Professional Documents
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A Pathophysiologic Approach
Third Edition
CHAPTER
More specific than therapeutic classification Requires understanding of biochemistry and physiology May be described with varying degrees of complexity
Pharmacology for Nurses: A Pathophysiologic Approach, Third Edition Adams Holland Copyright 2011 by Pearson Education, Inc. All rights reserved.
Examples
Calcium-channel blockers Diuretics Adrenergic antagonists
Generic Name
Assigned by the US Adopted Name Council Less complicated and easier to remember
Trade Names
After 17 years, competing companies may sell a generic equivalent drug, sometimes using a different name, which the FDA must approve
Rights Issues
Pharmaceutical company with exclusive rights to a drug often prices it very high When rights end, competing companies offer the generic form of the drug for less money
psychologically dependent little physical discomfort when drug is withdrawn, but intense compelling desire to continued use
Pharmacology for Nurses: A Pathophysiologic Approach, Third Edition Adams Holland Copyright 2011 by Pearson Education, Inc. All rights reserved.
Controlled Substances
Controlled substances are drugs that:
Are restricted by the Controlled Substances Act of 1970 Are frequently abused Have a high potential for addiction or dependence Have restricted use Are placed into one of five schedules
Controlled Substances
Anyone convicted of unlawful manufacturing, distributing, and dispensing of controlled substances faces severe penalties
Scheduled Drugs
Drugs that have a significant potential for abuse are placed into five categories called schedules
Schedule I drugs have highest abuse potential, Schedule V the lowest
Schedule I Drugs
Restricted to situations of medical necessity, if allowed at all Little or no therapeutic value; mostly used for research
Schedule II Drugs
High abuse potential High potential for physical and psychological dependence Therapeutic use with prescription Some drugs no longer used
Schedule IV Drugs
Lower abuse potential Lower potential for physical and psychological dependence Therapeutic use with prescription
Schedule V Drugs
Lowest abuse potential Lowest physical and psychological dependence Therapeutic use without prescription Examples
OTC cough medicines with codeine
Narcotic drugs must be labeled with the letter N on the outside of the container