Professional Documents
Culture Documents
(MLTHSC1042)
Nilaian Penilaian berterusan Peperiksaan akhir : 2 Jam kredit : 40%(Mid sem & Assigment) : 60%
Oleh:
Tel: 013-3452970 Lecturer Medical Lab Technology Department Science and Technology Islamic College
INTRO.
1. Definition 2. Importanc e 3. Immunity type 4. Immunity characteris tic)
HOW
Antigen Antibody Agglutination Non-specific immunologic reaction First barrier Scnd barrier 5. Specific immunologic reaction Third barrier 6. Cytokines
DISEASE
1. Hipersen sitiviti 2. HLA 3. Immunol ogical disorder
TEST
1. Immun oesei 2. Immun openda flour
REFERENCE BOOKS
1. A SHORT COURCE IMMUNOLOGY FIFTH EDITION Author: Richard coico, Geoffrey sunshine, El Benjamin 2. A SHORT COURCE IMMUNOLOGY SECOND EDITION Author: Eli Benjamin and friends 3. Others
PENGENALAN
Objektif pembelajaran:
1. Memahami definisi immunologi dari segi bahasa dan istilah 2. Mengetahui kepentingan sistem imun 3. Mengetahui jenis-jenis sistem imun dalam manusia beserta ciri2 umumnya
DEFINISI
Immunologi Immun-pertahanan badan logi- Pengetahuan/Ilmu/ Definisi: Bagaimana sistem badan melindungi badan daripada patogen dan bahan-bahan yang merbahaya
Melindungi badan daripada bahan-bahan yang merbahaya (virus, bakteria, fungi, patogen, parasit dll) Memusnahkan sel yang tidak normal dalam badan (sel kanser) Mencegah daripada berlakunya pemusnahan sel sendiri (Autoimmune disease)
Kepentingan pada masa akan datang.. Gabungan bidang immunologi, genetik dan bioteknologi menyumbang kpd pemahaman tentang: Jangkitan Kanser yg melibatka sum-sum tulang dan sel darah Reaksi allergik Penyakit autoimmune Penyakit kekurangan sel2 dlm sistem imun Penyakit berkaitan dengan immunosuppresion
JENIS
1) INNATE IMMUNITY 2) ACQUIRED IMMUNITY
CIRI-CIRI UMUM
NATURAL IMMUNITY (semulajadi)
1. 2. 3. 4.
Tidak spesifik pada antigen tertentu Respon segera dan cepat (minit) Tiada memori Komponen imuniti:
Spesifik terhadap antigen tertentu Respon yang lambat(beberapa hari) Mempunyai memori Komponen immuniti:
Limfosit Antibody
Physical barrier (Perlindungan fizikal) - skin - mucous membrane in respiratory - hairs in the nasal tract - lining cells of the intestinal tract
2) Chemical barrier (perlindungan kimia) - gastric juice - saliva (air liur) - sweat (peluh) - tears - human milk
3) Phagocytosis - phagocyte cells engulf and destroy an invading organism, cellular debris, toxin and foreign body.. *phagocytic cells - Neutrophil and macrophages
4) Action of natural killer cells - non-specific, non-phagocytic cells which can damage virus-infected tissue cells.. 5) Action of bodys natural microbial flora (bacteria normally found in certain part of the body) 6) Influence by genetic factor
Specific immune reaction against a foreign antigen (invading organism, harmful cell or toxic substance) 2 types of reaction
Immune cells (T-Lymphocyte and macrophages) directly attack intracellular pathogens, tumor cells and foreign tissue
Acquired Immunity
Active Passive
Occurs when:
Naturally when the body exposed to infection Artificially when a person is stimulated to produce antibodies (immunized or vaccinated against a particular disease)
Antibody that has been formed in another person/animal are introduced into the body of a non-immune person (antibody transfer) Occurs when:
Naturally (from placenta to baby during pregnancy, breast milk) Artificially (receive antitoxin/gammaglobulin in the treatment)
Kesimpulan
Natural (Non-specific)
Acquired (Specific)
Mechanical barrier Chemical barrier Phagocytosis Killer cells Bodys natural microbial flora Genetic factor
Pasive
Active
Infection Immunization/vaccination
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