away from homeostasis
Normal range is lost
Chemicals
Chemicals
Blood clot
Damage to cells in the blood vessel wall releases chemicals that begin the process of blood clotting.
The chemicals start chain reactions in which cells, cell fragments, and soluble proteins in the blood begin to form a clot.
As clotting continues, each step releases chemicals that further accelerate the process.
This escalating process is a positive feedback loop that ends with the formation of a blood clot, which patches the vessel wall and stops the bleeding.
Anatomical Landmarks
Anatomical position: hands at sides, palms forward Supine: lying down, face up Prone: lying down, face down
Anatomical Regions
Body regions Abdominopelvic quadrants
Abdominopelvic regions
Anatomical Directions
Reference terms based on subject
Frontal or forehead
Cranial or skull Cephalic or head Facial or face Oral or mouth Mental or chin Axillary or armpit Brachial or arm
Otic or ear
Buccal or cheek Cervical or neck Thoracic or thorax, chest Mammary or breast Abdominal (abdomen) Umbilical or navel Trunk
Anterior view
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Pelvic (pelvis)
Trunk
Manual or hand
Pollex Digits or thumb (phalanges) or fingers (digital or phalangeal) Patellar or kneecap Crural or leg Tarsal or ankle
Digits (phalanges) or toes (digital or phalangeal) Hallux or great toe
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Pedal or foot
Anterior view
Cephalic or head
Cervical or neck
Upper limb
Posterior view
Lumbar or loin
Upper limb
Gluteal or buttock
Lower limb
Posterior view
Abdominopelvic quadrants. The four abdominopelvic quadrants are formed by two perpendicular lines that intersect at the navel. The terms for these quadrants, or their abbreviations, are most often used in clinical discussions.
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Epigastric region
Umbilical region
Hypogastric (pubic) region
Abdominopelvic regions. The nine abdominopelvic regions provide more precise regional descriptions.
Stomach
Spleen
Urinary bladder
Anatomical relationships. The relationship between the abdominopelvic quadrants and regions and the locations of the internal organs are shown here.
Superior
Right
Left
Proximal
Posterior or dorsal
Anterior or ventral
Lateral Caudal
Medial
Proximal Distal
Inferior
Distal
A lateral view.
An anterior view. Arrows indicate important directional terms used in this text; definitions and descriptions are given in Table 12.
MRI
PET CT
Transverse plane
Thoracic cavity
Abdominopelvic cavity
Figure 1-9 Relationships among the Subdivisions of the Ventral Body Cavity
Thoracic Cavity
Surrounded by chest wall and diaphragm
Abdominopelvic Cavity
Peritoneal Cavity
Extends throughout abdominal cavity and into superior portion of pelvic cavity
Mediastinum
Contains the trachea, esophagus, and major vessels
Abdominal Cavity
Contains many digestive glands and organs
Pelvic Cavity
Contains urinary bladder, reproductive organs, last portion of digestive tract
Pericardial Cavity
Surrounds heart
Mediastinum
Upper portion filled with blood vessels, trachea, esophagus, and thymus Lower portion contains pericardial cavity The heart is located within the pericardial cavity
POSTERIOR
ANTERIOR
Diaphragm
Parietal pericardium
ANTERIOR
Pericardial cavity
Pleural cavity
Parietal pleura Mediastinum Spinal cord
Right lung
Left lung
POSTERIOR
Diaphragm to top of pelvic bones Contains digestive organs Retroperitoneal space Area posterior to peritoneum and anterior to muscular
body wall
Contains pancreas, kidneys, ureters, and parts of the digestive tract
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