Colchicum autumnale Liliaceae Widely distributed in Europe Derived its name from Colchis area on Black sea where it was found Recommended for Gout in Arabian writings.
Colchicum autumnale Liliaceae Widely distributed in Europe Derived its name from Colchis area on Black sea where it was found Recommended for Gout in Arabian writings.
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Colchicum autumnale Liliaceae Widely distributed in Europe Derived its name from Colchis area on Black sea where it was found Recommended for Gout in Arabian writings.
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as PPT, PDF, TXT or read online from Scribd
Obtained from Colchicum autumnale Liliaceae Widely distributed in Europe Derived its name from Colchis area on Black sea where it was found Recommended for Gout in Arabian writings Life cycle Corm consists of enlarged underground stem bearing foliage leaves , sheathing leaves & fibrous roots In later part of summer new corm is developing in the axils of a scale leaf near the base of old corm In Sept the parent corm bears the remains of recently withered leaves & is larger than daughter corm For medicinal purposes the corm would have been collected shortly after withering of the leaves & before enlargement of its axial bud Life cycle The corms are surrounded by a dark membranous coat Young corm develops fibrous roots at its base In Aug / Sept 2 – 6 flowers emerge from it but its foliage leaves do not appear above ground level until the following spring More than half the length of the flower is below the ground & fruit lies protected throughout the winter by surrounding corm & earth Fruit is 3 lobed , 3 celled , septicidal capsule & is carried above ground in the spring by expanding leaves During these changes the daughter corm grows at the expense of parent which gradually perishes .Before that it may produce in its second spring one or more small corms Fruit development Lilac / purple flowers appear from Aug to Oct & are similar to crocus , hence called autumn crocus The slowly developing fruit remains below ground during autumn & winter A rosette of linear lanceolate leaves(3 or 4)develops in spring & in its center the capsular fruit carried above ground by the lengthening of its stalk Fruit dehisces septicidally into 3 valves & liberates numerous seeds which ripen in june to July Collection Capsules collected about the end of May – June before they split open Dried by enclosing in muslin cloth & hanging them in dry place until they dehisce & liberate seeds Separated by sifting As they ripen they darken in colour & become covered with a saccharine exudation (Glc) Description Shape ovoid / globular / subspherical Testa extremely hard dull , dark reddish brown minutely pitted & rough Odourless Unpleasant bitter taste From the hilum there extends for about ¼ of the circumference a well marked strophiole & is present over raphe Microscopy Testa thick walled , reddish brown parenchyma Endosperm pitted walls , yellowish & oily (fixed oil & aleurone grains ) Strophiole contain starch Embryo Constituents
Allparts of plant contain alkaloid Colchicine
Colchico resin Fixed oil Glucose Uses Chieflyused to relieve the pain & inflammation Shorten the duration of acute gout Large doses cause death due to respiratory failure Polyploidy inducer Used in leukemia
Tests With 60 – 70 % H 2SO4 / conc HCl yellow colour Alc .solution of colchicine with FeCl3 red colour